A Collaborative Approach to Pediatric Genetic Evaluation in the Era of Genomic Medicine
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT To address the increased demand for genetic services and shortage of medical geneticists (MG), a collaborative pilot program was developed with a two‐part approach to care: (1) Initial genetic counselor (GC) appointment with exome sequencing (ES) and (2) follow‐up MG evaluation.
Sarah Jurgensmeyer Langas +5 more
wiley +1 more source
PREFERENTIAL SEGREGATION OF STRUCTURALLY MODIFIED CHROMOSOMES IN MAIZE [PDF]
, 1959 M H Emmerling
openalex +1 more source
Shennong 1 Chicken 40K Liquid Chip: Advancing Genetic Research in Chinese Indigenous Chickens
Animal Research and One Health, EarlyView.Based on comprehensive genomic data of Chinese indigenous chickens, we developed a specialized genotyping array for this population. Comparative analyses with published mainstream arrays and evaluations, including genetic assessment of diverse chicken types and gene mining analyses, demonstrated its superior applicability to Chinese indigenous chickens.
Chaoqun Gao +14 more
wiley +1 more source
Regulation of chromosome replication and segregation in bacteria [PDF]
, 1966 Karl G. Lark
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Effects of chromosome number reduction on mitotic and meiotic stability in fission yeast
Genome BiologyBackground Genetic information is stored on multiple chromosomes in eukaryotic organisms and is passed on to offspring through cell division. How chromosome number influences cell division and chromosome segregation is not yet understood. Results In this
Yueyue Jiang +10 more
doaj +1 more source
CHROMOSOME SEGREGATION IN TRANSLOCATIONS INVOLVING CHROMOSOME 6 IN MAIZE [PDF]
, 1950 C. R. Burnham
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When the Clock Is Ticking: The Role of Mitotic Duration in Cell Fate Determination
BioEssays, EarlyView.Recently, several studies identified mechanisms by which cells measure mitotic duration and how this influences cell fate, leading to normal cell cycle progression or G1 arrest. In light of drug‐resistant cancer cells that continue proliferating even after mitotic errors, understanding these mechanisms opens the door for new potential therapeutic ...
Cornelia Sala, Elmar Schiebel
wiley +1 more source
UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer
Molecular & Cellular Oncology, 2018 Defects in mitosis can lead to aneuploidy, which is a common feature of human cancers. Spindle Assembly Checkpoint (SAC) controls fidelity of chromosome segregation in mitosis to prevent aneuploidy. The ubiquitin receptor protein Ubiquitin Associated and
Ksenia Krupina +5 more
doaj +1 more source
GENETIC STUDIES ON SELECTIVE SEGREGATION OF CHROMOSOMES IN SCIARA COPROPHILA LINTNER [PDF]
, 1936 Helen Smith-Stocking
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The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability
Cytoskeleton, EarlyView.ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou +6 more
wiley +1 more source