Results 161 to 170 of about 923,115 (353)

A mitosis-specific and R loop–driven ATR pathway promotes faithful chromosome segregation

Science, 2018
Lilian Kabeche, Hai Dang Nguyen, R. Buisson, L. Zou   +3 more
semanticscholar   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

CHROMOSOME SEGREGATION INFLUENCED BY TWO ALLELES OF THE MEIOTIC MUTANT c(3)G IN DROSOPHILA MELANOGASTER 1 2 [PDF]

, 1972
Jeffrey C. Hall
openalex   +1 more source

Genetic etiologies with a large NGS panel in a monocentric cohort of 1000 patients with pediatric onset epilepsies

Epilepsia Open, EarlyView.
Abstract Objective Genetic testing is now included in the diagnostic assessment of childhood onset epilepsies. We evaluated the yield of a targeted next generation sequencing (TNGS) panel dedicated to pediatric epilepsies. Methods We tested by TNGS panel 1000 consecutive patients presenting with childhood onset epilepsies and including mainly patients ...
Giulia Barcia, Nicole Chemaly, Stéphanie Gobin‐Limballe, Emma Losito, Mélodie Aubart, Eugénie Sarda, Zahra Assouline, Pauline Plante‐Bordeneuve, Marie Hully, Remi Barrois, Christine Barnerias, Doxa Sareidaki, Delphine Coste Zeitoun, Monika Eisermann, Cécile Fourrage, Sylvain Hanein, Marlène Rio, Nathalie Boddaert, Isabelle Desguerre, Anna Kaminska, Julie Steffann, Rima Nabbout   +21 more
wiley   +1 more source

RECOMBINATION AND CHROMOSOME SEGREGATION DURING THE SINGLE DIVISION MEIOSIS IN SPO12–1 AND SPO13–1 DIPLOIDS [PDF]

, 1980
Sue Klapholz, Rochelle Easton Esposito
openalex   +1 more source

ASPM Induces Radiotherapy Resistance by Disrupting Microtubule Stability Leading to Chromosome Malsegregation in Non‐Small Cell Lung Cancer

Exploration, EarlyView.
Abnormal spindle‐like microcephaly‐associated protein helps radiotherapy resistant cells to evade spindle checkpoint surveillance and complete cell division after irradiation through destruction of microtubule stability, with subsequent increases in chromosome mis‐segregation and deteriorating chromosomal stability during mitosis to promote ...
Tao Zhong, Ning Liu, Juan Wang, Songbo Xie, Lisheng Liu, Minglei Wang, Fei Wu, Xiaozheng Chen, Changyan Xiao, Xiaoxiao Gongye, Meng Wu, Liewei Wen, Jinming Yu, Dawei Chen   +13 more
wiley   +1 more source

A dependent pathway of gene functions leading to chromosome segregation in Saccharomyces cerevisiae. [PDF]

, 1982
John S. Wood, Leland H. Hartwell
openalex   +1 more source

Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors

Human Reproduction Update, 2018
Jessica Greaney, Zhe Wei, H. Homer
semanticscholar   +1 more source

Chromosome Segregation

Definitions, 2020

semanticscholar   +1 more source

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

International Journal of Cancer, EarlyView.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert, Claire Vargas, Sina Jasmin Wille, Karsten Rippe   +3 more
wiley   +1 more source