Results 11 to 20 of about 1,205,521 (283)

Chain organization of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci.

PLoS Computational Biology, 2018
We investigate spatiotemporal dynamics of human interphase chromosomes by employing a heteropolymer model that incorporates the information of human chromosomes inferred from Hi-C data.
Lei Liu, Guang Shi, D Thirumalai, Changbong Hyeon   +3 more
doaj   +2 more sources

Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]

, 1990
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas, Gezer, Sefer, Kolluri, Rukmini V., Manuelidis, L., Raza, Azra, Sait, Sheila   +5 more
core   +1 more source

Karyotypic features including organizations of the 5S, 45S rDNA loci and telomeres of Scadoxus multiflorus (Amaryllidaceae)

Comparative Cytogenetics, 2016
Scadoxus multiflorus Martyn, 1795 is an ornamental plant with brilliantly colored flowers. Even though its chromosomes are rather large, there is no karyotype description reported so far.
Pansa Monkheang, Arunrat Chaveerach, Runglawan Sudmoon, Tawatchai Tanee   +3 more
doaj   +3 more sources

Comparison of phasing strategies for whole human genomes. [PDF]

PLoS Genetics, 2018
Humans are a diploid species that inherit one set of chromosomes paternally and one homologous set of chromosomes maternally. Unfortunately, most human sequencing initiatives ignore this fact in that they do not directly delineate the nucleotide content ...
Yongwook Choi, Agnes P Chan, Ewen Kirkness, Amalio Telenti, Nicholas J Schork   +4 more
doaj   +1 more source

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries [PDF]

, 1988
A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported.
B Trask, C Cremer, D Pinkel, D Pinkel, D. C. Ward, DA Agard, DJ Brigati, DJ Finney, GA Rappold, GD Johnson, GJ Brakenhoff, H Hamada, HE McDermid, HJ Cooke, J. Borden, JE Landegent, JG White, JR Gosden, JS Waye, L Hens, L Manuelidis, L Manuelidis, L Manuelidis, L Manuelidis, L Manuelidis, L. Manuelidis, LG Davis, M Schardin, MA Dilla Van, ML Mendelsohn, P. Lichter, PG Sealey, PR Langer, RJ Britten, T Cremer, T Cremer, T Cremer, T Cremer, T Maniatis, T. Cremer   +39 more
core   +1 more source

Chromosome painting in three-toed sloths: a cytogenetic signature and ancestral karyotype for Xenarthra

BMC Evolutionary Biology, 2012
Background Xenarthra (sloths, armadillos and anteaters) represent one of four currently recognized Eutherian mammal supraorders. Some phylogenomic studies point to the possibility of Xenarthra being at the base of the Eutherian tree, together or not with
Azevedo Nathália F, Svartman Marta, Manchester Andrea, de Moraes-Barros Nádia, Stanyon Roscoe, Vianna-Morgante Angela M   +5 more
doaj   +1 more source

Characterization of an alpha 1—-3-galactosyltransferase homologue on human chromosome 12 that is organized as a processed pseudogene.

Journal of Biological Chemistry, 1991
UDP-Gal:Gal beta 1----4GlcNAc alpha 1----3-galactosyltransferase is a terminal glycosyltransferase that is widely expressed in a variety of mammalian species, with the notable exception of man, apes, and Old World monkeys. We recently reported the isolation of a bovine cDNA clone that contains the complete coding sequence for this enzyme (Joziasse, D ...
D H, Joziasse, J H, Shaper, E W, Jabs, N L, Shaper   +3 more
openaire   +2 more sources

Development of a Biological Dosimeter for Translocation Scoring Based on Two-Color Fluorescence in Situ Hybridization of Chromosome Subsets [PDF]

, 1992
Recently fluorescence in situ hybridization protocols have been developed which allow the paining of individual chromosomes using DNA-libraries from sorted human chromosomes.
Cremer, Thomas, Popp, Susanne
core   +1 more source

An Isochore Framework Underlies Chromatin Architecture. [PDF]

PLoS ONE, 2017
A recent investigation showed the existence of correlations between the architectural features of mammalian interphase chromosomes and the compositional properties of isochores.
Kamel Jabbari, Giorgio Bernardi
doaj   +1 more source

Chimpanzee and Human Y Chromosomes Are Remarkably Divergent in Structure and Gene Content [PDF]

, 2009
LetterThe human Y chromosome began to evolve from an autosome hundreds of millions of years ago, acquiring a sex-determining function and undergoing a series of inversions that suppressed crossing over with the X chromosome[1, 2].
AF Dixson, B Charlesworth, B Charlesworth, Barbara J. Trask, BT Lahn, CL Peichel, CT Yohn, Cynthia Friedman, D Bachtrog, D Bachtrog, DA Filatov, David C. Page, DC Page, Devin P. Locke, Elaine R. Mardis, H Skaletsky, H Watanabe, HC Mefford, Helen Skaletsky, J Lange, Jennifer F. Hughes, JF Hughes, JF Hughes, LW Hillier, Patrick J. Minx, R Saxena, RF Yeh, Richard K. Wilson, Robert S. Fulton, S Repping, S Repping, S Repping, S Rozen, S Steinemann, Saskia K. M. van Daalen, Sean D. McGrath, Sjoerd Repping, Steve Rozen, T Kuroda-Kawaguchi, Tatyana Pyntikova, Tina A. Graves, Wesley C. Warren, WJ Murphy, WR Rice, Y Kuroki, Z Liu   +45 more
core   +1 more source