Results 311 to 320 of about 178,125 (345)
Some of the next articles are maybe not open access.
Plasmid and chromosome segregation in prokaryotes
Trends in Microbiology, 2000Recent major advances in the understanding of prokaryotic DNA segregation have been achieved by using fluorescence microscopy to visualize the localization of cellular components. Plasmids and bacterial chromosomes are partitioned in a highly dynamic fashion, suggesting the presence of a mitotic-like apparatus in prokaryotes.
Møller-Jensen, Jakob +2 more
openaire +4 more sources
Chromosome segregation and genomic stability
Current Opinion in Genetics & Development, 2004The acquisition of genomic instability is a crucial step in the development of human cancer. Genomic instability has multiple causes of which chromosomal instability (CIN) and microsatellite instability (MIN) have received the most attention. Whereas the connection between a MIN phenotype and cancer is now proven, the argument that CIN causes cancer ...
Peter K. Sorger +2 more
openaire +3 more sources
Mechanisms for Chromosome and Plasmid Segregation
Annual Review of Biochemistry, 2006The fundamental problems in duplicating and transmitting genetic information posed by the geometric and topological features of DNA, combined with its large size, are qualitatively similar for prokaryotic and eukaryotic chromosomes. The evolutionary solutions to these problems reveal common themes.
Sujata Hajra +3 more
openaire +3 more sources
Segregation of the Bacterial Chromosome
1998Bacteria must successfully complete several processes of the cell cycle to ensure that a single cell will become two viable daughter cells. These processes include: 1) replication of the chromosome, 2) segregation of the chromosomes to opposite poles, and 3) cell division.
Robert A. Britton, James R. Lupski
openaire +2 more sources
Chromosome Replication and Segregation
2014This chapter reviews our current understanding of bacterial DNA replication and chromosome partitioning in Bacillus subtilis and makes comparisons to Escherichia coli and other organisms where appropriate. Bacterial chromosome replication initiates once per cell division cycle in response to a signal that is tightly coupled to cell mass.
Katherine P. Lemon +3 more
openaire +2 more sources
Ubiquitin, the centrosome, and chromosome segregation
Chromosome Research, 2015For over a century, the abnormal movement or number of centrosomes has been linked with errors of chromosomes distribution in mitosis. While not essential for the formation of the mitotic spindle, the presence and location of centrosomes has a major influence on the manner in which microtubules interact with the kinetochores of replicated sister ...
Ying Zhang, Paul J. Galardy
openaire +3 more sources
Chromosome Cohesion and Segregation
2004Eukaryotic cells have multiple chromosomes as carts for the genetic information. In order to ensure faithful reproduction for proliferation in mitosis, or providing an opportunity for genetic reassortment in meiosis, cells must have the ability to deliver their chromosomes properly and in good order to the daughter cells.
Mitsuhiro Yanagida, Kohta Takahashi
openaire +2 more sources
The role of SUMO in chromosome segregation
Chromosoma, 2006Chromosome segregation is an essential feature of the eukaryotic cell cycle. Efficient chromosome segregation requires the co-ordination of several cellular processes; some of which involve gross rearrangements of the overall structure of the genetic material.
openaire +3 more sources
Chromosome segregation and cytokinesis in bacteria
Current Opinion in Cell Biology, 1993Substantial progress has recently been made in the understanding of chromosome partitioning and cytokinesis in bacteria. The biochemical properties of some key protein components involved in these processes are beginning to emerge. New evidence supports the recently developed notion that, in prokaryotic cells, basic cell biological processes rely on ...
openaire +3 more sources
Chromosome Segregation and Aneuploidy
1993Of all genetic afflictions of man, aneuploidy ranks as the most prevalent. Among liveborn babies aneuploidy exist to the extent of about 0.3%, to about 5% among stillborns and a dramatic 25% among miscarriages. The burden is too heavy to be taken lightly.
openaire +2 more sources