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Chronic kidney disease is highly prevalent (10-13% of the population), irreversible, progressive, and associated with higher cardiovascular risk. Patients with this pathology remain asymptomatic most of the time, presenting the complications typical of renal dysfunction only in more advanced stages.
Cornelia, Charles, Allison H, Ferris
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The definition and classification of chronic kidney disease (CKD) have evolved over time, but current international guidelines define this condition as decreased kidney function shown by glomerular filtration rate (GFR) of less than 60 mL/min per 1·73 m2, or markers of kidney damage, or both, of at least 3 months duration, regardless of the underlying ...
Angela C, Webster +3 more
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Chronic kidney disease is a progressive disease with no cure and high morbidity and mortality that occurs commonly in the general adult population, especially in people with diabetes and hypertension. Preservation of kidney function can improve outcomes and can be achieved through non-pharmacological strategies (eg, dietary and lifestyle adjustments ...
Kalantar-Zadeh, Kamyar +4 more
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In his review article in the March 2015 edition ofCME, Prof. A M Meyers refers to chronic kidneydisease as 'an important disease group that threatenshealth'. I fully concur with this observation andwish to go a step further and assert that kidneydisease, together with other related non-communicable diseases(NCDs), poses not only a threat to health but ...
Catherine E. Langston, Adam E. Eatroff
+14 more sources
This issue provides a clinical overview of chronic kidney disease, focusing on prevention, diagnosis, treatment, and patient information. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including ACP Smart Medicine and MKSAP (Medical Knowledge and Self-Assessment ...
Paul, Drawz, Mahboob, Rahman
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Chronic Kidney Disease-Associated Pruritus [PDF]
Pruritus is a distressing condition associated with end-stage renal disease (ESRD), advanced chronic kidney disease (CKD), as well as maintenance dialysis and adversely affects the quality of life (QOL) of these patients. It has been reported to range from 20% to as high as 90%.
Puneet Agarwal +5 more
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Chronic kidney disease is a condition that affects thousands of children all over the world, compromising their health and quality of life. Recent epidemiological studies have provided evidence suggesting that the number of patients is expected to grow.
Mencarelli F., Busutti M., Montini G.
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Adiponectin in Chronic Kidney Disease [PDF]
Adiponectin is the adipokine associated with insulin sensitization, reducing liver gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. Adiponectin is present in the kidneys, mainly in the arterial endothelium and smooth muscle cells, as well as in the capillary endothelium, and might be considered as a marker of many negative ...
Jarosław Przybyciński +4 more
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Potassium voltage-gated channel subfamily Q member 1 (KCNQ1) is one of the strongest susceptibility genes for type 2 diabetes mellitus (T2DM). Association studies between KCNQ1 genetic variants and T2DM have been reported. The multifactorial disease T2DM
Ji Young Park +4 more
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Chronic Kidney Disease Progression [PDF]
Whether we like it or not, nephrologists around the world have been called to action. Our mission is to attenuate the growth of chronic kidney disease (CKD). Several conditions will need to gel for us to succeed.
Allison A, Eddy, Eric G, Neilson
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