Results 31 to 40 of about 1,534 (157)
Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction [PDF]
Proceedings of the National Academy of Sciences, 2010 In contrast to the current state of knowledge in the field of eukaryotic chromosome segregation, relatively little is known about the mechanisms coordinating the appropriate segregation of bacterial chromosomes. In Escherichia coli , the MukB/E/F complex and topoisomerase IV (Topo IV) are both crucial players in ...
Yinyin, Li +7 more
openaire +2 more sources
Using Fluorescence Recovery After Photobleaching (FRAP) to study dynamics of the Structural Maintenance of Chromosome (SMC) complex in vivo [PDF]
, 2016 The SMC complex, MukBEF, is important for chromosome organization and segregation in Escherichia coli. Fluorescently tagged MukBEF forms distinct spots (or 'foci') in the cell, where it is thought to carry out most of its chromosome associated activities.
A Badrinarayanan +21 more
core +2 more sources
Dynamic nature of SecA and its associated proteins in Escherichia coli.
Frontiers in Microbiology, 2015 Mechanical properties such as physical constraint and pushing of chromosomes are thought to be important for chromosome segregation in Escherichia coli and it could be mediated by a hypothetical molecular tether.
Shun eAdachi +4 more
doaj +1 more source
Prices and Portfolio Choices in Financial Markets: Theory, Econometrics, Experiments [PDF]
, 2007 Many tests of asset-pricing models address only the pricing predictions, but these pricing predictions rest on portfolio choice predictions that seem obviously wrong.
Bossaerts, Peter +2 more
core +2 more sources
Structural basis for the MukB‐topoisomerase IV interaction and its functional implications in vivo [PDF]
The EMBO Journal, 2013 Chromosome partitioning in Escherichia coli is assisted by two interacting proteins, topoisomerase (topo) IV and MukB. MukB stimulates the relaxation of negative supercoils by topo IV; to understand the mechanism of their action and to define this functional interplay, we determined the crystal structure of a minimal MukB-topo IV complex to 2.3 Å ...
Seychelle M, Vos +3 more
openaire +2 more sources
Tuned SMC Arms Drive Chromosomal Loading of Prokaryotic Condensin. [PDF]
, 2017 SMC proteins support vital cellular processes in all domains of life by organizing chromosomal DNA. They are composed of ATPase "head" and "hinge" dimerization domains and a connecting coiled-coil "arm." Binding to a kleisin subunit creates a closed ...
Basfeld, A. +5 more
core +3 more sources
Frontiers in Microbiology, 2019 The Escherichia coli CrfC protein is an important regulator of nucleoid positioning and equipartition. Previously we revealed that CrfC homo-oligomers bind the clamp, a DNA-binding subunit of the DNA polymerase III holoenzyme, promoting colocalization of
Saki Taniguchi +3 more
doaj +1 more source
Global dissemination of a multidrug resistant Escherichia coli clone. [PDF]
, 2014 Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant (MDR) clone responsible for a high proportion of urinary tract and bloodstream infections. The rapid emergence and successful spread of E.
A. Pascual +38 more
core +3 more sources
Cell Reports, 2015 The type II topoisomerase TopoIV, which has an essential role in Escherichia coli chromosome decatenation, interacts with MukBEF, an SMC (structural maintenance of chromosomes) complex that acts in chromosome segregation.
Pawel Zawadzki +6 more
doaj +1 more source
Specialized interfaces of Smc5/6 control hinge stability and DNA association [PDF]
, 2017 The Structural Maintenance of Chromosomes (SMC) complexes: cohesin, condensin and Smc5/6 are involved in the organization of higher-order chromosome structure—which is essential for accurate chromosome duplication and segregation.
A Chiu +65 more
core +1 more source