Results 141 to 150 of about 1,695,181 (246)
Strategic Change, EarlyView.ABSTRACT Deep‐technology ventures, particularly in medical artificial intelligence (AI), face a persistent “valley of death” where promising innovations fail to find viable business models despite technical merit. While the NSF I‐Corps program addresses this through structured customer discovery, little empirical research validates how specific market ...
Amil Khanzada, Takuji Takemoto
wiley +1 more source
Annals of Thoracic Medicine, 2007 The reported studies suggest a role for eosinophils in the pathogenesis of cough variant asthma. In the present study, the expired breath condensate level of hydrogen peroxide and pH were determined in patients with cough variant asthma and compared to ...
Ahmad Al Obaidi Amina
doaj
Journal of Surgical Oncology, EarlyView.ABSTRACT Robotic surgery has transformed head and neck cancer (HNC) treatment. This scoping review synthesizes evidence on transoral robotic surgery (TORS), focusing on applications, limitations, and future directions. Following PRISMA‐ScR guidelines, this review used the PCC framework (Population: HNC patients; Concept: technological advancements ...
Anna Luíza Damaceno Araújo +6 more
wiley +1 more source
Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough
The Laryngoscope, EarlyView.The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen +3 more
wiley +1 more source
Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes
The Laryngoscope, EarlyView.A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar +6 more
wiley +1 more source
Radiofrequency Neurolysis of the Posterior Nasal Nerve: A Systematic Review and Meta‐Analysis
The Laryngoscope, EarlyView.Radiofrequency neurolysis of the posterior nasal nerve significantly improves symptoms of chronic rhinitis, including nasal obstruction and rhinorrhea, while demonstrating a favorable safety profile. This systematic review and meta‐analysis supports the procedure as an effective minimally invasive treatment, although additional high‐quality randomized ...
Eyad Jamileh +5 more
wiley +1 more source
A Scoping Review of Laryngeal Edema Rating Scales for Extubated Acute Respiratory Failure Survivors
The Laryngoscope, EarlyView.This scoping review identified existing laryngeal edema rating scales and evaluated whether any are adequately designed for post‐extubation acute respiratory failure (ARF) survivors. Across 35 included studies, most used subjective binary classifications and only the RTOG and Patterson Edema scales had operational definitions and reliability/validity ...
Lalita Sabat +4 more
wiley +1 more source
Association of Glucagon‐Like Peptide—1 Receptor Analogues and Laryngeal Symptoms in Obese Adults
The Laryngoscope, EarlyView.Table 1 succinctly quantifies the time‑dependent association between GLP‑1RA/GIP therapy and laryngeal symptoms, demonstrating modest but statistically robust increases in outcomes such as cough and voice/resonance disorders by 6 months. It provides clinically actionable absolute risks, odds ratios, and hazard ratios that can directly inform counseling,
Priyanka Shah +4 more
wiley +1 more source
Patient-reported assessments of chronic cough in clinical trials: accessory or primary endpoints?
Chronic cough is a complex disorder that affects up to 5-10% of the general population. It can be challenging to manage as there are few effective treatments, although several novel antitussives are in clinical development.
Mackay, EC +3 more
core +1 more source