Results 31 to 40 of about 1,037,337 (302)

Bacterial Chromosome Organization and Segregation [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2010
Bacterial chromosomes are generally approximately 1000 times longer than the cells in which they reside, and concurrent replication, segregation, and transcription/translation of this crowded mass of DNA poses a challenging organizational problem. Recent advances in cell-imaging technology with subdiffraction resolution have revealed that the bacterial
Esteban, Toro, Lucy, Shapiro
openaire   +2 more sources

Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes [PDF]

open access: yes, 2010
Copyright: © 2010 Stimpson et al.Genome rearrangement often produces chromosomes with two centromeres (dicentrics) that are inherently unstable because of bridge formation and breakage during cell division. However, mammalian dicentrics, and particularly
Sullivan, Beth A.   +35 more
core   +2 more sources

Replisome Assembly at Bacterial Chromosomes and Iteron Plasmids

open access: yesFrontiers in Molecular Biosciences, 2016
The proper initiation and occurrence of DNA synthesis depends on the formation and rearrangements of nucleoprotein complexes within the origin of DNA replication.
Katarzyna Ewa Wegrzyn   +3 more
doaj   +1 more source

Bacterial chromosome segregation

open access: yesFrontiers in Bioscience, 2012
Dividing cells have mechanisms to ensure that their genomes are faithfully segregated into daughter cells. In bacteria, the description of these mechanisms has been considerably improved in the recent years. This review focuses on the different aspects of bacterial chromosome segregation that can be understood thanks to the studies performed with model
Christophe, Possoz   +2 more
openaire   +3 more sources

Karyotyping human chromosomes by optical and X-ray ptychography methods [PDF]

open access: yes, 2014
Sorting and identifying chromosomes, a process known as karyotyping, is widely used to detect changes in chromosome shapes and gene positions. In a karyotype the chromosomes are identified by their size and therefore this process can be performed by ...
Xiong, G   +18 more
core   +1 more source

Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains [PDF]

open access: yes, 2012
The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3.
Elizabeth Schroeder-Reiter   +35 more
core   +2 more sources

Bacteria spring a surprise [PDF]

open access: yes, 2014
Cell division involves the precise duplication of all the genetic material in the cell—both the chromosomes and the plasmid DNA—and the equal division of this material between the two daughter cells.
Srinivasan, Rajagopalan   +3 more
core   +1 more source

Molecular basis for SMC rod formation and its dissolution upon DNA binding. [PDF]

open access: yes, 2015
SMC condensin complexes are central modulators of chromosome superstructure in all branches of life. Their SMC subunits form a long intramolecular coiled coil, which connects a constitutive "hinge" dimerization domain with an ATP-regulated "head ...
Soh, Young-Min   +69 more
core   +1 more source

Non-random chromosome positioning in mammalian sperm nuclei, with migration of the sex chromosomes during late spermatogenesis. [PDF]

open access: yes, 2005
Chromosomes are highly organized and compartmentalized in cell nuclei. The analysis of their position is a powerful way to monitor genome organization in different cell types and states.
Foster, H   +7 more
core   +1 more source

Modeling meiotic chromosomes indicates a size dependent contribution of telomere clustering and chromosome rigidity to homologue juxtaposition [PDF]

open access: yes, 2012
Meiosis is the cell division that halves the genetic component of diploid cells to form gametes or spores. To achieve this, meiotic cells undergo a radical spatial reorganisation of chromosomes.
Penfold, Christopher A.   +19 more
core   +2 more sources

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