Results 141 to 150 of about 94,426 (241)

Go for Gold: Development of a Scalable Synthesis of [1‐(Ethoxycarbonyl)cyclopropyl] Triphenylphosphonium Tetrafluoroborate, a Key Reagent to Explore Covalent Monopolar Spindle 1 Inhibitors

ChemistryOpen, EarlyView.
[1‐(Ethoxycarbonyl)cyclopropyl] triphenylphosphonium tetrafluoroborate is a limiting key reagent for synthesis of the tricyclic 5,6‐dihydropyrimido[5,4‐e]indolizine and related scaffolds, which are central to First‐in‐Class covalent inhibitors of the protein kinase monopolar spindle 1/threonine tyrosine kinase (TTK).
Leon Rebhan, Rebekka Fürst, Dieter Schollmeyer, Ricardo A. M. Serafim, Matthias Gehringer   +4 more
wiley   +1 more source

Microtubule poleward flux as a target for modifying chromosome segregation errors. [PDF]

Proc Natl Acad Sci U S A
Risteski P, Martinčić J, Jagrić M, Tintor E, Petelinec A, Tolić IM.   +5 more
europepmc   +2 more sources

Mitotic exit in mammalian cells

Molecular Systems Biology, 2009
Orsolya Kapuy, Enuo He, Frank Uhlmann, Béla Novák   +3 more
doaj   +1 more source

Reproductive adverse events in patients with non‐Hodgkin lymphoma treated with chemotherapeutic regimens including cyclophosphamide, doxorubicin, vincristine, prednisone or CHOP with rituximab: A systematic review and meta‐analysis

Pediatric Discovery, EarlyView.
The regimen of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP with rituximab (R‐CHOP) is the first‐line treatment for non‐Hodgkin lymphoma (NHL). Nine articles involving 331 patients were included in the meta‐analysis, the pooled proportion of reproductive adverse events was 22.3% (95% CI 11.4%–33.2%; p < 0.001). The findings
Rong Han, Jie Zhao, Chengjun Yu, Ling Wang, Long Chen, Yang Hu, Shengde Wu   +6 more
wiley   +1 more source

Double-checking chromosome segregation. [PDF]

J Cell Biol, 2023
Maiato H, Silva S.
europepmc   +1 more source

Chromatin epigenetics and nuclear lamina keep the nucleus in shape: Examples from natural and accelerated aging

Biology of the Cell, Volume 115, Issue 1, January 2023., 2023
We review here recent studies reporting the importance of both nuclear lamina components and epigenetic modifications of chromatin in nuclear mechanics. Perturbation of chromatin condensation or nuclear lamina has been linked to a plethora of biological conditions whose most studied examples are accelerated Hutchinson‐Gilford Progeria Syndrome (HGPS ...
Pietro Salvatore Carollo, Viviana Barra
wiley   +1 more source

Chromosome segregation errors during early embryonic development. [PDF]

Reprod Med Biol
Kyogoku H.
europepmc   +1 more source

A dynamic population of prophase CENP-C is required for meiotic chromosome segregation. [PDF]

PLoS Genet, 2023
Fellmeth JE, Jang JK, Persaud M, Sturm H, Changela N, Parikh A, McKim KS.   +6 more
europepmc   +1 more source

A comprehensive review of the genetic control of cooking time in dry beans (Phaseolus vulgaris L.)

PLANTS, PEOPLE, PLANET, EarlyView.
Reducing cooking time could increase dry beans (Phaseolus vulgaris) consumption. Cooking is an essential processing step needed to unlock the nutrients in dry beans and to make them palatable and safe for consumption. Long cooking times have consequences for dry bean use, especially where cooking fuel cost is high and when people prefer foods that are ...
Hannah R. Jeffery, Marcelo Efrén Murillo‐Quesada, Luis Barboza‐Barquero, Karen Cichy   +3 more
wiley   +1 more source

Hepatitis B virus movement through the hepatocyte: An update

Biology of the Cell, Volume 114, Issue 12, Page 325-348, December 2022., 2022
Model of intracellular trafficking routes of progeny hepatitis B virus (HBV) viral and subviral particles through the liver cell involving nucleocytoplasmic shuttling, movement through the ER/Golgi secretory pathway, and budding and release through the multivesicular body (MVB) and/or secretory autophagosomes (sAP) axis.
Reinhild Prange
wiley   +1 more source