Results 1 to 10 of about 795,396 (307)

Angiogenesis in chronic liver disease

open access: hybridAnnals of Hepatology, 2007
Chronic liver disease is characterized by inflammation and fibrosis. As a consequence angiogenesis leading to new vasculature may have prognostic value in disease progression. Interfering with angiogenesis may be a potential target to avoid progression of liver disease. Hence we planned to evaluate the CD34 and vascular endothelial growth factor (VEGF),
Anjali Amarapurkar   +3 more
openalex   +4 more sources

MicroRNA-29c Acting on FOS Plays a Significant Role in Nonalcoholic Steatohepatitis Through the Interleukin-17 Signaling Pathway

open access: yesFrontiers in Physiology, 2021
Nonalcoholic fatty liver disease is the most common hepatic disease in western countries and is even more ubiquitous in Asian countries. Our study determined that TH17/Treg cells were imbalanced in animal models.
Chao Cai   +13 more
doaj   +1 more source

Evaluation of the inhibitory effect of azoles on pharmacokinetics of lenvatinib in rats both in vivo and in vitro by UPLC‐MS/MS

open access: yesThoracic Cancer, 2023
Background Lenvatinib is a multitargeted tyrosine kinase inhibitor used in the treatment of a variety of solid tumors. This study aims to investigate the potential pharmacokinetic interactions between lenvatinib and various azoles (ketoconazole ...
Mengming Xia   +9 more
doaj   +1 more source

Increased INR Values Predict Accelerating Deterioration and High Short-Term Mortality Among Patients Hospitalized With Cirrhosis or Advanced Fibrosis

open access: yesFrontiers in Medicine, 2021
Background and Objective: An increase in the international normalized ratio (INR) is associated with increased mortality in patients with cirrhosis and other chronic liver diseases, while little is known about the quantitative relationship.
Ying Wang   +85 more
doaj   +1 more source

Coagulopathy of Chronic Liver Disease [PDF]

open access: yesNew England Journal of Medicine, 2011
[No abstract available]
VIOLI, Francesco   +2 more
openaire   +6 more sources

CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway

open access: yesJournal of Translational Medicine, 2023
Background Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide because of rapid progression and high incidence of metastasis or recurrence.
Chuanzheng Wang   +7 more
doaj   +1 more source

Baseline Neutrophil-to-Lymphocyte Ratio Is Independently Associated With 90-Day Transplant-Free Mortality in Patients With Cirrhosis

open access: yesFrontiers in Medicine, 2021
Background: Patients with cirrhosis have an increased risk of short-term mortality, however, few studies quantify the association between neutrophil-to-lymphocyte ratio (NLR) and 90-day transplant-free mortality in cirrhotic patients.Methods: We ...
Jing Liu   +58 more
doaj   +1 more source

Heat shock protein HSPA13 promotes hepatocellular carcinoma progression by stabilizing TANK

open access: yesCell Death Discovery, 2023
HSPA13, an important member of the heat shock protein family, plays an essential role in the oncogenesis of many organs, but the mechanism and function in hepatocellular carcinoma (HCC) is still unclear.
Xuesong Cen   +9 more
doaj   +1 more source

The Circulating miRNA Profile of Chronic Hepatitis D and B Patients Is Comparable but Differs from That of Individuals with HBeAg-Negative HBV Infection

open access: yesViruses, 2023
miRNAs circulating in whole serum and HBsAg-particles are differentially expressed in chronic hepatitis B (CHB) and HBeAg-negative-HBV infection (ENI); their profiles are unknown in chronic hepatitis D (CHD).
Daniela Cavallone   +9 more
doaj   +1 more source

Opportunities and Challenges of Surveillance for Liver Cancer in Primary Care Institutions in China [PDF]

open access: yesZhongguo quanke yixue, 2023
Primary liver cancer (PLC) is one of the common malignant tumors and the main causes of tumor death in China. Although the diagnosis and treatment technology of PLC in China has made great progress in recent years, its morbidity and mortality have been ...
WANG Shiyue, DONG Chen, CHANG Chudi, NAN Yuemin
doaj   +1 more source

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