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The Podocyte in Diabetic Kidney Disease
Approaching epidemic levels, diabetic kidney disease (DKD) is now the leading cause of end-stage renal disease (ESRD). Microalbuminuria is an early clinical marker of DKD that results from damage to the glomerular filtration barrier at the level of the ...
Erin Stitt-Cavanagh+2 more
doaj +1 more source
Background Reportedly, dialysis solutions containing molecular hydrogen (H2) might ameliorate patient-reported fatigue in hemodialysis (HD) patients. However, it is unknown whether its impact might differ with different H2 levels. Method This single-arm,
Susumu Uemura+8 more
doaj +1 more source
Kidney age, not kidney disease [PDF]
Chronic kidney disease stages 1 to 4 are asymptomatic health states that are not “disease” according to previously proposed definitions of disease. Reduced kidney function levels, currently called chronic kidney disease, are not abnormal in older age ...
Evans, Julie+10 more
core +4 more sources
Prediction of Chronic Kidney Disease - A Machine Learning Perspective
Chronic Kidney Disease is one of the most critical illness nowadays and proper diagnosis is required as soon as possible. Machine learning technique has become reliable for medical treatment. With the help of a machine learning classifier algorithms, the
Pankaj Chittora+10 more
semanticscholar +1 more source
Molecular Mechanisms of Kidney Injury and Repair in Arterial Hypertension [PDF]
The global burden of chronic kidney disease is rising. The etiologies, heterogeneous, and arterial hypertension, are key factors contributing to the development and progression of chronic kidney disease. Arterial hypertension is induced and maintained by
Eckardt, Kai-Uwe+1 more
core +2 more sources
Probiotics and chronic kidney disease [PDF]
Probiotics are the focus of a thorough investigation as a natural biotreatment due to their various health-promoting effects and inherent ability to fight specific diseases including chronic kidney disease (CKD). Indeed, intestinal microbiota has recently emerged as an important player in the progression and complications of CKD.
Koppe, L., Mafra, D., Fouque, Denis
openaire +4 more sources
Climate change and the kidney [PDF]
The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality.
Butler-Dawson, Jaime+12 more
core +1 more source
Chronic kidney disease is a worldwide public health problem. In the United States, the incidence and prevalence of kidney failure are rising, the outcomes are poor, and the costs are high.
A. Levey+9 more
semanticscholar +1 more source
Dysregulation of autophagy-mediated podocyte homeostasis is proposed to play a role in idiopathic membranous nephropathy (IMN). In the present study, autophagic activity and lysosomal alterations were investigated in podocytes of IMN patients and in ...
Wei Jing Liu+9 more
doaj +1 more source
Background Glutamate is a major neurotransmitter, although it causes cytotoxicity and inflammation in nonneuronal organs. This study aimed to investigate the metabolic disorders in which glutamate, associated with type 2 diabetes onset, is induced in the
Hyo Jung Lee+7 more
doaj +1 more source