Results 11 to 20 of about 616,613 (359)

Chronic hepatitis [PDF]

Postgraduate Medicine, 1974
Chronic hepatitis may be viral or "lupoid" or may be related to drug use, alcoholism, or Wilson's disease. This article outlines the routine and special laboratory investigations that are indicated when the presence of chronic hepatitis is suspected from symptoms referable to the liver or from biochemical or physical abnormalities in an asymptomatic ...
openaire   +5 more sources

Quality of life in patients with chronic hepatitis C [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2011
Introduction. Hepatitis C virus often causes chronic liver disease reducing physical, mental and social functions in these patients. Objective. The aim of this investigation was analysis of the quality of life in chronic hepatitis C patients compared ...
Pavić Slađana, Delić Dragan, Simonović Jasmina, Švirtlih Neda   +3 more
doaj   +1 more source

A deep learning model to predict RNA-Seq expression of tumours from whole slide images

Nature Communications, 2020
RNA-sequencing of tumour tissue can provide important diagnostic and prognostic information but this is costly and not routinely performed in all clinical settings. Here, the authors show that whole slide histology slides—part of routine care—can be used
Benoît Schmauch, Alberto Romagnoni, Elodie Pronier, Charlie Saillard, Pascale Maillé, Julien Calderaro, Aurélie Kamoun, Meriem Sefta, Sylvain Toldo, Mikhail Zaslavskiy, Thomas Clozel, Matahi Moarii, Pierre Courtiol, Gilles Wainrib   +13 more
doaj   +1 more source

ETIOLOGICAL CHARACTERISTICS OF CHRONIC VIRAL HEPATITIS IN THE KHOREZM REGION OF UZBEKISTAN

Байкальский медицинский журнал, 2023
A study of the etiological structure of chronic viral hepatitis is presented, taking into account the assessment of the stage of the pathological process and the genotypic affiliation of pathogens in the Khorezm region of the Republic of Uzbekistan.
Shavkat R. Yusupov, Kurban A. Aitov, Evgeny D. Savilov, Dilfuza K. Abdullayeva, Safar E. Umirov   +4 more
doaj   +1 more source

Incidence, prevalence, and clinical course of hepatitis C following liver transplantation [PDF]

, 1992
Hepatitis C virus (HCV) is the agent responsible for posttransfusion hepatitis. The incidence, timing, and clinical course of HCV positive hepatitis in liver transplant recipients are unknown.
A.Jake Demetris, Aach, Alter, Barcena, Barrera, Brillanti, Choo, Colombo, David H. Van Thiel, Esteban, Esteban, Feinman, Grandele, Gray, Gunjan Shah, Hernandez, Jessica H. Lewis, Judith S. Gavaler, Kaplan, Knodell, Kuo, Kühnl, Mattsson, McFarlane, McHutchison, Noel, Poel, Read, Read, Rumi, Saturo Todo, Simonetti, Stevens, Thomas E. Starzl, Trainer, Weiner   +35 more
core   +1 more source

Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-Naïve chronic HBV patients [PDF]

, 2013
Background: Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness.
Abedi, F., Alavian, S.M., Ataei, B., Azad, T.M., Daram, M., Fazeli, Z., Ghamari, S., Goodarzi, Z., Jazayeri, S.M., Judaki, M.A., Kalantari, E., Karimzadeh, H., Keyvani, H., Khedive, A., Mahabadi, M., Mahmoodi, M., Malekzadeh, R., Mansour-Ghanaei, F., Montazeri, G., Moradi, A., Nejatizadeh, A., Norouzi, M., Pourhosseingholi, M.A., Rafatpanah, H., Ramezani, F., Saberfar, E., Saberfiroozi, M., Samimirad, K., Sanei-Moghaddam, I., Sarizadeh, G., Sayad, B., Somi, M.H., Yaran, M., Ziee, M.   +33 more
core   +1 more source

Correlation between hepatitis B G1896A precore mutations and HBeAg in chronic HBV patients [PDF]

, 2015
Background: Hepatitis B virus (HBV) infection is an important health concern worldwide, with critical outcomes. Hepatitis B e antigen (HBeAg) negative chronic hepatitis B is frequently caused by a mutation (G1896A) in the hepatitis B virus (HBV) precore (
Adli, A.H., Karami, C., Khodabakhshi, B., Moradi, A., Tabarraei, A., Zhand, S.   +5 more
core   +1 more source

Chronic Hepatitis C [PDF]

Gut and Liver, 2011
The goal of antiviral therapy for patients with chronic hepatitis C virus (HCV) infection is to attain a sustained virologic response (SVR), which is defined as undetectable serum HCV-RNA levels at 6 months after the cessation of treatment. Major improvements in antiviral therapy for chronic hepatitis C have occurred in the past decade. The addition of
Jang, Jae Young, Chung, Raymond T.
openaire   +3 more sources

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

Nature Communications, 2016
Cyclophilins play a key role in the life cycle of many viruses and represent important drug targets for broad-spectrum antiviral therapies. Here, the authors use fragment-based drug discovery to develop non-peptidic inhibitors of human cyclophilins with ...
Abdelhakim Ahmed-Belkacem, Lionel Colliandre, Nazim Ahnou, Quentin Nevers, Muriel Gelin, Yannick Bessin, Rozenn Brillet, Olivier Cala, Dominique Douguet, William Bourguet, Isabelle Krimm, Jean-Michel Pawlotsky, Jean- François Guichou   +12 more
doaj   +1 more source

Lipoprotein Receptors and Lipid Enzymes in Hepatitis C Virus Entry and Early Steps of Infection

Scientifica, 2012
Viruses are obligate intracellular agents that depend on host cells for successful propagation, hijacking cellular machineries to their own profit. The molecular interplay between host factors and invading viruses is a continuous coevolutionary process ...
Eve-Isabelle Pécheur
doaj   +1 more source