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Clinics in Geriatric Medicine, 1985
Chronic lymphocytic leukemia is a neoplasm characterized by the accumulation of monoclonal lymphocytes in blood, bone marrow, and other tissues. Staging of the disease is based on lymphoid mass and the presence of anemia or thrombocytopenia, with prognosis also related to the pattern of bone-marrow involvement, chromosomal abnormalities, and surface ...
Robert L. Stahl, Robert Silber
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Chronic lymphocytic leukemia is a neoplasm characterized by the accumulation of monoclonal lymphocytes in blood, bone marrow, and other tissues. Staging of the disease is based on lymphoid mass and the presence of anemia or thrombocytopenia, with prognosis also related to the pattern of bone-marrow involvement, chromosomal abnormalities, and surface ...
Robert L. Stahl, Robert Silber
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Chemoimmunotherapy of chronic lymphocytic leukemia
Nature Reviews Clinical Oncology, 2007The past two decades have seen a major paradigm shift in the therapy of chronic lymphocytic leukemia (CLL), with the treatment goal shifting from symptom palliation to the attainment of maximal disease control using the most effective frontline regimens available, thus prolonging survival and possibly leading to cure.
Michael J. Keating, Constantine S. Tam
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Transplantation in chronic lymphocytic leukemia
Current Hematologic Malignancy Reports, 2007Although there have been no randomized trials comparing the outcome of stem cell transplantation (SCT) with standard chemotherapy for patients with chronic lymphocytic leukemia (CLL), increasingly, both autologous and allogeneic SCT approaches are being explored in this disease.
John G. Gribben, Rifca Le Dieu
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Immunophenotyping of Chronic Lymphocytic Leukemia
Clinical Laboratory, 2017Chronic Lymphocytic Leukemia (CLL) is one of the most common diagnoses made by flow cytometry laboratories. There is no consensus on which markers need to be used in flow cytometry for accurate immunophenotyping. Herein, we investigated the role of markers used in flow cytometry in the distinction between CLL and MCL.A total 339 recently diagnosed B ...
Falay, Mesude, Ozet, GÜLSÜM
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[Chronic lymphocytic leukemia].
[Rinsho ketsueki] The Japanese journal of clinical hematology, 2014Currently, several novel drugs are available for chronic lymphocytic leukemia (CLL) in Western countries. Of these drugs, those that inhibit the B-cell receptor (BCR) signaling pathway are the most promising. Ibrutinib inhibits BTK in the BCR pathway and can be administered orally. The results of several clinical trials suggest that ibrutinib is highly
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The American Journal of the Medical Sciences, 1994
Ronald P. McCaffrey +2 more
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Ronald P. McCaffrey +2 more
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