Results 21 to 30 of about 3,472,002 (291)

Chronic inflammation as a molecular basis of nonalcoholic steatohepatitis : role of macrophages and fibroblasts in the liver [PDF]

open access: yes, 2020
2020-08The pathological spectrum of nonalcoholic fatty liver disease includes simple steatosis and nonalcoholic steatohepatitis (NASH), the latter of which is the leading cause of cirrhosis and hepatocellular carcinoma.
Itoh, Michiko   +2 more
core   +1 more source

Chronic Inflammation in Cancer Development [PDF]

open access: yesFrontiers in Immunology, 2012
Chronic inflammatory mediators exert pleiotropic effects in the development of cancer. On the one hand, inflammation favors carcinogenesis, malignant transformation, tumor growth, invasion, and metastatic spread; on the other hand inflammation can stimulate immune effector mechanisms that might limit tumor growth.
Gabriele eMulthoff   +4 more
openaire   +3 more sources

Mesenteric Lymphatic Alterations Observed During DSS Induced Intestinal Inflammation Are Driven in a TLR4-PAMP/DAMP Discriminative Manner

open access: yesFrontiers in Immunology, 2019
Background: Inflammatory bowel disease (IBD) is characterized by both acute and chronic phase inflammation of the gastro-intestinal (GI) tract that affect a large and growing number of people worldwide with little to no effective treatments.
Matthew Stephens   +2 more
doaj   +1 more source

Direct impact of commonly used dietary emulsifiers on human gut microbiota

open access: yesMicrobiome, 2021
Background Epidemiologic evidence and animal studies implicate dietary emulsifiers in contributing to the increased prevalence of diseases associated with intestinal inflammation, including inflammatory bowel diseases and metabolic syndrome.
Sabrine Naimi   +3 more
doaj   +1 more source

Cooperation between host immunity and the gut bacteria is essential for helminth-evoked suppression of colitis

open access: yesMicrobiome, 2021
Background Studies on the inhibition of inflammation by infection with helminth parasites have, until recently, overlooked a key determinant of health: the gut microbiota.
Adam Shute   +9 more
doaj   +1 more source

Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease [PDF]

open access: yes, 2011
Chronic obstructive pulmonary disease (COPD) is a global health problem. The current therapies for COPD are poorly effective and the mainstays of pharmacotherapy are bronchodilators.
Hongwei Yao   +3 more
core   +1 more source

Effect of inflammation on the relationship of pulse pressure and mortality in haemodialysis. [PDF]

open access: yes, 2011
The effect of hypertension on mortality in haemodialysis patients is controversial and can be confounded by non-traditional risk factors like systemic inflammation. This study examined the effect of systolic blood pressure (SBP), diastolic blood pressure
Herzog, CA, Collins, AJ, Banerjee, D
core   +1 more source

Chronic inflammation and asthma

open access: yesMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2010
Allergic asthma is a complex and chronic inflammatory disorder which is associated with airway hyper-responsiveness and tissue remodelling of the airway structure. Although originally thought to be a Th2-driven inflammatory response to inhaled innocuous allergen, the immune response in asthma is now considered highly heterogeneous.
Murdoch, Jenna R., Lloyd, Clare M.
openaire   +3 more sources

Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and alleviated by channel activation

open access: yesScientific Reports, 2018
Opioids remain the gold standard for the treatment of moderate to severe pain. However, their analgesic properties come with important side effects, including pruritus, which occurs frequently after systemic or neuraxial administration.
Helvira Melo   +6 more
doaj   +1 more source

Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN [PDF]

open access: yes, 2015
香川大学Kagawa University博士(医学)Abstract Chronic inflammatory effects of single intratracheal instillation (i.t.) of quartz on rat lung tumorigenesis were examined using 4 different animal models.
中野, 裕子   +2 more
core   +1 more source

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