Results 81 to 90 of about 1,228,703 (311)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Takotsubo Cardiomyopathy Secondary to Lung Transplantation Followed by Reduced Ejection Fraction Heart Failure: A Case Report

open access: yesClinical Case Reports
Takotsubo cardiomyopathy (TTC) is characterized by acute, transient left ventricular systolic dysfunction with regional wall‐motion abnormalities. It is a form of stress‐induced cardiomyopathy and can happen due to emotional or physical stress.
Azadeh Moradkhani   +10 more
doaj   +1 more source

Missed bronchial web in a 4‐year‐old boy with foreign body aspiration: A case report

open access: yesClinical Case Reports, 2023
Congenital bronchial webs are extremely rare and usually remain undiagnosed due to nonspecific symptoms. Herein, we reported a 4‐year‐old case of the bronchial web who was initially undiagnosed upon bronchoscopy following foreign body aspiration and ...
Mahsa Mirzandeh del   +4 more
doaj   +1 more source

Estimating The Annual Cost of Smoking-Related Diseases in Indonesia [PDF]

open access: yes, 2009
Background: Smoking plays a role in the development of chronic diseases and causes substantial negative economic consequences. This study was carried out to estimate the annual cost of smoking-related cardio-cerebrovascular and pulmonary diseases in ...
Hudoyo, Ahmad   +6 more
core   +1 more source

New targets for resolution of airway remodeling in obstructive lung diseases. [PDF]

open access: yes, 2018
Airway remodeling (AR) is a progressive pathological feature of the obstructive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
Deshpande, Deepak A.   +2 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Application of artificial neural network model in studying the mechanism of disease relapse event in patients with tuberculosis [PDF]

open access: yesHealth Science Monitor, 2022
Background & Aims: Today, due to progressing technology and improving the standard of living of humans, the study of diseases has become more complex.
Mehdi Kazempour Dizaji   +12 more
doaj  

The dendritic cell niche in chronic obstructive pulmonary disease. [PDF]

open access: yes, 2012
The pulmonary innate immune system is heavily implicated in the perpetual airway inflammation and impaired host defense characterizing Chronic Obstructive Pulmonary Disease (COPD).
Haczku, Angela
core   +3 more sources

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Eighty Kilograms Weight Reduction in a Case of Obstructive Sleep Apnea with Several Comorbidities: Did the Conditions Improve?

open access: yesActa Medica Iranica, 2016
Obstructive sleep apnea (OSA) together with metabolic disorders is common in severely obese patients. Weight reduction is considered as a treatment modality in these cases while few of them can succeed in considerable weight loss.
Moein Foroughi   +2 more
doaj  

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