Results 21 to 30 of about 7,344,469 (193)

Immunopharmacological approach of carvedilol in chronic Chagas heart disease. [PDF]

Arq Bras Cardiol, 2014
Dear Editor, Evidence suggests that approximately 12 million individuals in Latin America are infected with Trypanosoma cruzi and present Chagas disease1. Even though the disease was described more than 100 years ago, chemotherapy directed against its etiological agent is restricted to two compounds which are only effective in the acute phase of the
Miranda CP, Botoni FA, Rocha MO.
europepmc   +5 more sources

Endomyocardial biopsy in Chagas' heart disease: pathogenetic contributions

São Paulo Medical Journal
Endomyocardial biopsy procedure has been performed in many centers around the world, allowing a better treatment and follow up of the patients with myocardial disease.
Maria de Lourdes Higuchi
doaj   +2 more sources

Pathogenesis of Chronic Chagas Heart Disease [PDF]

Circulation, 2007
Background— Chagas disease remains a significant public health issue and a major cause of morbidity and mortality in Latin America. Despite nearly 1 century of research, the pathogenesis of chronic Chagas cardiomyopathy is incompletely understood, the most intriguing challenge of which is the complex
Jose Antonio, Marin-Neto, Edécio, Cunha-Neto, Benedito C, Maciel, Marcus V, Simões   +3 more
openaire   +2 more sources

Different infective forms trigger distinct immune response in experimental Chagas disease. [PDF]

, 2012
Although metacyclic and blood trypomastigotes are completely functional in relation to parasite-host interaction and/or target cell invasion, they differ in the molecules present on the surface.
Olindo Assis Martins-Filho, Carneiro Cláudia Martins, Martins-Filho, Olindo Assis, Alexandre Barbosa Reis, Cláudia Martins Carneiro, Francisco Amanda Fortes, Washington Luiz Tafuri, Carvalho, Andrea Teixeira, Machado Evandro Marques de Meneses, Nogueira, Nívia Carolina, Franscisco, Amanda Fortes, Evandro Marques de Meneses Machado, Vieira, Paula Melo de Abreu, Fonseca, Kátia da Silva, Francisco, Amanda Fortes, Andrea Teixeira-Carvalho, Paula Melo de Abreu Vieira, Nogueira, N??via Carolina, Machado, Evandro Marques de Menezes, Vieira Paula Melo de Abreu, Machado, Evandro Marques de Meneses, Tafuri, Washington Luiz, Reis Alexandre Barbosa, Teixeira-Carvalho Andrea, Reis, Alexandre Barbosa, Martins-Filho Olindo Assis, Nívia Carolina Nogueira, Kátia da Silva Fonseca, Carvalho, Andréa Teixeira de, Nogueira Nívia Carolina, Amanda Fortes Francisco, Tafuri Washington Luiz, Teixeira-Carvalho, Andrea, Carneiro, Cláudia Martins, Martins Filho, Olindo Assis, Fonseca Kátia da Silva   +35 more
core   +2 more sources

Epicardial ablation for ventricular tachycardia in chronic Chagas heart disease. [PDF]

Arq Bras Cardiol, 2014
The Chagas Heart Disease, described for the first time in 1909 by Carlos Chagas, is caused by Trypanosoma cruzi, a flagellated protozoa transmitted to humans, mostly by the feces of Triatoma infestans in endemic areas. Estimates are that fifteen million people are infected in Latin America, leading to 45,000 deaths per year, 90% owing to heart disease.
Scanavacca M.
europepmc   +5 more sources

Chagas Disease and Heart Failure: An Expanding Issue Worldwide [PDF]

, 2019
Chagas disease, originally a South American endemic health problem, is expanding worldwide because of people migration. Its main impact is on the cardiovascular system, producing myocardial damage that frequently results in heart failure.
Eduardo Perna, Sergio V Perrone, Felipe Martinez, Alvaro Sosa Liprandi   +3 more
core   +1 more source

Mitochondrial DNA Haplogroups and Variants Predispose to Chagas Disease Cardiomyopathy

Hearts, 2023
Cardiomyopathies are major causes of heart failure. Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central and South America.
Frédéric Gallardo, Pauline Brochet, David Goudenège, João Paulo Silva Nunes, Pauline Andrieux, Barbara Maria Ianni, Amanda Farage Frade, Charles Mady, Ronaldo Honorato Barros Santos, Andreia Kuramoto, Samuel Steffen, Antonio Noedir Stolf, Pablo Pomerantzeff, Alfredo Inacio Fiorelli, Edimar Alcides Bocchi, Cristina Wide Pissetti, Bruno Saba, Fabrício C. Dias, Marcelo Ferraz Sampaio, Fabio Antônio Gaiotto, José Antonio Marin-Neto, Abílio Fragata, Ricardo Costa Fernandes Zaniratto, Sergio Siqueira, Giselle De Lima Peixoto, Fernando Bacal, Paula Buck, Rafael Ribeiro Almeida, Hui Tzu Lin-Wang, André Schmidt, Mario Hiroyuki Hirata, Eduardo Antonio Donadi, Alexandre Costa Pereira, Virmondes Rodrigues Junior, Martino Martinelli, Michel Naslavsky, Jorge Kalil, Vincent Procaccio, Edecio Cunha-Neto, Christophe Chevillard   +39 more
doaj   +1 more source

4.1 PILOT STUDY ON THE PRECLINICAL VASCULAR DAMAGE IN BOLIVIAN PATIENTS WITH CHAGAS INDETERMINATE CHRONIC PHASE

Artery Research, 2017
Background: In Italy, the prevalence of seropositivity for Trypanosoma cruzi in immigrants from endemic countries is about 11.3% (30.7% for Bolivian immigrants).
Filippo Valbusa, Andrea Angheben, Verena Zerbato, Andrea Chiampan, Davide Agnoletti, Cristiano Fava, Zeno Bisoffi, Guido Arcaro   +7 more
doaj   +1 more source

Enhancing patient care: a multimodality strategy for dilated cardiomyopathy in Chagas disease [PDF]

Exploration of Cardiology
Chagas disease is a systemic illness characterized by acute and chronic phases. If untreated, it can lead to dysfunction of vital organs, notably the heart, ultimately resulting in heart failure.
Luigy Vasquez-Yeng, Juan Jose Hernandez-Ruiz, Mauricio Garcia-Cardenas, Raul Velazquez-Castañeda, Santiago Luna-Alcala, Pavel Martinez-Dominguez, Enrique C. Guerra, José Armendariz-Ferrari, Nilda Espinola-Zavaleta   +8 more
doaj   +1 more source

Increased aortic stiffness in adults with chronic indeterminate Chagas disease.

PLoS ONE, 2019
An ever-increasing number of patients with chronic indeterminate Chagas disease are diagnosed with early vascular and cardiac abnormalities, as cardiovascular imaging becomes more sensitive.
Filippo Valbusa, Andrea Angheben, Alessandro Mantovani, Verena Zerbato, Andrea Chiampan, Stefano Bonapace, Paola Rodari, Davide Agnoletti, Guido Arcaro, Cristiano Fava, Zeno Bisoffi, Giovanni Targher   +11 more
doaj   +1 more source