Results 51 to 60 of about 1,205,521 (283)
Nucleotide Frequencies in Human Genome and Fibonacci Numbers [PDF]
, 2006 This work presents a mathematical model that establishes an interesting connection between nucleotide frequencies in human single-stranded DNA and the famous Fibonacci's numbers. The model relies on two assumptions.
A. Dress +14 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Additional haplogroups of Toxoplasma gondii out of Africa: population structure and mouse-virulence of strains from Gabon. [PDF]
PLoS Neglected Tropical Diseases, 2010 BACKGROUND: Toxoplasma gondii is found worldwide, but distribution of its genotypes as well as clinical expression of human toxoplasmosis varies across the continents.
Aurélien Mercier +8 more
doaj +1 more source
Using Nanopore Sequencing to Obtain Complete Bacterial Genomes from Saliva Samples
mSystems, 2022 Obtaining complete, high-quality reference genomes is essential to the study of any organism. Recent advances in nanopore sequencing, as well as genome assembly and analysis methods, have made it possible to obtain complete bacterial genomes from ...
Jonathon L. Baker
doaj +1 more source
A role for Separase in telomere protection [PDF]
, 2016 Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity and are assembled independently of the sequence. Fly telomeres are protected by the terminin complex that localizes and functions exclusively
Bosso, Giuseppe +9 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Apoptosis in mouse fetal and neonatal oocytes during meiotic prophase one [PDF]
, 2007 Background The vast majority of oocytes formed in the fetal ovary do not survive beyond birth. Possible reasons for their loss include the elimination of non-viable genetic constitutions arising through meiosis, however, the ...
Ghafari , Fataneh +2 more
core +4 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
An insight into the phylogenetic history of
BMC Evolutionary Biology, 2007 Background The human chromosomes 2q, 7, 12q and 17q show extensive intra-genomic homology, containing duplicate, triplicate and quadruplicate paralogous regions centered on the HOX gene clusters.
Grzeschik Karl-Heinz, Abbasi Amir
doaj +1 more source
Genomics of an ancient sex chromosome in Tilapia. W633 [PDF]
, 2012 We have developed important genomic tools and methods of comparative genomics in the Nile tilapia, Oreochromis niloticus. The physical comparative map generated with BACs allowed us to calculate that there were about one rearrangement of intra ...
Baroiller, Jean-François +7 more
core