Results 41 to 50 of about 262,635 (315)

Killer cell immunoglobulin-like receptor alleles influence susceptibility to occult hepatitis B infection in West African population

Journal of Public Health in Africa, 2023
Occult hepatitis B infection (OBI) is a public health problem in Burkina Faso. OBI represents a risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC).
Momeiyi M. Bazie, Florencia W. Djigma, Mahamoudou Sanou, Pegdwendé A. Sorgho, Abdoul K. Ouattara, Dorcas Obiri-Yeboah, Nadege Kapieko, Herman K. Sombie, Prosper Bado, Edwige T. Yelemkoure, Isabelle T. Kiendrebeogo, Marius B. Nagalo, Albert T. Yonli, Jacques Simpore   +13 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Treatment of Chronic Hepatitis B

Antiviral Therapy, 2007
Hepatitis B virus (HBV) infection is the leading cause of chronic liver disease and hepatocellular carcinoma worldwide. Approximately 350 million individuals are infected with HBV and >500,000 deaths per year can be attributed to HBV. Although universal vaccination has reduced HBV incidence in many countries, it still remains a major public health ...
Rohit Loomba, T. Jake Liang
openaire   +6 more sources

Functionalized Antifouling Polymer Brushes for Biospecific Surfaces

Advanced Materials Interfaces, EarlyView.
Modern biosensors offer high sensitivity but often struggle with long‐term stability and selectivity for specific targets. Antifouling polymer brushes help enhance both stability and selectivity. In this review, we compare recent antifouling coatings, their design parameters, and how they are integrated with biorecognition elements for improved ...
Erik J. Postma, Luc Scheres, Sissi de Beer, Andriy R. Kuzmyn, Han Zuilhof   +4 more
wiley   +1 more source

“To die is better than to tell”: reasons for and against disclosure of chronic hepatitis B status in Ghana

BMC Public Health, 2020
Background People with a condition subject to stigmatisation, such as chronic hepatitis B, face the dilemma of whether or not to disclose their status. In Ghana, 12.3% of the adult population has the hepatitis B virus (HBV). One key strategy for breaking
Charles Ampong Adjei, Sarah E. Stutterheim, Florence Naab, Robert A. C. Ruiter   +3 more
doaj   +1 more source

Polymer Nanogels with Albumin Reporting Interface Created Using RAFT Precipitation Polymerization for Disease Diagnosis and Food Testing

Advanced Materials Interfaces, EarlyView.
Herein, polymer nanogels with a reporting interface for albumin are synthesized through reversible addition–fragmentation chain transfer (RAFT) precipitation polymerization of di(ethylene glycol) methyl ether methacrylate and N,N’‐methylenebis(acrylamide) using a poly(2‐methacryloyloxyethyl phosphorylcholine) macro‐RAFT agent, followed by dansyl ...
Yukiya Kitayama, Erika Yoshimatsu, Atsushi Harada   +2 more
wiley   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source