Results 61 to 70 of about 2,712,287 (341)
The white matter state in migraine has been investigated using diffusion tensor imaging (DTI) measures, but results using this technique are conflicting.
Álvaro Planchuelo-Gómez+5 more
doaj +1 more source
Impact of the botulinum-A toxin on prevention of adult migraine disorders [PDF]
A systematic review of the impact of botulinum-A toxin as a therapeutic regimen for the management of adult migraine disorders is shown to that Botulinum-A toxin provides a more significant reduction in the number of headache episodes per month relative ...
Bin Shen, Lan Wang
doaj +1 more source
BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach+11 more
wiley +1 more source
Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova+5 more
wiley +1 more source
Background Migraine is a prevalent, chronic, and multifactorial neurovascular disease. Objectives Our work aimed to investigate if the retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thickness are affected in patients with chronic migraine
Dalia M. Labib+4 more
doaj +1 more source
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox+3 more
wiley +1 more source
Patient self rated pain: headache versus migraine a retrospective chart review
Background The International Classification of Headache Disorders (ICHD-3) uses moderate or severe pain intensity in the diagnostic criterion for migraine.
Elizabeth Toigo+4 more
doaj +1 more source
Acute withdrawal of headache medication in chronic migraine patients with medication overuse may lead to a dramatic reduction in headache frequency and severity.
Veronica Mäki-Marttunen+8 more
doaj
Introduction. Preexisting chronic pain has been reported to be a consistent risk factor for severe acute postoperative pain. However, each specific chronic pain condition has unique pathophysiology, and it is possible that the effect of each condition on
Ryu Komatsu+11 more
doaj +1 more source
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho+7 more
wiley +1 more source