Results 151 to 160 of about 325,222 (293)
JPGN Reports, EarlyView.Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi +6 more
wiley +1 more source
Case series: Joubert syndrome and eosinophilic esophagitis
JPGN Reports, EarlyView.Abstract Joubert syndrome (JS) is a rare genetic disorder characterized by developmental abnormalities, particularly in the brainstem and cerebellar vermis, alongside multisystem manifestations such as kidney and liver anomalies, polydactyly, cleft lip or palate, and tongue defects.
Jonathon Schening +5 more
wiley +1 more source
When protein losing enteropathy persists: A case series of viral and lymphatic‐associated etiologies
JPGN Reports, EarlyView.Abstract Protein‐losing enteropathy (PLE) is a rare condition that is characterized by loss of plasma protein in the intestines leading to hypoproteinemia with subsequent peripheral edema and possibly anasarca. The pathophysiology of PLE varies depending on the etiology and involves either intestinal mucosal injury or lymphatic system alterations ...
Natalie Jennings +7 more
wiley +1 more source
Potential value of using pH‐impedance monitoring to evaluate for rumination syndrome in children
JPGN Reports, EarlyView.Abstract Objectives pH‐impedance monitoring (pH‐MII) is often used to evaluate severity and type of gastroesophageal reflux disease (GERD). The Nakagawa rumination score, which is derived using data from pH‐MII, has been proposed as a metric to diagnose rumination syndrome in adults. However, this approach has not been validated in children. Esophageal
Donna Ann Cheung, Aamer Imdad
wiley +1 more source
Gut function among children treated for severe acute malnutrition: A cohort study in Uganda
JPGN Reports, EarlyView.Abstract Objectives Impaired gut function in children with severe acute malnutrition (SAM) is associated with morbidity. We aimed to assess changes in six biomarkers representing different domains of gut function among children with complicated SAM during nutritional rehabilitation, and to identify predictors of these changes.
Betty Lanyero +12 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.In adults with atopic dermatitis and chronic pruritus, the mental comorbidity of Somatic Symptom Disorder is associated with higher average and worst pruritus intensity, higher psychological distress and lower quality of life. Additionally, there were nonsignificant changes in cutaneous nerve fiber densities in skin biopsies.
Stefan M. Kahnert +13 more
wiley +1 more source
RFC1 Repeat Expansion in Chronic Cough: Findings From the Korean Chronic Cough Registry. [PDF]
Allergy Asthma Immunol ResPark KE +9 more
europepmc +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang +5 more
wiley +1 more source