Results 311 to 320 of about 1,021,502 (366)

Suppression of chromosome segregation defects of Escherichia coli muk mutants by mutations in topoisomerase I

, 2000
James A. Sawitzke, Stuart Austin
openalex   +1 more source

Canonical and Non‐Canonical Functions of Histone H3K4 Methylation Modifiers in Cancer

Cancer Science, EarlyView.
Histone H3K4‐modifying enzymes regulate gene expression and cellular processes critical to cancer development. Beyond their canonical roles, these enzymes also exhibit non‐catalytic and non‐histone functions, offering new opportunities for therapeutic intervention. ABSTRACT Histone H3K4 modifications are altered in the regulation of gene expression and
Takayuki Hoshii
wiley   +1 more source

PLK1 phosphorylation of ZW10 guides accurate chromosome segregation in mitosis. [PDF]

J Mol Cell Biol
Bellah SF, Xiong F, Dou Z, Yang F, Liu X, Yao X, Gao X, Zhang L.   +7 more
europepmc   +1 more source

Nonrandom Segregation of the Mouse Univalent X Chromosome: Evidence of Spindle-Mediated Meiotic Drive

, 2000
Renée LeMaire-Adkins, Patricia A. Hunt
openalex   +2 more sources

The Impact of Polyploid Giant Cancer Cells: The Root of Stress Resilience

Cancer Science, EarlyView.
Among the diverse characteristics of polyploid giant cancer cells (PGCCs) observed in various contexts, stress resilience is one of their key features, enabling survival and adaptation under harsh conditions. This review discusses the unique stress tolerance mechanisms of PGCCs and their implications for cancer progression, therapy resistance, and ...
Yuta Ogawa, Lydia Fisher, Tomonori Matsumoto   +2 more
wiley   +1 more source

Chromosome segregation of human nonhomologous Robertsonian translocations: insights from preimplantation genetic testing. [PDF]

Eur J Hum Genet
Benn P, Merrion K.
europepmc   +1 more source

Deletion of the Mis12C‐Binding Domain of CENP‐C Promotes Chromosomal Aneuploidy in Cutaneous Squamous Cell Carcinoma

Cancer Science, EarlyView.
M12BD deficiency increases a chromosomal aneuploidy, particularly trisomy of chromosomes 6 and 10. ABSTRACT CENP‐C, an essential component of the kinetochore, connects centromeric chromatin to the outer kinetochore, and thereby ensures accurate chromosome segregation.
Megumi Saito, Kazuhiro Okumura, Yurika Tokunaga, Sora Tanaka, Keisuke Otoyama, Yoshinori Hasegawa, Masatoshi Hara, Masakazu Hashimoto, Toshihiko Fujimori, Tatsuo Fukagawa, Yuichi Wakabayashi   +10 more
wiley   +1 more source

Chromosome segregation dynamics during the cell cycle of Staphylococcus aureus

Izquierdo-Martinez A, Schäper S, Brito AD, Liao Q, Tesseur C, Sorg M, Botinas DS, Wang X, Pinho MG.   +8 more
europepmc   +1 more source

Low-intensity pulsed ultrasound induces multifaced alterations in chromosome segregation, cytoskeletal filaments and cell junctions. [PDF]

Sci Rep
Udroiu I, Todaro F, Vitaliti A, Palmieri D, Guida E, Perilli G, Duranti L, D'Ottavi C, Mattei M, Dolci S, Paradossi G, Bedini A, Silvestri I, Sgura A, Domenici F.   +14 more
europepmc   +1 more source

Six New Cases of 22q13.2 Gain Including TFC20: First Report of Triplication and Smallest Duplication Associated With Neurodevelopmental Delays

Clinical Genetics, EarlyView.
This study reports six new cases of 22q13.2 duplication and triplication, including the TCF20 gene, associated with neurodevelopmental disorders and various morphological and systemic abnormalities. The findings suggest a variable expressivity, but their complete penetrance remains uncertain compared to well‐established loss‐of‐function variants ...
Etienne Bizot, Dima Jouni, Caroline Rooryck, Juliet Taylor, Marine Legendre, Lorelei Charbonnier, Julia Metreau, Emmanuelle Benaloun, Audrey Pinson, Geneviève Quenum, Jérôme Bouligand, Gérard Tachdjian, Philippe Labrune, Lucie Tosca   +13 more
wiley   +1 more source