Advanced Science, EarlyView.Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei +10 more
wiley +1 more source
Editorial: Hematopoietic Stem Cell Theory in Relation to Possible Lymphoblastic Conversion of Chronic Myeloid Leukemia [PDF]
, 1974 Dane R. Boggs
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Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy
Aggregate, EarlyView.Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang +6 more
wiley +1 more source
Granulopoiesis in chronic myeloid leukemia. II. serial cloning of blood and bone marrow cells in agar culture [PDF]
, 1976 T Olofsson, Inge Olsson
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Impact of Cytogenetic Response to Therapy on Long‐Term Survival in Acute Myeloid Leukemia
American Journal of Hematology, EarlyView.ABSTRACT Prognostication in acute myeloid leukemia (AML) relies on clinical, molecular, and cytogenetic factors. In this retrospective study, we examined the impact of different levels of cytogenetic response on overall survival (OS) and event‐free survival (EFS) in AML.
John Hanna +22 more
wiley +1 more source
Chronic myeloid leukemia: past, present, future [PDF]
Einstein (São Paulo), 2011 The discovery of the Philadelphia chromosome in 1960, and of theBCR-ABL oncogene in 1984, enabled the development in subsequentyears of a targeted therapy that revolutionized the treatment of chronic myeloid leukemia, thus changing its natural history ...
Patricia Weinschenker Bollmann +1 more
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Spontaneous leukocyte oscillation during blastic crisis of chronic myeloid leukemia [PDF]
, 1974 Renato Mastrangelo +3 more
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Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects
Animal Models and Experimental Medicine, EarlyView.This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang +5 more
wiley +1 more source
Treatment of juvenile chronic myeloid leukemia with sequential subcutaneous cytarabine and oral mercaptopurine [PDF]
, 1977 JS Lilleyman, JF Harrison, JA Black
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Advanced NanoBiomed Research, EarlyView.Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo +2 more
wiley +1 more source