Results 11 to 20 of about 3,472,002 (291)
Nitric oxide in acute and chronic inflammation. [PDF]
, 2002 PhDNitric oxide (NO) is a signalling molecule formed when L-arginine is converted to L-citrulline by the enzyme NO synthase (NOS. NOS exists as three isoforms, ecNOS is constitutively expressed in endothelial cells and nNOS in neuronal cells, while a ...
Paul-Clark, Mark John
core +4 more sources
The role of airway infection in chronic obstructive pulmonary disease [PDF]
, 2006 PhDThis. thesis examines the role of respiratory bacterial and viral infection in the natural history of Chronic Obstructive Pulmonary Disease. The rationale for this study is basedu pon previous data demonstratingt hat airway bacterial colonisationi s
Wilkinson, Thomas Michael Alan
core +4 more sources
Inflammation in Chronic Wounds [PDF]
International Journal of Molecular Sciences, 2016 Non-healing chronic wounds present a major biological, psychological, social, and financial burden on both individual patients and the broader health system. Pathologically extensive inflammation plays a major role in the disruption of the normal healing cascade.
Ruilong Zhao +4 more
openaire +2 more sources
TLRs and chronic inflammation [PDF]
The International Journal of Biochemistry & Cell Biology, 2010 After the discovery of Toll-like receptors (TLRs), innate immune mechanisms came back in the focus of scientific research. With more and more mechanisms of TLR biology known, it has become clear that these and also other innate immune receptors are not only of crucial importance in the immune response to invading pathogens, but also play a role in the ...
Ospelt, C, Gay, S
openaire +4 more sources
High-Fat Diet : Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse [PDF]
, 2010 Background: Obesity induced by high fat (HF) diet is associated with inflammation which contributes to development of insulin resistance. Most prior studies have focused on adipose tissue as the source of obesity-associated inflammation.
Ding, Shengli +7 more
core +6 more sources
Prostaglandins and chronic inflammation [PDF]
Trends in Pharmacological Sciences, 2012 Chronic inflammation is the basis of various chronic illnesses including cancer and vascular diseases. However, much has yet to be learned how inflammation becomes chronic. Prostaglandins (PGs) are well established as mediators of acute inflammation, and recent studies in experimental animals have provided evidence that they also function in transition
Aoki, Tomohiro, Narumiya, Shuh
openaire +2 more sources
Acute and Chronic Effects of Smoking on Inflammation Markers in Exhaled Breath Condensate in Current Smokers [PDF]
, 2010 Background: Long-term cigarette smoking is associated with pulmonary inflammation, but the acute effects of smoking have been less well studied. Analysis of the exhaled breath condensate (EBC) can provide noninvasive markers that might be indicative of ...
Römmelt, Horst +6 more
core +1 more source
Glucocorticoids and chronic inflammation [PDF]
Rheumatology, 2016 Glucocorticoids are steroid hormones that once bound to their receptor interact with the DNA binding domain. Almost 1000-2000 genes are sensitive to their effects, including immune/inflammatory response genes. However, their role in pathophysiology and therapy is still debated.
Rainer H, Straub, Maurizio, Cutolo
openaire +3 more sources
Regulation of endothelial cell activity and vascular inflammation by shear stress [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Evans, PC +1 more
core +6 more sources
Models of chronic obstructive pulmonary disease [PDF]
, 2004 Chronic obstructive pulmonary disease (COPD) is a major global health problem and is predicted to become the third most common cause of death by 2020. Apart from the important preventive steps of smoking cessation, there are no other specific treatments ...
David A Groneberg +5 more
core +1 more source