Results 81 to 90 of about 1,908,468 (288)

The effects of Bifidobacterium on the gut microbiome of macaques with chronic diarrhea

四川大学学报. 自然科学版, 2022
Macaca mulatta, as the most important non-human primate model animal, is widely used in biomedical research, so there are a large number of captive populations in the country.
SONG Jia-Rong, SHANG Ke, LEI Guang-Lun, LIU Xu, YANG Sheng-Zhi, HU Gang, YUE Bi-Song, FAN Zhen-Xin   +7 more
doaj  

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Association between ideal cardiovascular health and bowel conditions among US adults

Frontiers in Nutrition
ObjectiveThe aim of this study is to explore the relationship between ideal cardiovascular health (CVH), as assessed using the Life’s Essential 8 (LE8), and bowel conditions.MethodsThis cross-sectional study selected 11,108 participants aged ≥20 years ...
Yiwen Wang, Zhigang Wang
doaj   +1 more source

Pathophysiology, Evaluation, and Management of Chronic Watery Diarrhea. [PDF]

, 2017
Chronic watery diarrhea poses a diagnostic and therapeutic challenge and is often a disabling condition for patients. Although acute diarrhea is likely to be caused by infection, the causes of chronic diarrhea (>4 weeks in duration) are more elusive ...
Camilleri, Michael, Sellin, Joseph, Barrett, Kim   +2 more
core   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Bile Acid Diarrhea: An Etiology of Chronic Diarrhea Easily Overlooked

Chronic diarrhea is a symptom frequently noted in patients with various diseases. In addition to organic conditions, such as inflammatory bowel and neoplastic diseases, functional diseases including irritable bowel syndrome are important etiological ...
ISHIHARA, Shunji, Kinoshita, Yoshikazu, OOUCHI, Sachiko, SANUKI, Tsuyoshi, KAWASHIMA, Kosaku   +4 more
core   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

Advanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti, Valerio Di Lisio, Lucia Cardo, Alessandro Camilli, Estela Moretón Alfonsín, Daniele Cangialosi, Amaia Iturrospe Ibarra, Arantxa Arbe, Maurizio Prato   +8 more
wiley   +1 more source

EVALUATING LACTOFERRIN AND CALPROTECTIN AS MARKERS OF INTESTINAL INFLAMMATION INCHRONIC PANCREATITIS [PDF]

Arquivos de Gastroenterologia
Background: The treatment of chronic pancreatitis does not consistently solve intestinal abnormalities, and despite the implementation of various therapeutic measures, patients often continue to experience persistent diarrhea. Therefore, it is imperative
Claudia Teresa CARVENTE, Maria Lúcia Cardoso Gomes FERRAZ, Carlos Fischer de TOLEDO   +2 more
doaj   +1 more source

The Protective Factors Against Childhood Diarrhea in Indonesia

, 2020
Diarrhea is one of the leading causes of children under five years old morbidity and mortality in Indonesia. Children characteristics, immune protection program, hygiene and sanitation, socio economic and geographic determinants were analysed by ...
Ketti, Fera
core