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Pathophysiology of chronic kidney disease-mineral and bone disorder
Joint Bone Spine, 2012Chronic kidney disease (CKD) alters the metabolism of several minerals, thereby inducing bone lesions and vessel-wall calcifications that can cause functional impairments and excess mortality. The histological bone abnormalities seen in CKD, known as renal osteodystrophy, consist of alterations in the bone turnover rate, which may be increased ...
Fabrice, Mac Way +2 more
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Chronic Kidney Disease: Mineral and Bone Disorder (CKD-MBD)
2014Chronic kidney disease mineral and bone disorder (CKD-MBD) is defined as a systemic disorder of mineral and bone metabolism due to CKD comprising either one or a combination of the following:
Richard S. Fish, John Cunningham
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Calcimimetics in the Chronic Kidney Disease-Mineral and Bone Disorder
The International Journal of Artificial Organs, 2009Mineral and bone disorders (MBD) are both an early and very common complication of chronic kidney disease (CKD). It is now accepted that they represent a significant risk factor, explaining the high cardiovascular morbidity and mortality in CKD patients. During the last decade, we have been witnessing many advances in the nomenclature, classification,
Jordi, Bover +11 more
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Pathophysiology of chronic kidney disease-mineral and bone disorder
2015Abstract Chronic kidney disease is associated with the inability to control normal mineral homeostasis, resulting in abnormalities in serum levels of calcium, phosphorus, parathyroid hormone, fibroblast growth factor 23 (FGF23) and vitamin D metabolism. These disturbances lead to the development of secondary hyperparathyroidism, skeletal
Ezequiel Bellorin-Font +4 more
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Chronic kidney disease-mineral and bone disorder
JAAPA, 2016ABSTRACT Chronic kidney disease affects 23 million Americans and is associated with many complications, one of the most complex of which is mineral and bone disorder. Pathophysiologic mechanisms begin to occur early in CKD but when the glomerular filtration rate declines to <50% of normal, biochemical and bone matrix abnormalities, which ...
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Management of chronic kidney disease-mineral and bone disorder
2015Abstract In all patients with chronic kidney disease (CKD) stages 3–5, regular monitoring of serum markers of CKD-mineral and bone disorder, including calcium (Ca), phosphorus (P), parathyroid hormone (PTH), 25-hydroxyvitamin D, and alkaline phosphatase, is recommended. Target ranges for these markers are endorsed by guidelines.
Thanh-Mai Vo +2 more
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Clinical calcium, 2010
Disturbances in bone and mineral metabolism in patients with chronic kidney disease (CKD) affect not only the bone diseases but also other organ disorders in the whole body and deteriorate the survival of these patients. The term CKD-Mineral and Bone Disorder (CKD-MBD) has been established describing a broader clinical syndrome that develops as a ...
Masahide, Mizobuchi +2 more
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Disturbances in bone and mineral metabolism in patients with chronic kidney disease (CKD) affect not only the bone diseases but also other organ disorders in the whole body and deteriorate the survival of these patients. The term CKD-Mineral and Bone Disorder (CKD-MBD) has been established describing a broader clinical syndrome that develops as a ...
Masahide, Mizobuchi +2 more
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THE ASSOCIATION OF CHRONIC KIDNEY DISEASE‐MINERAL BONE DISORDER AND CARDIOVASCULAR RISK
Journal of Renal Care, 2010SUMMARYChronic kidney disease‐mineral bone disorder (CKD‐MBD) is a multifaceted definition used to help describe the systemic derangement of mineral bone metabolism in renal disease. This was previously referred to, rather simplistically, as ‘renal osteodystrophy’ or ‘renal bone disease’.
Eddington, Helen, Kalra, Philip A.
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Management of chronic kidney disease-mineral and bone disorder
2018In all patients with chronic kidney disease (CKD) stages 3–5, regular monitoring of serum markers of CKD-mineral and bone disorder, including calcium (Ca), phosphorus (P), parathyroid hormone (PTH), 25-hydroxyvitamin D, and alkaline phosphatase, is recommended. Target ranges for these markers are endorsed by guidelines.
Alexandra Voinescu +2 more
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[Chronic kidney disease-mineral and bone disorder (CKD-MBD)].
Nihon rinsho. Japanese journal of clinical medicine, 2006Changes in mineral and bone metabolism are prevalent in chronic kidney disease. There are several types of renal bone disease, called 'renal osteodystrophy (ROD)'. ROD includes osteitis fibrosa, osteomalacia, adynamic bone disorder, and mixed osteodystrophy. Osteitis fibrosa is high turnover bone due to secondary hyperparathyroidism.
Yasuhiro, Hamada, Masafumi, Fukagawa
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