Results 201 to 210 of about 5,016,105 (350)

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

Reproductive Fitness and the Links to Chronic Disease and Systemic Aging. [PDF]

Physiology (Bethesda)
Ghazi A, Henry H.
europepmc   +1 more source

Transient elastography compared to liver biopsy and morphometry for predicting fibrosis in pediatric chronic liver disease: Does etiology matter?

, 2016
Behairy El-Sayed Behairy, Mostafa Mohamed Sıra, Khaled Zalata, El-Sayed Ebrahem Salama, Mohamed Abdallah   +4 more
openalex   +2 more sources

Positive Orientation as a Predictor of Health Behavior during Chronic Diseases [PDF]

, 2019
Ewa Kupcewicz, Anna Szypulska, Anna Doboszyńska   +2 more
openalex   +1 more source

THE CHALLENGE OF CHRONIC DISEASES

AJN, American Journal of Nursing, 1930
Joseph C. Doane, Ernest P. Boas, Nicholas Michelson   +2 more
openaire   +2 more sources

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

Chronic Kidney Disease and Intraocular Pressure

, 2009
Monisha E. Nongpiur, Tien Yin Wong, Charumathi Sabanayagam, Su-Chi Lim, E Shyong Tai, Tin Aung   +5 more
openalex   +2 more sources

Association of Left Ventricular Diastolic Dysfunction With Cardiovascular Outcomes in Patients With Pre-dialysis Chronic Kidney Disease: Findings From KNOW-CKD Study

, 2022
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Kook‐Hwan Oh, Kyu Hun Choi, Yun Kyu Oh, Seong Kwon, Soo Wan Kim   +9 more
openalex   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

A consensus statement on health-care transition of patients with childhood-onset chronic kidney diseases: providing adequate medical care in adolescence and young adulthood [PDF]

, 2018
Wataru Kubota, Masataka Honda, Hirokazu Okada, Motoshi Hattori, Masayuki Iwano, Yuko Akioka, Akira Ashida, Yukihiko Kawasaki, Hideyasu Kiyomoto, Mayumi Sako, Yoshio Terada, Daishi Hirano, Mikiya Fujieda, Shouichi Fujimoto, Takao Masaki, Shuichi Ito, Osamu Uemura, Yoshimitsu Gotoh, Yasuhiro Komatsu, Shinichi Nishi, Mitsue Maru, Ichiei Narita, Shoichi Maruyama   +22 more
openalex   +1 more source