Results 31 to 40 of about 74,687 (303)

Multiscale Dynamic Structuring of Bacterial Chromosomes

, 2021
International audienceSince the nucleoid was isolated from bacteria in the 1970s, two fundamental questions emerged and are still in the spotlight: how bacteria organize their chromosomes to fit inside the cell and how nucleoid organization enables ...
Junier, Ivan, Boccard, Frédéric, Lioy, Virginia   +2 more
core   +1 more source

Spatial organization of bacterial chromosomes [PDF]

Current Opinion in Microbiology, 2014
Bacterial chromosomes are organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells. Two distinct spatial patterns were described almost a decade ago in our most tractable model organisms. In recent years, analysis of chromosome organization in a larger and more diverse set of bacteria and a deeper ...
Xindan, Wang, David Z, Rudner
openaire   +2 more sources

Optical mapping as a routine tool for bacterial genome sequence finishing [PDF]

, 2007
Background: In sequencing the genomes of two Xenorhabdus species, we encountered a large number of sequence repeats and assembly anomalies that stalled finishing efforts.
Norton, S., Miller, N., Zijin Du, Goldman, Barry S., Latreille Phil, Bode, Helge Björn, Henkhaus John, Forst, Steve, John Henkhaus, Goodrich-Blair, H., Miller, Nancy, Slater Steven, Stacie Norton, Bode, H., Goldman Barry S, Henkhaus, J., Gaudriault, S., Steve Forst, Creg Darby, Gaudriault Sophie, Darby Creg, Goldman, B., Gaudriault, Sophie, Darby, C., Du, Z., Goodner, B., Norton, Stacie, Sophie Gaudriault, Miller Nancy, Goodrich-Blair, Heidi, Henkhaus, John, Heidi Goodrich-Blair, Gaudriault, Sophie, S., Latreille, Phil, Slater, S., Goodrich-Blair Heidi, Goodner, Brad, Goodner Brad, Latreille, P., Bode, Helge B., Nancy Miller, Norton Stacie, Brad Barbazuk, Phil Latreille, Steven Slater, Slater, Steven, Forst Steve, Helge B Bode, Forst, S., Barbazuk, Brad, Barbazuk Brad, Du, Zijin, Bode Helge B, Barry S Goldman, Du Zijin, Brad Goodner, Barbazuk, B., Darby, Creg   +57 more
core   +1 more source

A decade of antimicrobial resistance in Vibrio spp.: genomic and functional insights

Microbiology Spectrum
Environmental pressures and repeated exposure to antimicrobials drive microbial evolution, often through genomic changes or acquisition of mobile genetic elements that enhance fitness and resistance. This has critically influenced the control of cholera,
Agila Kumari Pragasam, Chandana Basak, Mansi Rajwanshi, Lekshmi Narendrakumar, Goutam Chowdhury, Prabhakar Babele, Meenal Chawla, Orlando Moranchel, Upma Singh, Deboleena Roy, Pradipta Jana, Tanshi Mehrotra, Debaleena Das, Daizee Talukdar, Deepjyoti Paul, Rupak K. Bhadra, Thandavarayan Ramamurthy, Amit Ghosh, Shanta Dutta, Christophe Possoz, François-Xavier Barre, Asish K. Mukhopadhyay, Bhabatosh Das   +22 more
doaj   +1 more source

Distribution of mononucleotide repeats in bacterial chromosomes: A/T-tracts dominate on G/C-tracts [PDF]

Компьютерные исследования и моделирование, 2010
This study analyzes the abundance of mononucleotide tracts of different length in 342 eubacterial and 69 archaeal chromosomes. Despite the fact that the amount of analyzed repeats depends on nucleotide content, the predominance of poly(dA)n- and poly(dT ...
Sergey Sergeevich Kisselev, Vladislav Mikhailovich Komarov, Irina Stanislavovna Masulis, Olga Nikolaevna Ozoline   +3 more
doaj   +1 more source

Bacterial chromosome extraction and isolation [PDF]

Lab on a Chip, 2002
We have used diffusive mixing and dielectrophoretic trapping to lyse Escherichia coli cells in a microfabricated environment and trap the E. coli chromosome. We characterize the conditions needed for efficient lysis of the cells, and conditions needed for the dielectrophoretic trapping of the chromatin without the trapping of cytoplasmic proteins.
Christelle, Prinz, Jonas O, Tegenfeldt, Robert H, Austin, Edward C, Cox, James C, Sturm   +4 more
openaire   +2 more sources

Bacterial Chromosome Organization and Segregation [PDF]

Cold Spring Harbor Perspectives in Biology, 2010
Bacterial chromosomes are generally approximately 1000 times longer than the cells in which they reside, and concurrent replication, segregation, and transcription/translation of this crowded mass of DNA poses a challenging organizational problem. Recent advances in cell-imaging technology with subdiffraction resolution have revealed that the bacterial
Esteban, Toro, Lucy, Shapiro
openaire   +2 more sources

The coevolution of toxin and antitoxin genes drives the dynamics of bacterial addiction complexes and intragenomic conflict [PDF]

, 2012
Bacterial genomes commonly contain 'addiction' gene complexes that code for both a toxin and a corresponding antitoxin. As long as both genes are expressed, cells carrying the complex can remain healthy.
Rankin, Daniel J., Leighton A. Turner, Daniel J. Rankin, Heinemann, Jack A., Brown, Sam P., Sam P. Brown, Turner, Leighton A., Jack A. Heinemann   +7 more
core   +1 more source

Mechanisms for Chromosome Segregation in Bacteria

Frontiers in Microbiology, 2021
The process of DNA segregation, the redistribution of newly replicated genomic material to daughter cells, is a crucial step in the life cycle of all living systems.
Christos Gogou, Aleksandre Japaridze, Cees Dekker   +2 more
doaj   +1 more source

Bacterial Chromosome Organization and Segregation [PDF]

Annual Review of Cell and Developmental Biology, 2015
If fully stretched out, a typical bacterial chromosome would be nearly 1 mm long, approximately 1,000 times the length of a cell. Not only must cells massively compact their genetic material, but they must also organize their DNA in a manner that is compatible with a range of cellular processes, including DNA replication, DNA repair, homologous ...
Badrinarayanan, Anjana, Le, Tung, Laub, Michael T   +2 more
openaire   +4 more sources