Results 11 to 20 of about 419,615 (160)

Chromosome painting in three-toed sloths: a cytogenetic signature and ancestral karyotype for Xenarthra

BMC Evolutionary Biology, 2012
Background Xenarthra (sloths, armadillos and anteaters) represent one of four currently recognized Eutherian mammal supraorders. Some phylogenomic studies point to the possibility of Xenarthra being at the base of the Eutherian tree, together or not with
Azevedo Nathália F, Svartman Marta, Manchester Andrea, de Moraes-Barros Nádia, Stanyon Roscoe, Vianna-Morgante Angela M   +5 more
doaj   +1 more source

Comparison of phasing strategies for whole human genomes. [PDF]

PLoS Genetics, 2018
Humans are a diploid species that inherit one set of chromosomes paternally and one homologous set of chromosomes maternally. Unfortunately, most human sequencing initiatives ignore this fact in that they do not directly delineate the nucleotide content ...
Yongwook Choi, Agnes P Chan, Ewen Kirkness, Amalio Telenti, Nicholas J Schork   +4 more
doaj   +1 more source

Genetic Influence on Frequencies of Myeloid-Derived Cell Subpopulations in Mouse

Frontiers in Immunology, 2022
Differences in frequencies of blood cell subpopulations were reported to influence the course of infections, atopic and autoimmune diseases, and cancer.
Imtissal Krayem, Yahya Sohrabi, Eliška Javorková, Eliška Javorková, Valeriya Volkova, Hynek Strnad, Helena Havelková, Jarmila Vojtíšková, Aigerim Aidarova, Vladimír Holáň, Vladimír Holáň, Peter Demant, Marie Lipoldová   +12 more
doaj   +1 more source

Development of a Biological Dosimeter for Translocation Scoring Based on Two-Color Fluorescence in Situ Hybridization of Chromosome Subsets [PDF]

, 1992
Recently fluorescence in situ hybridization protocols have been developed which allow the paining of individual chromosomes using DNA-libraries from sorted human chromosomes.
Cremer, Thomas, Popp, Susanne
core   +1 more source

Chimpanzee and Human Y Chromosomes Are Remarkably Divergent in Structure and Gene Content [PDF]

, 2009
LetterThe human Y chromosome began to evolve from an autosome hundreds of millions of years ago, acquiring a sex-determining function and undergoing a series of inversions that suppressed crossing over with the X chromosome[1, 2].
AF Dixson, B Charlesworth, B Charlesworth, Barbara J. Trask, BT Lahn, CL Peichel, CT Yohn, Cynthia Friedman, D Bachtrog, D Bachtrog, DA Filatov, David C. Page, DC Page, Devin P. Locke, Elaine R. Mardis, H Skaletsky, H Watanabe, HC Mefford, Helen Skaletsky, J Lange, Jennifer F. Hughes, JF Hughes, JF Hughes, LW Hillier, Patrick J. Minx, R Saxena, RF Yeh, Richard K. Wilson, Robert S. Fulton, S Repping, S Repping, S Repping, S Rozen, S Steinemann, Saskia K. M. van Daalen, Sean D. McGrath, Sjoerd Repping, Steve Rozen, T Kuroda-Kawaguchi, Tatyana Pyntikova, Tina A. Graves, Wesley C. Warren, WJ Murphy, WR Rice, Y Kuroki, Z Liu   +45 more
core   +1 more source

An Isochore Framework Underlies Chromatin Architecture. [PDF]

PLoS ONE, 2017
A recent investigation showed the existence of correlations between the architectural features of mammalian interphase chromosomes and the compositional properties of isochores.
Kamel Jabbari, Giorgio Bernardi
doaj   +1 more source

In silico identification of potential inhibitors for human aurora kinase b [PDF]

, 2007
Cell cycle progression through mitosis and meiosis involves regulation by serine/threonine kinases from the aurora family. Aurora kinase b (Aurkb) is mainly involved in the proper segregation of chromosomes during mitosis as well as meiosis.
Amineni Umamaheswari, Dibyabhaba Pradhan, Mahesh Babu G, Manne MuniKumar, Pradeep N.   +4 more
core   +2 more sources

Natural Loss of Mps1 Kinase in Nematodes Uncovers a Role for Polo-like Kinase 1 in Spindle Checkpoint Initiation

Cell Reports, 2015
The spindle checkpoint safeguards against chromosome loss during cell division by preventing anaphase onset until all chromosomes are attached to spindle microtubules.
Julien Espeut, Pablo Lara-Gonzalez, Mélanie Sassine, Andrew K. Shiau, Arshad Desai, Ariane Abrieu   +5 more
doaj   +1 more source

Histone H3K9 and H4 Acetylations and Transcription Facilitate the Initial CENP-AHCP−3 Deposition and De Novo Centromere Establishment in Caenorhabditis elegans Artificial Chromosomes

Epigenetics & Chromatin, 2018
Background The centromere is the specialized chromatin region that directs chromosome segregation. The kinetochore assembles on the centromere, attaching chromosomes to microtubules in mitosis.
Jing Zhu, Kevin Chi Lok Cheng, Karen Wing Yee Yuen   +2 more
doaj   +1 more source

Characterization of two marker chromosomes in a patient with acute nonlymphocytic leukemia by two-color fluorescence in situ hybridization [PDF]

, 1993
A patient with acute nonlymphocytic leukemia (ANLL), M5b according to French-American-British (FAB) classification, showed monosomy 16, an extra 1p−, and a 21q+. These derivative chromosomes could not be defined by GTG-banding.
Anna Jauch, Brothman, Burke, Christoph Lengauer, Collins, Cooke, Cremer, Cremer, Jauch, Klever, Lengauer, Lengauer, Lengauer, Lichter, Lichter, Marosi, Masafumi Taniwaki, Michael R. Speicher, Moyzis, Pinkel, Pinkel, Rowley, Selleri, Smit, Speleman, Susanne Popp, Thomas Cremer   +26 more
core   +1 more source