Results 171 to 180 of about 616,821 (255)

Fine mapping of cucumber downy mildew resistance loci identifies candidate genes linked to ethylene‐associated stomatal defence

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Downy mildew, caused by Pseudoperonospora cubensis, is one of the most destructive diseases affecting cucumber and remains difficult to manage sustainably through fungicide‐dependent control strategies. Although several resistance loci have been reported, many previously mapped regions remain too broad for efficient marker‐assisted ...
Mahdi Badri Anarjan   +8 more
wiley   +1 more source

Author Correction: An extrinsic motor directs chromatin loop formation by cohesin

open access: yesThe EMBO Journal
Thomas M Guérin   +4 more
doaj   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu   +4 more
wiley   +1 more source

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño   +6 more
wiley   +1 more source

Protein Glutamylation: From Cytoskeleton to Signaling

open access: yesMed Research, EarlyView.
Tubulin glutamylation, γ‐glutamylation, and nontubulin glutamylation are distinct yet interconnected post‐translational modifications that regulate diverse physiological and pathological processes, including cytoskeletal organization, cell cycle progression, immunity, metabolism, and disease development.
Jiayuan Chen   +4 more
wiley   +1 more source

DNAJC13 Variants Show No Robust Association With Parkinson's Disease in a Multiancestry Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background DNAJC13 was initially linked to autosomal dominant (AD) Parkinson's disease (PD) in a European Mennonite family carrying the p.N855S variant. However, imperfect segregation and conflicting reports of pathogenicity raised uncertainty of the role of DNAJC13 in the disease.
César Luis Ávila   +11 more
wiley   +1 more source

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