Results 11 to 20 of about 83,934 (227)

Independent stratum formation on the avian sex chromosomes reveals inter-chromosomal gene conversion and predominance of purifying selection on the w chromosome [PDF]

, 2014
We used a comparative approach spanning three species and 90 million years to study the evolutionary history of the avian sex chromosomes. Using whole transcriptomes, we assembled the largest cross-species dataset of W-linked coding content to date.
Wright, Alison E, Harrison, Peter W, Mank, JE, Wright, AE, Montgomery, SH, Mank, Judith E, Pointer, Marie A, Harrison, PW, Pointer, MA, Montgomery, Stephen H   +9 more
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Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes [PDF]

, 1984
In situ hybridization experiments were carried out with two clones, YACG 35 and 2.8, which had been selected from two genomic libraries strongly enriched for the human Y chromosome.
Back, W., Cremer, Thomas, Rappold, Gudrun A., Cremer, Christoph, Bogenberger, J., Cooke, H. J.   +5 more
core   +1 more source

On the origin of crossover interference : a chromosome oscillatory movement (COM) model [PDF]

, 2011
Background: It is now nearly a century since it was first discovered that crossovers between homologous parental chromosomes, originating at the Prophase stage of Meiosis I, are not randomly placed.
Maj A Hultén, Hultén, Maj A., Hultén Maj A   +2 more
core   +1 more source

Thermodynamic pathways to genome spatial organization in the cell nucleus [PDF]

, 2009
The architecture of the eukaryotic genome is characterized by a high degree of spatial organization. Chromosomes occupy preferred territories correlated to their state of activity and, yet, displace their genes to interact with remote sites in complex ...
A. Prisco, Prisco, Antonella, Nicodemi, Mario   +2 more
core   +1 more source

Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells [PDF]

, 2013
Copyright © 2013 The Authors. This article is made available through the Brunel Open Access Publishing Fund. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which ...
Themis, M, Anderson, RM, Bridger, JM, Foster, HA, Estrada-Girona, G, Garimberti, E, Hill, MA   +6 more
core   +1 more source

Comparative BAC-based mapping in the white-throated sparrow, a novel behavioral genomics model, using interspecies overgo hybridization [PDF]

, 2011
BACKGROUND The genomics era has produced an arsenal of resources from sequenced organisms allowing researchers to target species that do not have comparable mapping and sequence information.
Tuttle, Elaina M, Michael N Romanov, Jerry B Dodgson, Dodgson, Jerry B, Tuttle Elaina M, Elaina M Tuttle, Romanov, Michael N, Dodgson Jerry B, Romanov Michael N, Gonser Rusty A, Rusty A Gonser, Gonser, Rusty A   +11 more
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Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes [PDF]

, 2011
The human X and Y chromosomes evolved from an ordinary pair of autosomes during the past 200–300 million years[superscript 1, 2, 3]. The human MSY (male-specific region of Y chromosome) retains only three percent of the ancestral autosomes’ genes owing ...
Tina Graves, Cree, Andrew, Villasana, Donna, Muzny, Donna M., Warren2, Wesley C., Graves, Tina, Christian J. Buhay, Donna Villasana, Richard A. Gibbs, Dugan, Shannon, Rozen, Steve, Gibbs, Richard A., Cho, Ting-Jan, Yan Ding, Wilson, Richard K., Jennifer F. Hughes, Helen Skaletsky, Steve Rozen, Wang, Qiaoyan, David C. Page, Shannon Dugan, Nazareth, Lynne V., Veizer, Joelle, Page, David C, Holland Kotkiewicz, Wesley C. Warren, Joelle Veizer, Holder, Michael, Donna M. Muzny, Colin Kremitzki, Brown, Laura G., Courtney, Laura, Fulton, Robert S., Richard K. Wilson, Buhay, Christian J., Robert S. Fulton, Ding, Yan, Andrew Cree, Pyntikova, Tatyana, Qiaoyan Wang, Hughes, Jennifer F., Michael Holder, Kremitzki, Colin, Skaletsky, Helen, Hua Shen, Ting-Jan Cho, Natalia Koutseva, Lynne V. Nazareth, Laura G. Brown, Laura Courtney, Koutseva, Natalia, Shen, Hua, Kotkiewicz, Holland, Tatyana Pyntikova   +53 more
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Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.

, 2020
Variants in genes encoding synaptic adhesion proteins of the neuroligin family, most notably neuroligin-4, are a significant cause of autism spectrum disorders in humans.
Maxeine, S., Südhof, T., Südhof, Thomas C., Südhof, Thomas C, Benseler, Fritz, Benseler, F., Brose, Nils, Nowick, Katja, Krasteva-Christ, G., Brose, N., Maxeiner, Stephan, Krasteva-Christ, Gabriela   +11 more
core   +1 more source

Patterns of selective constraints in noncoding DNA of rice [PDF]

, 2007
Background Several studies have investigated the relationships between selective constraints in introns and their length, GC content and location within genes. To date, however, no such investigation has been done in plants.
Peter D Keightley, Fan Longjiang, Wang, Y, Wang Yu, Guo, X, Fan, L, Longjiang Fan, Keightley Peter D, Keightley, Peter, Yu Wang, Guo Xingyi, Xingyi Guo   +11 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source