Results 71 to 80 of about 2,830,257 (398)
Brain Sciences, 2020 The white matter state in migraine has been investigated using diffusion tensor imaging (DTI) measures, but results using this technique are conflicting.
Álvaro Planchuelo-Gómez +5 more
doaj +1 more source
The Journal of Headache and Pain, 2020 Background PROMISE-2 was a phase 3, randomized, double-blind, placebo-controlled study that evaluated the efficacy and safety of repeat intravenous (IV) doses of the calcitonin gene-related peptide–targeted monoclonal antibody eptinezumab (ALD403) for ...
S. Silberstein +9 more
semanticscholar +1 more source
Comorbid pain and migraine chronicity [PDF]
Neurology, 2017 To identify patterns of noncephalic pain comorbidity in people with episodic migraine (EM;
Scher, Ann I. +6 more
openaire +2 more sources
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Advanced Science, EarlyView.Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
Therapeutic Advances in Neurological Disorders, 2017 Chronic migraine is a debilitating neurobiological disorder that affects approximately 1.4–2.2% of the population worldwide. Patients with chronic migraine have 15 or more headache days per month, with at least 8 days per month that meet the criteria for
Chia-Chun Chiang, Amaal J. Starling
doaj +1 more source
Feasibility of serum CGRP measurement as a biomarker of chronic migraine: a critical reappraisal
The Journal of Headache and Pain, 2018 Background Calcitonin gene-related peptide (CGRP) has been reported as elevated in chronic migraine. We aimed to validate the role of interictal serum CGRP concentration in peripheral blood samples as a biomarker of chronic migraine.
Mi Ji Lee +4 more
doaj +1 more source
A volumetric magnetic resonance imaging study in migraine
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021 Background Although migraine phenotype has been widely described, the explanation of migraine pathophysiology still has a gap that might be partly bridged by neuroimaging investigations.
Laila Elmously Naguib +2 more
doaj +1 more source
A hypothetical proposal for association between migraine and Meniere's disease. [PDF]
, 2020 Meniere's disease (MD) is a chronic condition affecting the inner ear whose precise etiology is currently unknown. We propose the hypothesis that MD is a migraine-related phenomenon which may have implications for future treatment options for both ...
Abouzari, Mehdi +3 more
core
Update on medication-overuse headache and its treatment [PDF]
, 2015 OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA +2 more
core +1 more source
Headache, 2021 Chronic overlapping pain conditions (COPCs) represent a co‐aggregation of widespread pain disorders. We characterized differences in physical and psychosocial functioning in patients with chronic migraine (CM) and those with CM and COPCs.
M. Barad +4 more
semanticscholar +1 more source