Results 61 to 70 of about 94,133 (343)

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Feasibility of serum CGRP measurement as a biomarker of chronic migraine: a critical reappraisal

The Journal of Headache and Pain, 2018
Background Calcitonin gene-related peptide (CGRP) has been reported as elevated in chronic migraine. We aimed to validate the role of interictal serum CGRP concentration in peripheral blood samples as a biomarker of chronic migraine.
Mi Ji Lee, Sook-Yeon Lee, Soohyun Cho, Eun-Suk Kang, Chin-Sang Chung   +4 more
doaj   +1 more source

Prophylactic treatment can modify vascular risk biomarkers in high-frequency episodic and chronic migraine patients: a pilot study

Scientific Reports, 2023
To evaluate whether preventive treatment can modify endothelial and oxidative biomarkers of vascular disease risk in patients with high-frequency episodic and chronic migraine.
Cristina González Mingot, Sonia Santos Lasaosa, Laura Colàs Campàs, Laura Chilangua Canaval, Anna Gil Sánchez, Luis Brieva Ruiz, María Cristina Marzo Alonso, Silvia Peralta Moncusi, Joan Valls Marsal, Serafí Cambray Carner, Francisco Purroy García   +10 more
doaj   +1 more source

My migraine voice survey. aA global study of disease burden among individuals with migraine for whom preventive treatments have failed [PDF]

, 2018
Background: Migraine is associated with many debilitating symptoms that affect daily functioning. My Migraine Voice is a large global cross-sectional study aimed at understanding the full burden and impact of migraine directly from patients suffering ...
Carboni, Veruska, Craven, Audrey, Diener, Hans-Christoph, Dumas, Paula, Evans, Simon, Fink, Rachel, Laflamme, Annik K., Lanteri-Minet, Michel, Martelletti, Paolo, Quintana, Rebeca, Rasmussen, Annette Vangaa, Ruiz De La Torre, Elena, Schwedt, Todd J., Vo, Pamela, Walsh, Donna   +14 more
core   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

Advanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M. Morshead, David Chatenet, Molly S. Shoichet   +7 more
wiley   +1 more source

Cathodal Occipital tDCS is unable to modulate The Sound Induced Flash Illusion in migraine [PDF]

, 2019
Migraine is a highly disabling disease characterized by recurrent pain.Despite an intensive effort, mechanisms of migraine pathophysiology, still represent an unsolved issue.
Filippo Brighina, Giuseppe Cosentino, Giuseppe Giglia, GIUSEPPE SALEMI, Massimo Gangitano, Nadia Bolognini, Simona Maccora   +6 more
core   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Patient self rated pain: headache versus migraine a retrospective chart review

Head & Face Medicine
Background The International Classification of Headache Disorders (ICHD-3) uses moderate or severe pain intensity in the diagnostic criterion for migraine.
Elizabeth Toigo, Erin Pellot, Hannah Lyons, Peter McAllister, Martin Taylor   +4 more
doaj   +1 more source

OnabotulinumtoxinA in the treatment of patients with chronic migraine: clinical evidence and experience

Therapeutic Advances in Neurological Disorders, 2017
Chronic migraine is a debilitating neurobiological disorder that affects approximately 1.4–2.2% of the population worldwide. Patients with chronic migraine have 15 or more headache days per month, with at least 8 days per month that meet the criteria for
Chia-Chun Chiang, Amaal J. Starling
doaj   +1 more source

A volumetric magnetic resonance imaging study in migraine

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Although migraine phenotype has been widely described, the explanation of migraine pathophysiology still has a gap that might be partly bridged by neuroimaging investigations.
Laila Elmously Naguib, Ghada Saed Abdel Azim, Mohammed Abdelrazek Abdellatif   +2 more
doaj   +1 more source