Results 161 to 170 of about 1,033,685 (362)

Effects of chromosome number reduction on mitotic and meiotic stability in fission yeast

Genome Biology
Background Genetic information is stored on multiple chromosomes in eukaryotic organisms and is passed on to offspring through cell division. How chromosome number influences cell division and chromosome segregation is not yet understood. Results In this
Yueyue Jiang, Yanze Jian, Lingyun Nie, Xin Gu, Ziyi Lu, Yongkang Chu, Xing Liu, Xuebiao Yao, Jin-Qiu Zhou, Shengnan Zheng, Chuanhai Fu   +10 more
doaj   +1 more source

Mixed Segregation of Chromosomes During Single-division Meiosis of Saccharomyces Cerevisiae [PDF]

, 1991
G Sharon, G Simchen
openalex   +1 more source

The ParB-parS Chromosome Segregation System Modulates Competence Development in Streptococcus pneumoniae

mBio, 2015
ParB proteins bind centromere-like DNA sequences called parS sites and are involved in plasmid and chromosome segregation in bacteria. We previously showed that the opportunistic human pathogen Streptococcus pneumoniae contains four parS sequences ...
L. Attaiech, A. Minnen, Morten Kjos, S. Gruber, J. Veening   +4 more
semanticscholar   +1 more source

Chromosome Segregation [PDF]

Developmental Cell, 2002
Weitzer, Stefan, Uhlmann, Frank
openaire   +1 more source

Clinical Presentation of the Longest Reported Living Individual With Bent Bone Dysplasia—FGFR2‐Related

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The FGFR2 gene, encoding the FGFR2 protein, plays a crucial role in embryonic cell development, particularly in bone tissue. Bent Bone Dysplasia (BBD), FGFR2‐related (MIM# 614592), is a rare severe skeletal dysplasia characterized by craniofacial differences, reduced bone mineral density, and bowed long bones.
Cheyenne Bates, Pardeep Gill, Matthew Choi, Frances Mahon, Blake Yarascavitch, Audrey Lim, Resham Ejaz   +6 more
wiley   +1 more source

UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer

Molecular & Cellular Oncology, 2018
Defects in mitosis can lead to aneuploidy, which is a common feature of human cancers. Spindle Assembly Checkpoint (SAC) controls fidelity of chromosome segregation in mitosis to prevent aneuploidy. The ubiquitin receptor protein Ubiquitin Associated and
Ksenia Krupina, Charlotte Kleiss, Sushil Awal, Irene Rodriguez-Hernandez, Victoria Sanz-Moreno, Izabela Sumara   +5 more
doaj   +1 more source

Temporally correlated active forces drive segregation and enhanced dynamics in chromosome polymers [PDF]

, 2023
Sumitabha Brahmachari, Tomer Markovich, F. C. MacKintosh, José N. Onuchic   +3 more
openalex   +1 more source

Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage [PDF]

, 1994
The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction.
Al-Harithy, R, Carr, A M, Lehmann, A R, Murray, J M, Sheldrick, K S, Tavassoli, M, Watts, F Z   +6 more
core   +1 more source

Genotypes and Phenotypes of Patients With TSPEAR‐Related Disorder: Evidence of a Predominant Dental Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani, Lucia Tiberi, Annarita Giliberti, Elia Dirupo, Laila Zaroili, Francesco Brancati, Michela Brena, Stefano Caraffi, Chiara De Luca, Livia Garavelli, Anna Virginia Gulino, Milena Mariani, Marzia Pollazzon, Angelo Selicorni, Samuela Landini, Ilaria Sani, Rosangela Artuso, Angela Peron   +17 more
wiley   +1 more source

RNAi pathway participates in chromosome segregation in mammalian cells

Cell Discovery, 2015
The RNAi machinery is a mighty regulator in a myriad of life events. Despite lines of evidence that small RNAs and components of the RNAi pathway may be associated with structure and behavior of mitotic chromosomes in diverse organisms, a direct role of ...
Chuan Huang, Xiaolin Wang, Xu Liu, Shuhuan Cao, G. Shan   +4 more
semanticscholar   +1 more source