Results 41 to 50 of about 2,709,162 (390)

ACE2 deficiency exacerbates obesity-related glomerulopathy through its role in regulating lipid metabolism

Cell Death Discovery, 2022
Obesity-related glomerulopathy is a secondary glomerular disease and its incidence has been increased globally in parallel with the obesity epidemic. ORG emerged as a growing cause of end-stage renal disease in recent years.
Yin-Yin Chen, Han Hong, Yu-Ting Lei, Jia Zou, Yi-Ya Yang, Li-Yu He   +5 more
doaj   +1 more source

Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease.

New England Journal of Medicine, 2020
BACKGROUND The efficacy and safety of sodium-glucose cotransporter 2 inhibitors such as sotagliflozin in preventing cardiovascular events in patients with diabetes with chronic kidney disease with or without albuminuria have not been well studied ...
Deepak L. Bhatt, M. Szarek, B. Pitt, C. Cannon, Lawrence A Leiter, Darren K Mcguire, J. Lewis, M. Riddle, S. Inzucchi, M. Kosiborod, D. Cherney, J. Dwyer, B. Scirica, C. Bailey, R. Diaz, K. Ray, J. Udell, R. Lopes, P. Lapuerta, P. Steg   +19 more
semanticscholar   +1 more source

Antiplatelet therapy for the prevention of atherosclerosis in chronic kidney disease (ALTAS-CKD) patients: study protocol for a randomized clinical trial

Trials, 2021
Background Cardiovascular disease (CVD) is the most common complication and the leading cause of death in patients with chronic kidney disease (CKD).
Jiachuan Xiong, Ting He, Zhikai Yu, Ke Yang, Feng Chen, Jingbo Cheng, Yu Shi, Yinghui Huang, Yu Qiao, Haiyang Li, Yunzhu Shen, Jinghong Zhao   +11 more
doaj   +1 more source

Patient Activation with Knowledge, Self-Management, and Confidence in Chronic Kidney Disease [PDF]

, 2015
Background Chronic kidney disease is a growing health problem on a global scale. The increasing prevalence of chronic kidney disease presents an urgent need to better understand the knowledge, confidence and engagement in self-managing the disease ...
Hertzog, Melody, Johnson, Michelle L., Plumb, Troy, Pozehl, Bunny, Welch, Janet L., Zimmerman, Lani   +5 more
core   +1 more source

Wasting in chronic kidney disease [PDF]

Journal of Cachexia, Sarcopenia and Muscle, 2011
Wasting/cachexia is prevalent among patients with chronic kidney disease (CKD). It is to be distinguished from malnutrition, which is defined as the consequence of insufficient food intake or an improper diet. Malnutrition is characterized by hunger, which is an adaptive response, whereas anorexia is prevalent in patients with wasting/cachexia.
Kamyar Kalantar-Zadeh, Kamyar Kalantar-Zadeh, Dominic S. Raj, Robert H. Mak, Robert H. Mak, Csaba P. Kovesdy, Csaba P. Kovesdy, Alp Ikizler, Peter Stenvinkel   +8 more
openaire   +5 more sources

Impact of hemodialysis solutions containing different levels of molecular hydrogen (H2) on the patient-reported outcome of fatigue

Renal Replacement Therapy, 2022
Background Reportedly, dialysis solutions containing molecular hydrogen (H2) might ameliorate patient-reported fatigue in hemodialysis (HD) patients. However, it is unknown whether its impact might differ with different H2 levels. Method This single-arm,
Susumu Uemura, Yoshitaka Kegasa, Keigo Tada, Taichi Tsukahara, Shigeru Kabayama, Tae Yamamoto, Mariko Miyazaki, Joji Takada, Masaaki Nakayama   +8 more
doaj   +1 more source

Chronic Kidney Disease

Journal of Atherosclerosis and Thrombosis, 2014
Chronic kidney disease is a condition that affects thousands of children all over the world, compromising their health and quality of life. Recent epidemiological studies have provided evidence suggesting that the number of patients is expected to grow.
Mencarelli F., Busutti M., Montini G.
openaire   +4 more sources

Oxidative Stress and Mitochondrial Dysfunction in Chronic Kidney Disease

Cells, 2022
The kidney contains many mitochondria that generate ATP to provide energy for cellular processes. Oxidative stress injury can be caused by impaired mitochondria with excessive levels of reactive oxygen species.
Hsin-Jung Ho, H. Shirakawa
semanticscholar   +1 more source

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 [PDF]

, 2018
Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is ...
A Clayton, A Desmouliere, A Holmes, A Yabuki, AA Eddy, AA Eddy, AC Sanchez-Lara, BL Aken, C Grupp, C. P. D. Wheeler-Jones, CH Heldin, CL Marino, E Honda, E Van Obberghen-Schilling, F Strutz, F Strutz, F Syeda, GR Grotendorst, H. M. Syme, HP Rodemann, J Ivaska, J Lu, J. Elliott, J. S. Lawson, JL Mumaw, JS Lawson, K Sawashima, KG McCullagh, KJ Kelynack, LC Penning, M Prunotto, M Zeisberg, MA Venkatachalam, MJ Ryan, MK Phanish, ML Sequeira Lopez, P Boor, P Sysa, PC Bartlett, Q Chai, RA Ignotz, S Chakrabarti, S Meran, S Moll, S Neelisetty, SC Chen, SL Lin, SP DiBartola, SW Smith, T Akamatsu, TA Wynn, V Dugina, VS Lebleu, W Bloom, WA Border, X Pan, XM Meng, Y Hosokawa, Y Liu   +58 more
core   +2 more sources

Exploring metabolic dysfunction in chronic kidney disease [PDF]

, 2012
Impaired kidney function and chronic kidney disease (CKD) leading to kidney failure and end-stage renal disease (ESRD) is a serious medical condition associated with increased morbidity, mortality, and in particular cardiovascular disease (CVD) risk ...
Slee, Adrian D.
core   +2 more sources