Results 71 to 80 of about 145,292 (281)

Sequencing of 15 622 Gene-bearing BACs Clarifies the Gene-dense Regions of the Barley Genome [PDF]

, 2015
Barley (Hordeum vulgare L.) possesses a large and highly repetitive genome of 5.1 Gb that has hindered the development of a complete sequence. In 2012, the International Barley Sequencing Consortium released a resource integrating whole-genome shotgun ...
Alpert, Matthew, Altschmied, Lothar, Beccuti, Marco, Bhat, Prasanna R., Blake, Tom, Bozdag, Serdar, Bregitzer, Phil, Chao, Shiaoman, Close, Timothy J., Condamine, Pascal, Cooper, Laurel, Cordero, Francesca, Dilbirligi, Muharrem, Dolezel, Jaroslav, Duma, Denisa, Falk, Anders, Feiz, Leila, Graner, Andreas, Grimwood, Jane, Gustafson, Perry, Hayes, Patrick M., Heinen, Shane, Jiang, Tao, Kleinhofs, Andris, Kudrna, Dave, Lemaux, Peggy, Lonardi, Stefano, Luo, MingCheng, Ma, Shane, Madishetty, Kavitha, Mammadov, Jafar, Mirebrahim, Hamid, Moscou, Matthew J., Muehlbauer, Gary J., Muñoz-Amatriaín, María, Ounit, Rachid, Resnik, Josh, Rodriguez, Edmundo, Schmutz, Jeremy, Simková, Hana, Stein, Nils, Svensson, Jan T., Wanamaker, Steve, Wing, Rod, Wise, Roger P., Witt, Heather N., Wu, Yonghui, You, Frank, Zheng, Jie   +48 more
core   +2 more sources

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

FRUIT, a scar-free system for targeted chromosomal mutagenesis, epitope tagging, and promoter replacement in Escherichia coli and Salmonella enterica. [PDF]

PLoS ONE, 2012
Recombineering is a widely-used approach to delete genes, introduce insertions and point mutations, and introduce epitope tags into bacterial chromosomes. Many recombineering methods have been described, for a wide range of bacterial species.
Anne M Stringer, Navjot Singh, Anastasiya Yermakova, Brianna L Petrone, Jayaleka J Amarasinghe, Lucia Reyes-Diaz, Nicholas J Mantis, Joseph T Wade   +7 more
doaj   +1 more source

Synteny analysis in Rosids with a walnut physical map reveals slow genome evolution in long-lived woody perennials. [PDF]

, 2015
BackgroundMutations often accompany DNA replication. Since there may be fewer cell cycles per year in the germlines of long-lived than short-lived angiosperms, the genomes of long-lived angiosperms may be diverging more slowly than those of short-lived ...
Aradhya, Mallikarjuna, Dandekar, Abhaya M, Dvorak, Jan, Leslie, Charles A, Li, Pingchuan, Luo, Ming-Cheng, McGuire, Patrick E, Wang, Ji-Rui, You, Frank M, Zhu, Tingting   +9 more
core   +2 more sources

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective

Frontiers in Microbiology, 2018
Bacterial chromosomes have a single, unique replication origin (named oriC), from which DNA synthesis starts. This study describes methods of visualizing oriC regions and the chromosome replication in single living bacterial cells in real-time.
Damian Trojanowski, Joanna Hołówka, Jolanta Zakrzewska-Czerwińska   +2 more
doaj   +1 more source

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad, Ahmad, Ahn, Ahnesorg, Akamatsu, Assenmacher, Baumann, Boddy, Boddy, Bonatto, Bransteitter, Buck, Callebaut, Caspari, Catlett, Cervantes, Chahwan, Cheok, Connelly, Cooper, Doe, Doe, Doe, Doe, Dudasova, Farah, Farah, Ferreira, Ferreira, Fukushima, Gaillard, Goedecke, Goodwin, Grishchuk, Haber, Hartsuiker, Hefferin, Jang, Jung, Khasanov, Khasanov, Kibe, Kim, Kim, Krogh, Lambert, Laursen, Macris, Maftahi, Maftahi, Manolis, Marchetti, Martin, McGlynn, Moore, Morishita, Muris, Muris, Muris, Murray, Nakada, Nakamura, Oakley, Ono, Osman, Osman, Osman, Ostermann, Paques, Parker, Prudden, Sauvageau, Schmidt, Segurado, Shinohara, Smith, Steiner, Stewart, Sung, Suto, Szankasi, Szostak, Tarsounas, Tavassoli, Thacker, Tomita, Tomita, Tsutsui, Tsutsui, Ueno, van den Bosch, van den Bosch, Virgin, Virgin, Wang, Weterings, Whitby, Whitby, Wilson, Win, Win, You, Young   +102 more
core   +2 more sources

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Analysis of the SOS response of Vibrio and other bacteria with multiple chromosomes

BMC Genomics, 2012
Background The SOS response is a well-known regulatory network present in most bacteria and aimed at addressing DNA damage. It has also been linked extensively to stress-induced mutagenesis, virulence and the emergence and dissemination of antibiotic ...
Sanchez-Alberola Neus, Campoy Susana, Barbé Jordi, Erill Ivan   +3 more
doaj   +1 more source

High resolution physical mapping of single gene fragments on pachytene chromosome 4 and 7 of Rosa [PDF]

, 2015
Background: Rosaceae is a family containing many economically important fruit and ornamental species. Although fluorescence in situ hybridization (FISH)-based physical mapping of plant genomes is a valuable tool for map-based cloning, comparative ...
Khrustaleva, Ludmila I, Kirov, Ilya V, Van Laere, Katrijn   +2 more
core   +2 more sources