Results 31 to 40 of about 1,856,298 (304)

TLRs and chronic inflammation [PDF]

The International Journal of Biochemistry & Cell Biology, 2010
After the discovery of Toll-like receptors (TLRs), innate immune mechanisms came back in the focus of scientific research. With more and more mechanisms of TLR biology known, it has become clear that these and also other innate immune receptors are not only of crucial importance in the immune response to invading pathogens, but also play a role in the ...
Ospelt, C, Gay, S
openaire   +3 more sources

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence, Keenan, Bridget P, Kelley, Robin K   +2 more
core   +2 more sources

Evaluation of Interleukin17and Interleukin 23 expression in patients with active and latent tuberculosis infection [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s): Tuberculosis is one of the most important infectious diseases with high mortality rates worldwide, especially in developing countries. Interleukin17 (IL-17) is an important acquired immunity cytokine, which is mainly produced by CD4+TH17 ...
Fatemeh Heidarnezhad, Amir Asnaashari, Seyed Abdolrahim Rezaee, Roghayeh Ghezelsofla, Kiarash Ghazvini, Narges Valizadeh, Reza Basiri, Aghigh Ziaeemehr, Somayeh Sobhani, Houshang Rafatpanah   +9 more
doaj   +1 more source

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 [PDF]

, 2018
Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is ...
A Clayton, A Desmouliere, A Holmes, A Yabuki, AA Eddy, AA Eddy, AC Sanchez-Lara, BL Aken, C Grupp, C. P. D. Wheeler-Jones, CH Heldin, CL Marino, E Honda, E Van Obberghen-Schilling, F Strutz, F Strutz, F Syeda, GR Grotendorst, H. M. Syme, HP Rodemann, J Ivaska, J Lu, J. Elliott, J. S. Lawson, JL Mumaw, JS Lawson, K Sawashima, KG McCullagh, KJ Kelynack, LC Penning, M Prunotto, M Zeisberg, MA Venkatachalam, MJ Ryan, MK Phanish, ML Sequeira Lopez, P Boor, P Sysa, PC Bartlett, Q Chai, RA Ignotz, S Chakrabarti, S Meran, S Moll, S Neelisetty, SC Chen, SL Lin, SP DiBartola, SW Smith, T Akamatsu, TA Wynn, V Dugina, VS Lebleu, W Bloom, WA Border, X Pan, XM Meng, Y Hosokawa, Y Liu   +58 more
core   +2 more sources

Prostaglandins and chronic inflammation [PDF]

Trends in Pharmacological Sciences, 2012
Chronic inflammation is the basis of various chronic illnesses including cancer and vascular diseases. However, much has yet to be learned how inflammation becomes chronic. Prostaglandins (PGs) are well established as mediators of acute inflammation, and recent studies in experimental animals have provided evidence that they also function in transition
Aoki, Tomohiro, Narumiya, Shuh
openaire   +2 more sources

Circadian Oscillations of Minimal Erythema Dose (MED) are Also Influenced by Diet in Patients with Psoriasis: A Chronomedical Study

Dermatology and Therapy, 2023
Introduction Minimal erythema dose (MED) remains a parameter of paramount importance to orient narrow-band (NB)-UVB phototherapy in psoriatic (PsO) patients.
Giovanni Damiani, Alessia Pacifico, Egeria Scoditti, Sara di Gregorio, Massimo Del Fabbro, Claudia Cozzolino, Alessandra Buja, Santo R. Mercuri, Vittoria G. Bianchi, Ayman Grada, Sergio Garbarino, Christopher G. Bunick   +11 more
doaj   +1 more source

Enteric Tuft Cells in Host-Parasite Interactions

Pathogens, 2021
Enteric tuft cells are chemosensory epithelial cells gaining attention in the field of host-parasite interactions. Expressing a repertoire of chemosensing receptors and mediators, these cells have the potential to detect lumen-dwelling helminth and ...
Sruthi Rajeev, Olivia Sosnowski, Shuhua Li, Thibault Allain, André G. Buret, Derek M. McKay   +5 more
doaj   +1 more source

An immunocompromised dialysis patient with skin and bone lesions [PDF]

, 2010
Patients with chronic kidney failure have disturbances of immune function involving both innate and adaptive systems. These result in both immunodepression which increases susceptibility to infection and immunoactivation leading to a chronic inflammatory
Brown, Griffith, Jarzembowski, Katoch, Swenson, Uslan, Wallace, Wallace   +7 more
core   +2 more sources

The Expression and Regulation of Chemokines (CXCL9, CXCL10, CXCL11) in Urinary Bladder Inflammation of the Mouse [PDF]

, 2017
Interstitial cystitis is a serious chronic condition that causes bladder pain and increased voiding frequency in millions of adults in the US, most of them women.
Guo, Michael
core   +1 more source

Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells [PDF]

, 2018
Acute inflammation is a complex and tightly regulated homeostatic process that includes leukocyte migration from the vasculature into tissues to eliminate the pathogen/injury, followed by a pro-resolving response promoting tissue repair.
Achuthan, Alivernini, Alivernini, Alvaro-Gracia, Anderson, Asquith, Bamboat, Behrens, Bell, Ben Nasr, Benham, Black, Bluml, Brentano, Burmester, Burmester, Burmester, Catrina, Cauli, Cheung, Chu, Chu, Couzin-Frankel, Cramer, Cross, den Berg, den Brand, Dillon, Donlin, Ehrenstein, Elmesmari, Ferraccioli, Field, Firestein, Frank-Bertoncelj, Gao, Ginhoux, Greven, Guiducci, Guo, Hambleton, Hamilton, Haschka, Herenius, Hogg, Hurst, Iliev, James, Jongbloed, Kaplanski, Kokkonen, Kollias, Konig, Kriegler, Kurowska-Stolarska, Kurowska-Stolarska, Kurowska-Stolarska, Lemke, Malmstrom, Mann, McInnes, McInnes, McInnes, McLoughlin, Midwood, Miller, Misharin, Misso, Moret, Moret, Morton, Murata, Na, Nagy, Nassar, Ng, O'Connell, O'Connell, O'Keeffe, Ohshima, Okada, Paolino, Park, Rajasekhar, Ramwadhdoebe, Rauber, Reynolds, Roberts, Rothlin, Rupaimoole, Rycke, Sacre, Schett, Singh, Smith, Smith, Smolen, Sokolove, Stanczyk, Steidl, Takeuchi, Tannahill, Thai, Tsoumakidou, Udalova, Vandenabeele, Villani, Watts, Weinblatt, Weiss, Williamson, Wolf, Xiong, Yeo, Yu, Zou   +115 more
core   +1 more source