Results 71 to 80 of about 2,456,607 (422)
A review on the classification and current treatment of Chronic Kidney Disease [PDF]
, 2023 Introduction: Chronic Kidney Disease (CKD) is a chronic condition which is characterized by the gradual loss of kidney function over time leading to End-Stage Renal Disease (ESRD). Role of kidneys is very vital to maintain homeostasis of the system.
Jakubowska, Wiktoria +7 more
core +1 more source
Acute kidney injury and chronic kidney disease as interconnected syndromes.
New England Journal of Medicine, 2014 For more than 40 years, nephrologists have classified diminished kidney function as two distinct syndromes — acute and chronic kidney failure. Whereas chronic kidney disease was recognized in the 19th century, acute renal dysfunction became evident ...
L. Chawla, P. Eggers, R. Star, P. Kimmel
semanticscholar +1 more source
Frontiers in Immunology, 2020 Pathogenic autoantibodies can cause inflammation and tissue injury in systemic lupus erythematosus (SLE). Although IgG4 is considered non-inflammatory owing to the unique structure of its hinge region, the role of IgG4 autoantibodies in SLE remains ...
Qingjun Pan +9 more
doaj +1 more source
Transformer-based Time-to-Event Prediction for Chronic Kidney Disease Deterioration [PDF]
, 2023 Deep-learning techniques, particularly the transformer model, have shown great potential in enhancing the prediction performance of longitudinal health records. While previous methods have mainly focused on fixed-time risk prediction, time-to-event prediction (also known as survival analysis) is often more appropriate for clinical scenarios.
arxiv +1 more source
Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]
, 2005 Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Anders, Hans-Joachim, Ninichuk, Volha
core +1 more source
Chronic Kidney Disease Diagnosis and Management: A Review.
Journal of the American Medical Association (JAMA), 2019 Importance Chronic kidney disease (CKD) is the 16th leading cause of years of life lost worldwide. Appropriate screening, diagnosis, and management by primary care clinicians are necessary to prevent adverse CKD-associated outcomes, including ...
Teresa K. Chen, D. H. Knicely, M. Grams
semanticscholar +1 more source
Chronic kidney disease is associated with severe coronavirus disease 2019 (COVID-19) infection
International Urology and Nephrology, 2020 As the novel Coronavirus Disease 2019 (COVID-19) outbreak expands, identification of predictive factors for severe infection is essential to enable risk stratification, optimize reallocation of hospital resource, and guide public health recommendations ...
B. Henry, G. Lippi
semanticscholar +1 more source
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source
Chronic Kidney Disease of Unknown aetiology (CKDu) and multiple-ion interactions in drinking water [PDF]
Environmental Geochemistry and Health 1st September (2017), 2017 Recent experimental work on the nephrotoxicity of contaminants in drinking water using laboratory mice, motivated by the need to understand the origin of chronic kidney disease of unknown aetiology is examined within our understanding of the hydration of ions and proteins.
arxiv +1 more source
Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]
, 2014 Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G. +6 more
core +1 more source