Results 281 to 290 of about 1,551,359 (398)

The pomegranate (Punica granatum L. cv. 'Wonderful') genome and P. protopunica shed light on pomegranate domestication. Is Daru a wild stock? [PDF]

BMC Genomics
Slonimsky A, Lovky O, Harel-Beja R, Bar-Ya'akov I, Eshed R, Sherman A, Holland D, Ophir R.   +7 more
europepmc   +1 more source

SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks

Advanced Science, EarlyView.
SCRIPT is a novel method inferring single‐cell cis‐regulatory relationships (CRRs) from transcriptomic and chromatin accessibility data. SCRIPT incorporates two key innovations: graph causal attention networks supported by empirical CRR evidence, and representation learning enhanced through pretraining on atlas‐scale single‐cell data.
Yu Zhang, Baole Wen, Yifeng Jiao, Yuchen Liu, Xin Guo, Yushuai Wu, Jiyang Li, Limei Han, Yinghui Xu, Xin Gao, Yuan Qi, Yuan Cheng, Ying He, Weidong Tian   +13 more
wiley   +1 more source

Polyommatine Blue Butterflies Reveal Unexpected Integrity of the W Sex Chromosome Amid Extensive Chromosomal Fragmentation Linked to Telomere Restoration. [PDF]

Genome Biol Evol
Hospodářská M, Koutecký P, Koutková S, Vila R, Talavera G, Rindoš M, Provazníková I, Dalíková M, Nguyen P.   +8 more
europepmc   +1 more source

THE MEIOTIC CHROMOSOMES OF THE MALE LLAVEIELLA TAENECHINA MORRISON (COCCIDAE) AND THE QUESTION OF THE TERTIARY SPLIT

, 1940
Sally Hughes‐Schrader
openalex   +2 more sources

Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis

Chromosome Research, 2012
Daniël P. Melters, L. Paliulis, I. Korf, S. Chan   +3 more
semanticscholar   +1 more source

The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset

Advanced Science, EarlyView.
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng, Hua Wang, Li Zhang, Shiping Li, Yuan Yuan, Mengting Tian, Yi Qu, Junjie Ying, Meicen Zhou, Yong Hu, Jinglan Huang, Rong Zou, Fengyan Zhao, Xiaojuan Su, Qian Liu, Yan He, Jinxing Feng, Weimin Huang, Ying Luo, Zhemin Zhou, Wei Shen, Dezhi Mu, Shaopu Wang   +22 more
wiley   +1 more source

Heterogeneity in telomere length of human chromosomes.

Human Molecular Genetics, 1996
P. Lansdorp, N. Verwoerd, F. M. Rijke, V. Dragowska, M. Little, R. Dirks, A. Raap, H. Tanke   +7 more
semanticscholar   +1 more source

Tead1a Initiates Transcriptional Priming Through the TEAD1a/YAP‐Notch1‐Spi1/Cebpα Axis to Promote Neutrophil Fate

Advanced Science, EarlyView.
This study discovered that the protein TEAD1a is crucial for neutrophil development. In zebrafish models, disrupting TEAD1a or its interaction with partner protein YAP1 caused severe neutrophil deficiency. TEAD1a functions during the early HSC stage, activates Notch1 signaling in the GMP stage, and triggers Spi1 and Cebpα to drive neutrophil terminal ...
Wang Yiqin, Yang Ruimeng, Wang Peihong, Liu Xiaohui, Yuan Hao, Huang Hongli, Zhou Yongjian, Xie Baoshu   +7 more
wiley   +1 more source

Influence of Gonadal and Chromosomal Sex on the Brain Transcriptome in a Mouse Species with Natural Sex Reversal. [PDF]

Mol Biol Evol
Heitzmann LD, Saunders PA, Perez J, Boursot P, Veyrunes F.   +4 more
europepmc   +1 more source

Pathogenicity of Mediator Complex Subunit 27 (MED27) in a Neurodevelopmental Disorder with Cerebellar Atrophy

Advanced Science, EarlyView.
MED27 is one of the 26 subunits in the human Mediator complex (MED). Neurodevelopmental disorder‐causing MED27 genetic variants induce instability of MED, leading to disrupted DNA occupancy, altered chromatin interaction, and subsequent transcriptional dysregulation of critical downstream genes, including master regulatory transcription factors ...
Nuermila Yiliyaer, Xiaocheng Li, Tianyu Guo, Haiying Zhou, Lihai Gong, Luowei Yuan, Yang Fu, Yulong Qiao, Ying Lam Lui, Nuo Chen, Pengfei Lin, Hoi Hung Cheung, Ho Ko, Linyan Meng, Xiao Chen, Yong Lei, Kin Ming Kwan, Huating Wang, Shen Gu   +18 more
wiley   +1 more source