Results 11 to 20 of about 186,243 (242)

Deep ancestry of mammalian X chromosome revealed by comparison with the basal tetrapod Xenopus tropicalis

BMC Genomics, 2012
Background The X and Y sex chromosomes are conspicuous features of placental mammal genomes. Mammalian sex chromosomes arose from an ordinary pair of autosomes after the proto-Y acquired a male-determining gene and degenerated due to suppression of X-Y ...
Mácha Jaroslav, Teichmanová Radka, Sater Amy K, Wells Dan E, Tlapáková Tereza, Zimmerman Lyle B, Krylov Vladimír   +6 more
doaj   +1 more source

Chromosome-specific alpha satellite DNA from human chromosome 1: Hierarchical structure and genomic organization of a polymorphic domain spanning several hundred kilobase pairs of centromeric DNA

Genomics, 1987
The human alpha satellite repetitive DNA family is organized as distinct chromosome-specific subsets localized to the centromeric region of each chromosome. Here, we report he isolation and characterization of cloned repeat units which define a hierarchical subset of alpha satellite on human chromosome 1. This subset is characterized by a 1.9-kb higher-
J S, Waye, S J, Durfy, D, Pinkel, S, Kenwrick, M, Patterson, K E, Davies, H F, Willard   +6 more
openaire   +2 more sources

Large-scale reconstruction of 3D structures of human chromosomes from chromosomal contact data

Nucleic Acids Research, 2014
Chromosomes are not positioned randomly within a nucleus, but instead, they adopt preferred spatial conformations to facilitate necessary long-range gene–gene interactions and regulations.
Tuan Trieu, Jianlin Cheng
semanticscholar   +1 more source

Data supporting the design and evaluation of a universal primer pair for pseudogene-free amplification of HPRT1 in real-time PCR

Data in Brief, 2015
Hypoxanthine-guanine phosphoribosyltransferase 1 (HPRT1) is a common housekeeping gene for sample normalization in the quantitative reverse transcriptase polymerase chain (qRT-PCR).
Reza Valadan, Akbar Hedayatizadeh-Omran, Mahdyieh Naghavi Alhosseini-Abyazani, Omolbanin Amjadi, Alireza Rafiei, Mohsen Tehrani, Reza Alizadeh-Navaei   +6 more
doaj   +1 more source

Frequent gene conversion events between the X and Y homologous chromosomal regions in primates

BMC Evolutionary Biology, 2010
Background Mammalian sex-chromosomes originated from a pair of autosomes. A step-wise cessation of recombination is necessary for the proper maintenance of sex-determination and, consequently, generates a four strata structure on the X chromosome.
Hirai Hirohisa, Satta Yoko, Iwase Mineyo, Hirai Yuriko, Takahata Naoyuki   +4 more
doaj   +1 more source

Conformation of sister chromatids in the replicated human genome

Nature, 2020
The three-dimensional organization of the genome supports regulated gene expression, recombination, DNA repair, and chromosome segregation during mitosis.
Michael Mitter, Catherina Gasser, Zsuzsanna Takács, Christoph C. H. Langer, Wen Tang, Gregor Jessberger, Charlie T. Beales, Eva Neuner, Stefan L Ameres, J. Peters, A. Goloborodko, R. Micura, D. Gerlich   +12 more
semanticscholar   +1 more source

Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeats

Nature, 2023
Epstein–Barr Virus (EBV) nuclear antigen 1 is shown to induce breakage of a fragile site on chromosome 11 by binding to a cluster of EBV-like imperfect palindromic repeats.
J. S. Z. Li, Ammal Abbasi, D. H. Kim, S. Lippman, Ludmil B. Alexandrov, D. Cleveland   +5 more
semanticscholar   +1 more source

A comparative of G-banded chromosome of Assam Macaque (Macaca assamensis) and relationship to human (Homo sapiens) [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2006
This research was the first to report a comparative analysis of G-banded chromosome of Assam macaque, Macaca assamensis (Primate, Cercopithecidae) and relationship to human, Homo sapiens (Primate, Hominidae).
Bunjongrat, R., Khunsook, S., Kaensa, W., Tanomtong, A.   +3 more
doaj  

Identification of QTLs associated with cadmium concentration in rice grains

Journal of Integrative Agriculture, 2018
Cadmium (Cd) contamination in rice has been a hot topic of research because of its potential risk to human health. In this study, a double haploid (DH) population derived from Zhongjiazao 17 (YK17) (an early-season indica cultivar)×D50 (a tropical ...
Da-wei HU, Zhong-hua SHENG, Qian-long LI, Wei CHEN, Xiang-jin WEI, Li-hong XIE, Gui-ai JIAO, Gao-neng SHAO, Jian-long WANG, Shao-qing TANG, Pei-song HU   +10 more
doaj   +1 more source

Detection of fetal trisomy and single gene disease by massively parallel sequencing of extracellular vesicle DNA in maternal plasma: a proof-of-concept validation

BMC Medical Genomics, 2019
Background During human pregnancy, placental trophectoderm cells release extracellular vesicles (EVs) into maternal circulation. Trophoblasts also give rise to cell-free DNA (cfDNA) in maternal blood, and has been used for noninvasive prenatal screening ...
Weiting Zhang, Sen Lu, Dandan Pu, Haiping Zhang, Lin Yang, Peng Zeng, Fengxia Su, Zhichao Chen, Mei Guo, Ying Gu, Yanmei Luo, Huamei Hu, Yanping Lu, Fang Chen, Ya Gao   +14 more
doaj   +1 more source