Results 91 to 100 of about 2,897,650 (254)

The Influence of Apolipoprotein E Deficiency on Collateral Vessel Growth in Experimental Chronic Cerebral Ischemia in Mice

THE INFLUENCE OF APOLIPOPROTEIN E DEFICIENCY ON COLLATERAL VESSEL GROWTH IN EXPERIMENTAL CHRONIC CEREBRAL ISCHEMIA IN MICE The Influence of Apolipoprotein E Deficiency on Collateral Vessel Growth in Experimental Chronic Cerebral Ischemia in Mice ...
Mielke, Anna-Maria
core  

Glutamatergic and central cholinergic dysfunction in the CA1, CA2 and CA3 fields on spatial learning and memory in chronic cerebral ischemia—Induced vascular dementia of rats

, 2016
Chronic cerebral ischemia (CCI) is associated with cognitive decline in aging, vascular dementia and Alzheimer’s disease. Substantial evidence has shown that chronic cerebral ischemia may cause cognitive impairment, but the underlying neurobiological ...
Lin, Ping, Du, Yifenf, Du, Yifeng, Yan, Yongxing, Fan, Yongjun, Liang, Lizhen, Jin, Mudan, Gou, Zengmei, Cao, Yanjing   +8 more
core   +1 more source

Translational Macrophage Mechano‐Immunotherapy for Next‐Generation Implantable Biomaterials

Advanced NanoBiomed Research, EarlyView.
This review explores how macrophage mechanosensing drives inflammation, fibrosis and foreign body responses to implanted biomaterials. It examines emerging pharmacological strategies to modulate mechanotransduction, alongside biomaterial platforms for localised drug delivery, clinical translation, regulatory considerations and standardised testing ...
Xueying Xu, Ian L. Chin, Richard P. Tan
wiley   +1 more source

Aberrant oligodendroglial LDL receptor orchestrates demyelination in chronic cerebral ischemia. [PDF]

J Clin Invest, 2021
Xie Y, Zhang X, Xu P, Zhao N, Zhao Y, Li Y, Hong Y, Peng M, Yuan K, Wan T, Sun R, Chen D, Xu L, Chen J, Guo H, Shan W, Li J, Li R, Xiong Y, Liu D, Wang Y, Liu G, Ye R, Liu X.   +23 more
europepmc   +1 more source

Cognitive reserve of patients with chronic cerebral ischemia

Bulletin of Russian State Medical University
Cognitive reserve (CR) is characterized by the ability to engage neural networks for adaptive reorganization of brain functions in response to damage or stress. This study aimed to identify the structural and functional organization of neural networks in patients with chronic cerebral ischemia (CCI) having different CR.
VF Fokin, NV Ponomareva, AA Shabalina, RN Konovalov, RB Medvedev, AI Boravova, OV Lagoda, MV Krotenkova, MM Tanashyan   +8 more
openaire   +1 more source

Population pharmacokinetics of levetiracetam in term neonates with hypoxic–ischemic encephalopathy and therapeutic hypothermia: The LEVNEONAT‐1 study

British Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to describe the pharmacokinetics (PK) of levetiracetam (LEV) in term neonates treated for neonatal seizures secondary to hypoxic–ischemic encephalopathy (HIE). Methods Fifteen neonates were included and received a loading dose ranging from 30 to 60 mg/kg followed by eight maintenance doses corresponding to one‐fourth of the loading
Léo Mimram, Moreno Ursino, Julie Leger, Emilie Bourrel‐Ponchel, Florence Flamein, Alexandra Chadie, Isabelle Guellec, Sarah Zohar, Vincent Jullien, Géraldine Favrais   +9 more
wiley   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Study of Neuroprotection by a Combination of the Biological Antioxidant (Eucalyptus Extract) and the Antihypertensive Drug Candesartan against Chronic Cerebral Ischemia in Rats. [PDF]

Molecules, 2021
Trabolsi C, Takash Chamoun W, Hijazi A, Nicoletti C, Maresca M, Nasser M.   +5 more
europepmc   +1 more source

Viscosity Effects on Blood Flow Dynamics: Influence of Isovolemic Hemodilution on Focal Cerebral Ischemia

In recent years there has been considerable clinical interest in the efficacy of both hypervolemic hemodilution [6, 7, 20] and isovolemic hemodilution [9, 26] in the prevention or treatment of cerebral ischemia.
Karacostas, D., Hyodo, A., Zervas, N. T., Tu, Y.-K., Candia, G., Heros, R. C., LeGree, K.   +6 more
core   +1 more source

Diabetic chronic hyperglycemia and cerebral pH recovery following global ischemia in dogs.

, 1994
We determined the effect of chronic hyperglycemia associated with diabetes on recovery of cerebral pH after global incomplete cerebral ischemia. 31P magnetic resonance spectra and cerebral blood flow (radiolabeled microspheres) were measured in
F E Sieber, P R Brown, S M Eleff, R C Koehler, R J Traystman   +4 more
core   +1 more source