Results 121 to 130 of about 325,222 (293)

Systematic literature review of treatments used for refractory or unexplained chronic cough in adults

Annals of Thoracic Medicine
BACKGROUND: Refractory or unexplained chronic cough (RCC or UCC) is difficult to manage and is usually treated by the off-label use of drugs approved for other indications.
Vishal Bali, Peter Kardos, Clive Page, Paola Rogliani, Luigino Calzetta, Ada Adriano, Aidan Byrne, Adekemi Adeyemi, Andrew Frederickson, Jonathan Schelfhout   +9 more
doaj   +1 more source

Efficacy of Gefapixant, a P2X3 Antagonist, for Refractory Atopic Cough

International Medical Case Reports Journal, 2023
Yoshihisa Ishiura, Shosaku Nomura, Yuka Ishii, Kai Imai, Yusuke Sawai, Takeshi Tamaki, Toshiki Shimizu, Naoyuki Miyashita, Tomoki Ito First Department of Internal Medicine, Kansai Medical University, Osaka, JapanCorrespondence: Yoshihisa Ishiura, First ...
Ishiura Y, Nomura S, Ishii Y, Imai K, Sawai Y, Tamaki T, Shimizu T, Miyashita N, Ito T   +8 more
doaj  

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan, Deng Liu, Wuhen Xu, Yang Li, Juanli Hu, Oppermann Henry, Alexander Fuchs, Rami Abou Jamra, Zhen Liu, Mei He, Yuanlu Chen, Shengnan Wu, Xiaohuan Dong, Yiqiao Chen, Pengchao Wang, Weiyue Gu, Han Jing, Yabing Tang, Ya‐Jie Wang, Xiao Mao, Neng Xiao   +20 more
wiley   +1 more source

The prevalence of Streptococcus equi subsp. equi carriers in the Netherlands

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies equi (S. equi) carriers are thought to be important drivers for strangles outbreaks. Limited data are available on the prevalence of carriers in European horse husbandry settings. Objectives To estimate the prevalence of S.
R. M. A. C. Houben, E. M. Broens, M. J. Broekhuizen‐Stins, M. M. Sloet van Oldruitenborgh‐Oosterbaan, C. van Maanen, J. A. P. Heesterbeek   +5 more
wiley   +1 more source

A Student‐Led Tele‐Expiratory Muscle Strength Training (EMST) Program for Head and Neck Cancer (HNC) Survivors—A Pilot Implementation Study

Head &Neck, EarlyView.
ABSTRACT Background Expiratory muscle strength training (EMST) is a non‐invasive, evidence‐based treatment that is used to improve swallowing in head and neck cancer (HNC) survivors. This prospective, pilot implementation study evaluated the feasibility, acceptability, and potential clinical effectiveness of a novel student‐led tele‐EMST program for ...
Katrina Blyth, Jessica Tam, Rachelle Robinson, Danielle Stone, Emma S. Wallace   +4 more
wiley   +1 more source

Automatic electrical stimulation of abdominal wall muscles increases tidal volume and cough peak flow in tetraplegia [PDF]

, 2008
<p>Paralysis of the respiratory muscles in people with tetraplegia affects their ability to breathe and contributes to respiratory complications.
Allan, D.B., Fraser, M.H., Gollee, H., Hunt, K.J., McLean, A.N.   +4 more
core  

Intensive Swallowing Rehabilitation for Head and Neck Cancer Survivors With Chronic Dysphagia: Outcomes From a Prospective Multicentre Cohort Study With 6‐Month Follow‐Up

Head &Neck, EarlyView.
ABSTRACT Background Chronic dysphagia persists in some head and neck cancer (HNC) survivors despite preventive exercises, negatively impacting quality of life. Evidence for effective rehabilitation strategies remains limited. Methods This prospective cohort study included 34 HNC survivors (≥ 1 year post‐treatment) who completed a 3‐week intensive ...
J. I. Oldenbeuving, L. van der Molen, J. T. Groothuis, J. G. Kalf   +3 more
wiley   +1 more source

Exploring the concept of disease control in chronic cough

ERJ Open Research
Background Disease control in chronic diseases is an overarching concept that reflects the degree to which the goals of therapy are met. However, to date, there is no consensus on the definition of disease control in chronic cough.
Jin Young Park, Haesung Jun, Seung-Eun Lee, Ha-Kyeong Won, Sung-Yoon Kang, Noeul Kang, Ji-Yoon Oh, Young-Chan Kim, So-Young Park, Jin An, Youngsang Yoo, Mi-Yeong Kim, Hwa Young Lee, Ji-Su Shim, Min-Hye Kim, Sae-Hoon Kim, Sang-Heon Kim, Yoon-Seok Chang, Sang-Hoon Kim, Byung-Jae Lee, Surinder S. Birring, Woo-Jung Song   +21 more
doaj   +1 more source

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

Head &Neck, EarlyView.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su, Matheus Sewastjanow‐Silva, Jack Phan, Marc‐Elie Nader, Shaan M. Raza, Franco DeMonte, Paul W. Gidley, Ehab Y. Hanna, Loretta A. Williams   +8 more
wiley   +1 more source