Results 51 to 60 of about 2,740,979 (275)

Biventricular noncompaction cardiomyopathy with severe systolic and diastolic dysfunction in a systemic sclerosis patient

Türk Kardiyoloji Derneği Arşivi, 2015
Non-compaction cardiomyopathy (NCM) is a rare congenital cardiomyopathy characterized by deep increased trabeculation in one or more segments of the ventricle. The apical segment of the left ventricle is most commonly affected, but left ventricular basal
Belma Kalaycı, Süleyman Kalaycı, Turgut Karabağ, Mustafa Aydın   +3 more
doaj   +1 more source

Role of inflammation in diabetic cardiomyopathy

Therapeutic Advances in Endocrinology and Metabolism, 2022
The prevalence of type 2 diabetes (T2D) has reached a pandemic scale. Systemic chronic inflammation dominates the diabetes pathophysiology and has been implicated as a causal factor for the development of vascular complications.
Pranav Ramesh, Jian L. Yeo, Emer M. Brady, Gerry P. McCann   +3 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Immunosuppressive therapy in inflammatory cardiomyopathy

, 2002
The role of immunosuppressive treatment in inflammatory cardiomyopathy is still controversial. Nevertheless, it is recommended in patients with eosinophilic myocarditis, granulomatous myocarditis, giant-cell myocarditis and lymphocytic myocarditis ...
M. Pieroni, CHIMENTI, CRISTINA, FRUSTACI, ANDREA, A FRUSTACI, Pieroni, M   +4 more
core   +1 more source

Advances in understanding the role of adipose tissue and mitochondrial oxidative stress in Trypanosoma cruzi infection [version 1; peer review: 2 approved]

F1000Research, 2019
Trypanosoma cruzi, the etiologic agent of Chagas disease, causes a latent infection that results in cardiomyopathy. Infection with this pathogen is a major socio-economic burden in areas of endemic infection throughout Latin America.
Jyothi F. Nagajyothi, Louis M. Weiss
doaj   +1 more source

Anti-inflammatory Role of Galectin-8 During Trypanosoma cruzi Chronic Infection

Frontiers in Cellular and Infection Microbiology, 2020
Galectins are animal lectins with high affinity for β-galactosides that drive the immune response through several mechanisms. In particular, the role of galectin-8 (Gal-8) in inflammation remains controversial.
Adriano Bertelli, Adriano Bertelli, Liliana M. Sanmarco, Liliana M. Sanmarco, Liliana M. Sanmarco, Carla A. Pascuale, Carla A. Pascuale, Miriam Postan, Miriam Postan, Maria P. Aoki, Maria P. Aoki, Maria P. Aoki, María S. Leguizamón, María S. Leguizamón   +13 more
doaj   +1 more source

SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease. [PDF]

PLoS Pathogens, 2016
Chronic chagasic cardiomyopathy (CCM) is presented by increased oxidative/inflammatory stress and decreased mitochondrial bioenergetics. SIRT1 senses the redox changes and integrates mitochondrial metabolism and inflammation; and SIRT1 deficiency may be ...
Xianxiu Wan, Jian-Jun Wen, Sue-Jie Koo, Lisa Yi Liang, Nisha Jain Garg   +4 more
doaj   +1 more source

Anti-inflammatory and pro-angiogenic effects of beta blockers in a canine model of chronic ischemic cardiomyopathy: comparison between carvedilol and metoprolol [PDF]

Basic Research in Cardiology, 2013
There is controversy regarding the superiority of carvedilol (C) over metoprolol (M) in congestive heart failure. We hypothesized that C is superior to M in chronic ischemic cardiomyopathy because of its better anti-inflammatory and pro-angiogenic effects.
Le D. E., Pascotto M., Leong-Poi H., Sari I., Micari A., Kaul S.   +5 more
openaire   +3 more sources

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Changes of biventricular contractile function depending on the types of left ventricular involvement in patients 1 year after COVID-19 pneumonia

Российский кардиологический журнал
Aim. To study the changes of biventricular contractile function depending on the types of left ventricular involvement according to the speckle tracking echocardiography (STE).Material and methods.
N. E. Shirokov, E. I. Yaroslavskaya, D. V. Krinochkin, N. A. Osokina, E. A. Gorbatenko, I. O. Korovina, A. V. Migacheva   +6 more
doaj   +1 more source