Results 91 to 100 of about 2,804,111 (259)

Genes and primary headaches: discovering new potential therapeutic targets [PDF]

, 2013
Genetic studies have clearly shown that primary headaches (migraine, tension-type headache and cluster headache) are multifactorial disorders characterized by a complex interaction between different genes and environmental factors.
De Martino, Paola, Gai, Annalisa, Gentile, Salvatore, Paemeleire, Koen, Pinessi, Lorenzo, Rainero, Innocenzo, Rubino, Elisa, Sarchielli, Paola, Vacca, Alessandro   +8 more
core   +3 more sources

1H-MRS reveals abnormal energy metabolism and excitatory-inhibitory imbalance in a chronic migraine-like state induced by nitroglycerin in mice

The Journal of Headache and Pain
Background Chronic migraine is closely related to the dysregulation of neurochemical substances in the brain, with metabolic imbalance being one of the proposed causes of chronic migraine.
Jinggui Gao, Da Wang, Chenlu Zhu, Jian Wang, Tianxiao Wang, Yunhao Xu, Xiao Ren, Kaibo Zhang, Cheng Peng, Jisong Guan, Yonggang Wang   +10 more
doaj   +1 more source

Familial aggregation of migraine and depression: Insights from a large Australian twin sample [PDF]

, 2016
Free to read\ud \ud Objectives: This research examined the familial aggregation of migraine, depression, and their co-occurrence.\ud \ud Methods: Diagnoses of migraine and depression were determined in a sample of 5,319 Australian twins.
Heath, Andrew C, Madden, Pamela A. F, Martin, Nicholas G, Nyholt, Dale R, Yang, Yuanhao, Zhao, Huiying   +5 more
core   +3 more sources

Episodic and chronic migraine in children

Developmental Medicine & Child Neurology, 2020
Migraine is the most common acute and recurrent headache syndrome in children. This condition has unique clinical characteristics in the pediatric population, that can evolve with age, and significantly impact a child's quality of life, affecting their ...
Paul E. Youssef, K. Mack
semanticscholar   +1 more source

From transformation to chronification of migraine: pathophysiological and clinical aspects

The Journal of Headache and Pain, 2020
Chronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features.
M. Torres-Ferrús, F. Ursitti, A. Alpuente-Ruiz, F. Brunello, D. Chiappino, T. de Vries, S. Di Marco, S. Ferlisi, L. Guerritore, N. Gonzalez-Garcia, A. Gonzalez-Martinez, D. Khutorov, M. Kritsilis, A. Kyrou, T. Makeeva, A. Minguez-Olaondo, L. Pilati, A. Serrien, O. Tsurkalenko, D. Van den Abbeele, W. S. van Hoogstraten, C. Lampl, On behalf of School of Advanced Studies of European Headache Federation (EHF-SAS)   +22 more
doaj   +1 more source

Relevance of lactate level detection in migrane and fibromyalgia [PDF]

, 2019
The aim of this study was to determine the blood lactate levels in healthy and pathological subjects, particularly with migraine and fibromyalgia. Moreover we investigated the possible correlation between lactate concentration, postural stability and ...
Amato, A, Brighina F, Brusa, J, Contrò, V, LO MONACO, Alessandra, Messina G, Proia, P   +6 more
core   +2 more sources

Efficacy of Multi-Modal Migraine Prophylaxis Therapy on Hyperacusis Patients. [PDF]

, 2020
ObjectivesTo evaluate the efficacy of a multi-modal migraine prophylaxis therapy for patients with hyperacusis.MethodsIn a prospective cohort, patients with hyperacusis were treated with a multi-modal step-wise migraine prophylactic regimen ...
Abouzari, Mehdi, Djalilian, Hamid R, Ghavami, Yaser, Goshtasbi, Khodayar, Lin, Harrison W, Parker, Erica M, Sarna, Brooke, Tan, Donald   +7 more
core  

Choosing the safest acute combination therapy during prophylactic treatment. pharmacokinetic and pharmacodynamic considerations [PDF]

, 2015
Drugs used in the treatment of migraine have been recently reported to be highly associated with the occurrence of clinically significant drug-drug interactions (DDIs)
Lionetto, Luana, MARTELLETTI, Paolo
core   +1 more source

Frequent mild head injury promotes trigeminal sensitivity concomitant with microglial proliferation, astrocytosis, and increased neuropeptide levels in the trigeminal pain system. [PDF]

, 2017
BACKGROUND: Frequent mild head injuries or concussion along with the presence of headache may contribute to the persistence of concussion symptoms. METHODS: In this study, the acute effects of recovery between mild head injuries and the frequency of ...
Assari, Soroush, Cheng, Lan, Darvish, Kurosh, Elliott, Melanie B, Tyburski, Ashley L.   +4 more
core   +2 more sources

Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease

Arquivos de Neuro-Psiquiatria
Objective To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital.
Mariana Tedeschi Benatto, Lidiane Lima Florencio, Gabriela Ferreira Carvalho, Fabíola Dach, Marcelo Eduardo Bigal, Thaís Cristina Chaves, Débora Bevilaqua-Grossi   +6 more
doaj   +1 more source