Dynamic molecular linkers of the genome: the first decade of SMC proteins [PDF]
, 2005 Structural maintenance of chromosomes (SMC) proteins are chromosomal ATPases, highly conserved from bacteria to humans, that play fundamental roles in many aspects of higher-order chromosome organization and dynamics.
Hirano, T., Losada, A.
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Microorganisms, 2019 Prokaryotes have an essential gene—gyrase—that catalyzes negative supercoiling of plasmid and chromosomal DNA. Negative supercoils influence DNA replication, transcription, homologous recombination, site-specific recombination, genetic ...
Nikolay S. Rovinskiy +3 more
doaj +1 more source
An integrative, multi-scale, genome-wide model reveals the phenotypic landscape of Escherichia coli. [PDF]
, 2014 Given the vast behavioral repertoire and biological complexity of even the simplest organisms, accurately predicting phenotypes in novel environments and unveiling their biological organization is a challenging endeavor.
Carrera, Javier +5 more
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ATP-Induced Shrinkage of DNA with MukB Protein and the MukBEF Complex of Escherichia coli [PDF]
Journal of Bacteriology, 2008 ABSTRACT Fluorescence microscopic observation of individual T4 DNA molecules revealed that the MukBEF complex (bacterial condensin) and its subunit, the MukB (a member of the SMC [structural maintenance of chromosomes] superfamily) homodimer, of Escherichia coli markedly shrunk large DNA molecules in the ...
Ning, Chen +7 more
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SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates? [PDF]
, 1999 The assembly of mitotic chromosomes is a fundamental cellular event that ensures the faithful segregation of genetic information during cell division. It involves two processes that are, in principle, mechanistically distinct.
Hirano, T.
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Molecular Microbiology, Volume 122, Issue 1, Page 81-112, July 2024.In this review article, the diverse mechanisms by which bacterial chromatin proteins influence and are influenced by transcription and DNA supercoiling are discussed. Abstract DNA in bacterial chromosomes is organized into higher‐order structures by DNA‐binding proteins called nucleoid‐associated proteins (NAPs) or bacterial chromatin proteins (BCPs ...
Christine M. Hustmyer, Robert Landick
wiley +1 more source
Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry [PDF]
, 2014 The RNase E family is renowned for being central to the processing and decay of all types of RNA in many species of bacteria, as well as providing the first examples of endonucleases that can recognize 50 -monophosphorylated ends thereby increasing
Andrade +67 more
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Cell boundary confinement sets the size and position of the E. coli chromosome [PDF]
, 2019 Although the spatiotemporal structure of the genome is crucial to its biological function, many basic questions remain unanswered on the morphology and segregation of chromosomes.
Chaudhuri, Debasish +11 more
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Identification and characterization of the smbA gene, a suppressor of the mukB null mutant of Escherichia coli [PDF]
Journal of Bacteriology, 1992 The mukB gene encodes a protein involved in chromosome partitioning in Escherichia coli. To study the function of this protein, we isolated from the temperature-sensitive mukB null mutant and characterized 56 suppressor mutants which could grow at 42 degrees C. Ten of the mutants also showed cold-sensitive growth at 22 degrees C.
K, Yamanaka +3 more
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Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli [PDF]
, 2014 Escherichia coli endoribonuclease E has a major influence on gene expression. It is essential for the maturation of ribosomal and transfer RNA as well as the rapid degradation of messenger RNA.
Clarke, JE +3 more
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