Results 111 to 120 of about 2,897,650 (254)

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Electroclinical phenotypes—genetic characterization of developmental and epileptic encephalopathies in a cohort study

Epileptic Disorders, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by refractory seizures and frequently recurring epileptic activity with neurodevelopmental delay or regression that usually begin in early life. We aimed to define the relationship between electroclinical features and etiology, as well as the genotype–phenotype ...
Burcu Yaman, Fulya Kurekci, Sinan Akbas, Ceyda Oney, Mehmet Akif Kilic, Hulya Maras Genc, Ayca Dilruba Aslanger, Edibe Pembegul Yildiz   +7 more
wiley   +1 more source

Possibilities of target therapy of chronic cerebral ischemia

Лечащий Врач, 2021
Approaches to treatment of patients with chronic form of cerebrovascular diseases were presented. Nootropic, vascular and antioxidant effects of complex therapy were demonstrated, which allow to significantly reduce such wide-spread complaints as headaches, giddiness, asthenia and vegetative disorders.
openaire   +1 more source

Influence of Cilostazol on Changes in Cyclin D1 Expression in Cerebral Cortex of Rats with Chronic Cerebral Ischemia. [PDF]

Physiol Res, 2020
Wei AX, Shao MY, Liu Y, Sun Y, Wang LM, Ma XY, Mang J, Xu ZX.   +7 more
europepmc   +1 more source

Does age influence diagnostic outcomes in an adult cohort referred to a first‐seizure clinic?

Epilepsia, EarlyView.
Abstract Objective The aging Danish population is associated with increasing morbidity and healthcare utilization. This study examines age‐related differences in resource utilization and diagnostic outcomes between older (65–95 years) and younger adults (18–64 years) evaluated for suspected epilepsy, including clinical management, diagnostic yield, and
Anne Line Lund Birkmose, Corinna Lackmann, Lars Hageman Pinborg, Kimmo Jensen   +3 more
wiley   +1 more source

Intranasal injection of recombinant human erythropoietin improves cognitive and visual impairments in chronic cerebral ischemia rats. [PDF]

Biomed Rep, 2020
Zhou Y, Sun B, Guo J, Zhou G.
europepmc   +1 more source

Prediction of subsequent seizures after acute symptomatic seizures in critically ill children: A clinical–electroencephalographic model

Epilepsia, EarlyView.
Abstract Objective We aimed to determine the risk of subsequent seizure or epilepsy diagnosis after acute symptomatic seizures (ASyS) in critically ill children, evaluate whether antiseizure medication (ASM) use is associated with subsequent seizure/epilepsy diagnosis, and develop a simple Seizure/Epilepsy Risk Score to predict subsequent seizure ...
Nicholas S. Abend, France W. Fung, Darshana S. Parikh, Mark Ramos, Rui Xiao, Alexis A. Topjian   +5 more
wiley   +1 more source

Non‐contrast MRI reliably captures perfusion abnormalities in status epilepticus

Epilepsia, EarlyView.
Abstract Objective To determine whether non‐contrast pseudo‐continuous arterial spin labeling (pCASL) detects status epilepticus (SE)–related perfusion abnormalities and shows quantitative correspondence with dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI), and to compare single‐slice and volumetric approaches for ...
Lukas Machegger, Pilar Bosque‐Varela, Jürgen Steinbacher, Johannes Pfaff, Eugen Trinka, Giorgi Kuchukhidze   +5 more
wiley   +1 more source

Prognosis of acute symptomatic seizures and impact of prolonged treatment with anti‐seizure medication

Epilepsia, EarlyView.
Abstract Objectives Acute symptomatic epileptic seizures (ASySs) occur in temporal proximity to acute brain insults. Given their low risk of subsequent unprovoked seizures, current guidelines recommend either no treatment with anti‐seizure medication (ASM) or early discontinuation, yet ASM treatment is often continued beyond hospital discharge.
Hannah Traben, Julia Herzig‐Nichtweiß, Lisa Langenbruch, Felix Kohle, Johann O. Pelz, Piergiorgio Lochner, Matthias Wittstock, Albrecht Günther, Angelika Alonso, Marko Blickhan, Silvia Schönenberger, Sascha Berning, Michael P. Malter, Annekatrin Müller, Frauke Röll, Waldemar Gubarev, Kai M. Schubert, Marian Galovic, Maximilian Mönch, Ulrike Grittner, Martin Holtkamp, Farid Salih, Bernd J. Vorderwülbecke, for the IGNITE! Study Group   +23 more
wiley   +1 more source

Late electroencephalographic seizure‐risk findings and restricted diffusion on magnetic resonance imaging as seizure‐burden markers associated with neurological deficits after status epilepticus in a remote or chronic cohort

Epilepsia, EarlyView.
Abstract Objective To evaluate whether time‐dependent electroencephalographic (EEG) seizure risk findings and restricted diffusion on magnetic resonance imaging (MRI) are associated with neurological outcomes after status epilepticus (SE), beyond seizure duration. Methods This two‐center observational study included consecutive SE patients from 2017 to
Narumi Ohno, Shuichiro Neshige, Riho Okada, Takafumi Abe, Keito Ishihara, Megumi Nonaka, Haruka Ishibashi, Megumi Toko, Takeo Shishido, Dai Agari, Yu Yamazaki, Koji Iida, Hirofumi Maruyama   +12 more
wiley   +1 more source