Results 1 to 10 of about 46,104 (207)

Regularities of cytokine status changes in chronic lymphocytic leukaemia and their role in pathogenesis of progressive forms of disease [PDF]

open access: yesСаратовский научно-медицинский журнал, 2012
The aim of the research is to study and to analyze results of investigations of cytokine blood profile in patients with B-cellular chronic lymphocytic leukaemia.
Shelekhova T.V.   +2 more
doaj   +2 more sources

The impact of pausing Bruton Tyrosine Kinase inhibitor (BTKi) therapy versus continued therapy on vaccination immune response in patients with chronic lymphocytic leukaemia: the IMPROVE RCT

open access: yesEfficacy and Mechanism Evaluation
Background Chronic lymphocytic leukaemia is the most common leukaemia subtype and associated with profound immunosuppression. Bruton Tyrosine Kinase inhibitors have revolutionised chronic lymphocytic leukaemia management; however, Bruton Tyrosine Kinase ...
Jonathan A Cook   +16 more
doaj   +2 more sources

Haematological Malignancy Presenting in an Unusual Manner [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Chronic lymphocytic leukaemia is a haematological malignancy that occurs due to an increased proliferation of mature B lymphocytes. It is considered to be the most common leukaemia in adults. Hyponatraemia is commonly seen in such patients.
Ponvijaya Muthuswamy Yadav   +4 more
doaj   +1 more source

Chronic Lymphocytic Leukaemia Unmasked by COVID-19 Infection: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Corona Virus Disease 2019 (COVID-19) caused by SARS Cov-2 is an Ribonucleic Acid (RNA) virus which spreads through respiratory route. It was first detected in Wuhan, China in December 2019.
BHUMIKA GUPTA   +4 more
doaj   +1 more source

Chronic lymphocytic leukaemia [PDF]

open access: yesNature Reviews Disease Primers, 2017
Chronic lymphocytic leukaemia (CLL) is a malignancy of CD5+ B cells that is characterized by the accumulation of small, mature-appearing lymphocytes in the blood, marrow and lymphoid tissues. Signalling via surface immunoglobulin, which constitutes the major part of the B cell receptor, and several genetic alterations play a part in CLL pathogenesis ...
Stevenson, Freda   +8 more
openaire   +8 more sources

Chronic lymphocytic leukaemia [PDF]

open access: yesClinical Medicine, 2001
Le tableau clinique, le diagnostic et les differents traitements de la leucemie lymphocytaire chronique sont ...
C, Singer, T, Goldstone
openaire   +2 more sources

Synchronous metastatic cutaneous squamous cell carcinoma and chronic lymphocytic leukaemia/small lymphocytic lymphoma in a cervical lymph node: case report of an unusual event [PDF]

open access: yes, 2015
The synchronous occurrence of two different neoplasias is an uncommon event, which may arise between tumors originating in the same organ or in cancer-to-cancer metastasis.
Altemani, Albina   +3 more
core   +4 more sources

Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukemia

open access: yesHaematologica, 2020
Retrotransposons such as LINE-1 and Alu comprise >25% of the human genome. While global hypomethylation of these elements has been widely reported in solid tumours, their epigenetic dysregulation is yet to be characterised in chronic lymphocytic ...
Timothy M. Barrow   +6 more
doaj   +1 more source

Leukaemia Cutis: Clinical Features and Outcomes of 56 Patients

open access: yesActa Dermato-Venereologica, 2022
Leukaemia is a malignant neoplasm of the haematopoietic system. Cutaneous manifestations of leukaemia are called leukaemia cutis, and are regarded as a sign of poorer prognosis and shorter survival time.
Hwa Jung Yook   +8 more
doaj   +1 more source

Prolegomenon for Chronic Lymphocytic Leukaemia [PDF]

open access: yesScandinavian Journal of Immunology, 2003
AbstractChronic lymphocytic leukaemia (CLL) is a unique lymphoproliferative disorder that scarcely occurs under the age of 40; thereafter the incidence of CLL increases exponentially with age. CLL is characterized by progressive expansion of malignant CD5+ME+ B‐cell clone accompanied by a myriad of cellular and humoral immune defects.
Vitale, Branko   +7 more
openaire   +3 more sources

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