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Coordinating Chromosome Segregation
Science, 2002The centrosomes provide organizing centers for the formation of the mitotic spindle and are thus critical for proper chromosome segregation during cell division. Matsumoto and Maller (see the Perspective by Arlot-Bonnemains and Prigent) studied the control of centrosome duplication in an in vitro system derived from Xenopus
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Chromosome segregation and genomic stability
Current Opinion in Genetics & Development, 2004The acquisition of genomic instability is a crucial step in the development of human cancer. Genomic instability has multiple causes of which chromosomal instability (CIN) and microsatellite instability (MIN) have received the most attention. Whereas the connection between a MIN phenotype and cancer is now proven, the argument that CIN causes cancer ...
Viji M, Draviam +2 more
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Regulating chromosome segregation
Nature Reviews Molecular Cell Biology, 2014openaire +1 more source

