Results 71 to 80 of about 84,272 (327)

Ultrasonographic follow-up of functional chronic constipation in adults: A report of two cases

SAGE Open Medical Case Reports, 2017
Chronic constipation is a disorder frequently encountered in clinical practice. Here, we describe the use of ultrasonography as a new approach to the follow-up of adult patients with functional chronic constipation.
Koichi Yabunaka, Gojiro Nakagami, Kazunori Komagata, Hiromi Sanada   +3 more
doaj   +1 more source

Multimorbidity in bipolar disorder and under-treatment of cardiovascular disease: a cross sectional study [PDF]

, 2013
Background: Individuals with serious mental disorders experience poor physical health, especially increased rates of cardiometabolic morbidity and premature morbidity.
A Weeke, AJ Ferrari, AJ Mitchell, B Felker, B Ya-Mei, Bruce Guthrie, C Astrup, C Crump, CW Colton, Daniel J Smith, Daniel Martin, DJ Smith, E Koranyi, EH Høyer, F Angst, FG Joseph, Gary McLean, J Johnson, J Langan, JA Mackell, Julie Langan, K Barnett, LM Koran, M De Hert, M De Hert, M De Hert, M Tohen, MJ Fleury, MT Tsuang, N Myles, O Bratfos, P Vestergaard, PA Kurdyak, R Sharma, RM Weinryb, SH Han, Stewart W Mercer, T Callréus, TM Laursen, TM Laursen, U Osby, U Petterson, VMR Carstairs   +42 more
core   +2 more sources

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

Defining constipation to estimate its prevalence in the community: results from a national survey

BMC Gastroenterology, 2019
Background Different definitions of constipation have been used to estimate its prevalence in the community but this creates difficulties when comparing results from various studies.
Barry L. Werth, Kylie A. Williams, Murray J. Fisher, Lisa G. Pont   +3 more
doaj   +1 more source

Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe, Jessica Connors, Angela Arra, Katherine Dunn, Kim Blake, Johan van Limbergen   +5 more
wiley   +1 more source

Chronic Constipation: Current Management and Challenges

Canadian Journal of Gastroenterology, 2011
Many challenges are associated with the diagnosis and management of patients with chronic constipation. Some of these challenges arise from the currently incomplete understanding of what causes constipation and from the difficulties in diagnosing and ...
Martin Storr
doaj   +1 more source

The Efficacy of Peripheral Opioid Antagonists in Opioid-Induced Constipation and Postoperative Ileus: A Systematic Review of the Literature. [PDF]

, 2017
Opioid-induced constipation has a negative impact on quality of life for patients with chronic pain and can affect more than a third of patients. A related but separate entity is postoperative ileus, which is an abnormal pattern of gastrointestinal ...
Baratta, Jaime L., Grant, Alexander E., McNulty, Stephen E., Schwenk, Eric S., Torjman, Marc C., Viscusi, Eugene R.   +5 more
core   +1 more source

Intestinal microbiota and chronic constipation [PDF]

SpringerPlus, 2016
Chronic constipation is a prevalent, burdensome gastrointestinal disorder whose aetiology and pathophysiology remains poorly understood and is most likely multifactorial. Differences in the composition of the intestinal microbiota have been demonstrated when constipated patients and healthy controls have been compared.
Ying Zhao, Yan-Bo Yu
openaire   +3 more sources

Children With 22.Q.11.2 Deletion Syndrome: Sleep‐Disordered Breathing and Management

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Patients with 22q11.2 deletion syndrome (22q11DS) are predisposed to obstructive sleep apnea (OSA) due to an abnormal craniofacial anatomy with pharyngeal hypotonia, retrognathia, micrognathia, and glossoptosis. The aim of the study was to describe the prevalence and management of OSA in a cohort of children with 22q11DS.
Domenico Paolo La Regina, Sonia Khirani, Lucie Griffon, Clément Poirault, Raffaella Nenna, Fabio Midulla, Brigitte Fauroux   +6 more
wiley   +1 more source

PolyMorphine provides extended analgesic-like effects in mice with spared nerve injury. [PDF]

, 2017
Morphine is a well-characterized and effective analgesic commonly used to provide pain relief to patients suffering from both acute and chronic pain conditions.
Chen, Renxun, Kolber, Benedict, Lax, Neil C, Leep, Sarah R, Uhrich, Kathryn, Yu, Lei   +5 more
core   +1 more source