Results 11 to 20 of about 1,263,220 (260)
BMC Cancer, 2023 Background The lack of effective and accurate predictive indicators remains a major bottleneck for the improvement of the prognosis of patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Hepatitis B virus X (HBx) has been widely
Ming-Da Wang +6 more
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BMC Medical Genomics, 2019 Background Glucocorticoids act on the glucocorticoid receptor (GR; NR3C1) to resolve inflammation and, as inhaled corticosteroids (ICS), are the cornerstone of treatment for asthma. However, reduced efficacy in severe disease or exacerbations indicates a
Mahmoud M. Mostafa +7 more
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Wuzi Yanzong Pill relieves CPZ-induced demyelination by improving the microenvironment in the brain
Heliyon, 2022 Ethnopharmacology relevance: Wuzi Yanzong Pill (WYP), a well-known prescription for invigorating the kidney and essence, which is widely used to treat infertility such as oligoasthenospermia.
Yan-Rong Li +10 more
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Erythrocyte phospho-signalling is dynamically altered during infection with Plasmodium falciparum
Microbial Cell, 2020 It is well established that intracellular pathogens mobilise signalling pathways to manipulate gene expression of their host cell to promote their own survival.
Jack D. Adderley, Christian Doerig
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Chronic Inflammation in Cancer Development [PDF]
Frontiers in Immunology, 2012 Chronic inflammatory mediators exert pleiotropic effects in the development of cancer. On the one hand, inflammation favors carcinogenesis, malignant transformation, tumor growth, invasion, and metastatic spread; on the other hand inflammation can stimulate immune effector mechanisms that might limit tumor growth.
Gabriele eMulthoff +4 more
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Frontiers in Immunology, 2019 Background: Inflammatory bowel disease (IBD) is characterized by both acute and chronic phase inflammation of the gastro-intestinal (GI) tract that affect a large and growing number of people worldwide with little to no effective treatments.
Matthew Stephens +2 more
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Direct impact of commonly used dietary emulsifiers on human gut microbiota
Microbiome, 2021 Background Epidemiologic evidence and animal studies implicate dietary emulsifiers in contributing to the increased prevalence of diseases associated with intestinal inflammation, including inflammatory bowel diseases and metabolic syndrome.
Sabrine Naimi +3 more
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Microbiome, 2021 Background Studies on the inhibition of inflammation by infection with helminth parasites have, until recently, overlooked a key determinant of health: the gut microbiota.
Adam Shute +9 more
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Chronic inflammation and asthma
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2010 Allergic asthma is a complex and chronic inflammatory disorder which is associated with airway hyper-responsiveness and tissue remodelling of the airway structure. Although originally thought to be a Th2-driven inflammatory response to inhaled innocuous allergen, the immune response in asthma is now considered highly heterogeneous.
Murdoch, Jenna R., Lloyd, Clare M.
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Scientific Reports, 2018 Opioids remain the gold standard for the treatment of moderate to severe pain. However, their analgesic properties come with important side effects, including pruritus, which occurs frequently after systemic or neuraxial administration.
Helvira Melo +6 more
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