Results 311 to 320 of about 281,573 (395)

Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

Cell, 2012
D. Landau, S. Carter, P. Stojanov, A. McKenna, K. Stevenson, M. Lawrence, C. Sougnez, C. Stewart, A. Sivachenko, Lili Wang, Youzhong Wan, Wandi Zhang, S. Shukla, Alexander Vartanov, S. Fernandes, G. Saksena, K. Cibulskis, B. Tesar, S. Gabriel, N. Hacohen, M. Meyerson, E. Lander, D. Neuberg, Jennifer R. Brown, G. Getz, Catherine J. Wu   +25 more
semanticscholar   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

VIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma, Junxin Chen, Yuan Du, Zhihao Cao, Weizhi Ji, Yuyu Niu, Zebin Yang   +6 more
wiley   +1 more source

The Elevation and Impact of Peripheral Bile Acids in Chronic Lymphocytic Leukemia. [PDF]

Biomedicines
Smith AL, Ridout A, Skupa SA, Martinez-Rico R, Drengler EM, Mohamed E, D'Angelo CR, El-Gamal D.   +7 more
europepmc   +1 more source

A new clustering: Angiogenesis‐associated molecular classification of lung adenocarcinoma

VIEW, EarlyView.
Lung adenocarcinoma (LUAD) is a heterogeneous disease, with varying patient prognosis and challenges in personalized treatments. We identified three LUAD subtypes based on angiogenesis‐related genes in this study, revealing distinct biological features and key survival‐related genes that could serve as targets for personalized therapies.
Lin Zhu, Li Zhu, Kai Nie, Yuxuan Zhang, Qunhui Chen, Yan Shen, Yifeng Jiang, Lingming Yu, Shaojie Li, Yanbing Sun, Qiming Ni, Jiahui Yu, Guangyu Tao, Jun Xing, John Parrington, Lin Huang, Hong Yu   +16 more
wiley   +1 more source

Characteristics and outcomes of patients with double refractory and double exposed chronic lymphocytic leukemia. [PDF]

Blood Adv
Yoon JT, Zhou Y, Mikhaleva M, Choi DS, Fernandes SM, Armand P, Bessnow AC, Crombie JL, Fisher DC, Jacobsen ED, Jacobson CA, Kim AI, LaCasce AS, Merryman RW, Odejide OO, Parry EM, Qualls DA, Ryan CE, Sekar A, Soumerai JD, Arnason J, Tyekucheva S, Davids MS, Brown JR, Ahn IE.   +24 more
europepmc   +1 more source

Fibrosarcoma on the leg of an adult rhesus macaque (Macaca mulatta)

Veterinary Record Case Reports, EarlyView.
Abstract This case describes a fibrosarcoma on the left upper leg of an adult female rhesus macaque. The patient was initially presented with a defined swelling at the caudolateral side of the upper leg. Medially from the growth, a swollen circular wound had formed with a fistula leading in the direction of the mass.
Merel Wegman, Nadiah M. H. A. van Eijk, Jaco Bakker, Judith M. A. van den Brand, Jan A. M. Langermans   +4 more
wiley   +1 more source

Chronic Lymphocytic Leukemia Infiltrating in the Brain. [PDF]

Cureus
Webb LM, Kenderian SS, Angeli AM, Howard MT, Wijdicks EF.   +4 more
europepmc   +1 more source

Maximum Standard Uptake Value of Pre‐Therapeutic 18F‐Fluorodeoxyglucose Positron Emission Tomography Predicts Outcomes in Indolent Adult T‐Cell Leukemia/Lymphoma Patients With Cutaneous Involvement

The Journal of Dermatology, EarlyView.
ABSTRACT The prognostic utility of 18F‐fluorodeoxyglucose positron emission tomography (FDG‐PET) in adult T‐cell leukemia/lymphoma (ATLL) remains unclear, particularly in patients with indolent subtypes and cutaneous involvement. This study aimed to evaluate the usefulness of FDG‐PET in predicting clinical outcomes in patients with indolent ATLL ...
Kyoko Nogami, Yotaro Nishikawa, Kosuke Mochida, Tamasa Terada, Minako Azuma, Michikazu Nakai, Masahiro Amano   +6 more
wiley   +1 more source

Greek Consensus on Chronic Lymphocytic Leukemia (CLL) Treatment. [PDF]

Mediterr J Hematol Infect Dis
Sachanas S, Vassilakopoulos T, Angelopoulou M, Papageorgiou S, Spanoudakis E, Bouzani M, Dimou M, Panagiotidis P.   +7 more
europepmc   +1 more source

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

Allergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado   +17 more
wiley   +1 more source