Results 71 to 80 of about 2,297,875 (300)

Deterioration of Respiratory Symptoms in Uncontrolled CPFE: A Case Report

Jurnal Respirasi
Introduction: Chronic obstructive pulmonary disease (COPD) has a global impact on health and increases healthcare costs. Combined pulmonary fibrosis and emphysema (CPFE) combines interstitial lung disease (ILD) and emphysema.
Frans Raffael, Amira Permatasari Tarigan
doaj   +1 more source

Angiogenesis in Chronic Obstructive Pulmonary Disease [PDF]

, 2012
Angiogenesis is a crucial component of lung pathophysiology, not only in cancer but also in other disorders, such as chronic obstructive pulmonary disease (COPD).
Gaetano Santulli, Alessandro Matarese
core  

Impaired Postural Control Reduces Sit-to-Stand-to-Sit Performance in Individuals with Chronic Obstructive Pulmonary Disease [PDF]

, 2014
Background: Functional activities, such as the sit-to-stand-to-sit (STSTS) task, are often impaired in individuals with chronic obstructive pulmonary disease (COPD).
Janssens, L, Burtin, C., Alison K McConnell, Goossens, N., Janssens Lotte, Marc Decramer, McConnell Alison K., Lotte Janssens, Burtin, Chris, Claeys Kurt, Janssens, W, Simon Brumagne, Janssens, Wim, McConnell, AK, Janssens, L., Wim Janssens, Troosters, T, Brumagne, S., McConnell, Alison K., Brumagne Simon, Decramer, Marc, Burtin, C, Pijnenburg, M., Troosters Thierry, Pijnenburg Madelon, Goossens, Nina, Nina Goossens, Chris Burtin, Decramer, M., Goossens, N, Kurt Claeys, Brumagne, S, Pijnenburg, M, Claeys, K., Troosters, T., Decramer Marc, Brumagne, Simon, Madelon Pijnenburg, Claeys, Kurt, Pijnenburg, Madelon, Decramer, M, Goossens Nina, Janssens Wim, Claeys, K, Thierry Troosters, Janssens, W., Troosters, Thierry, Janssens, Lotte, Burtin Chris   +48 more
core   +2 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Chronic insomnia remitting after maxillomandibular advancement for mild obstructive sleep apnea: a case series

Journal of Medical Case Reports, 2019
Background Chronic insomnia and obstructive sleep apnea are both common sleep disorders. Chronic insomnia is thought to result from stress-related physiologic hyperarousal (somatic arousal) that makes it difficult for an individual to fall or stay asleep.
Michael Proothi, Victor J. R. Grazina, Avram R. Gold   +2 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

High urinary desmosine is associated with long-term mortality in patients with COPD

ERJ Open Research, 2023
Changhwan Kim, Yousang Ko, Jae Seung Lee, Chin Kook Rhee, Jin Hwa Lee, Ji-Yong Moon, Seong Yong Lim, Kwang Ha Yoo, Joon Beom Seo, Yeon-Mok Oh, Sang-Do Lee, Yong Bum Park   +11 more
doaj   +1 more source

Gut microbiota-ferroptosis signaling as a putative feed-forward amplifier of pulmonary immunometabolic reprogramming in acute respiratory distress syndrome: actionable therapeutic targets

Frontiers in Immunology
Acute respiratory distress syndrome (ARDS) is characterized by dysregulated pulmonary immune responses, and effective targeted therapeutic strategies remain an unmet clinical need.
Biying Dong, Biying Dong, Biying Dong, Biying Dong, Weitong Zeng, Weitong Zeng, Bing Zhong, Bing Zhong, Longxiong Liao, Longxiong Liao, Longxiong Liao, Longxiong Liao, Yi Wei, Yi Wei, Lihua Liao, Dongwei Zhang, Dongwei Zhang, Xianming Fan, Xianming Fan   +18 more
doaj   +1 more source

Call to action: improving primary care for women with COPD

npj Primary Care Respiratory Medicine, 2017
In this perspective-based article, which is based on findings from a comprehensive literature search, we discuss the significant and growing burden of chronic obstructive pulmonary disease in women worldwide.
Ioanna Tsiligianni, Miguel Román Rodríguez, Karin Lisspers, Tze LeeTan, Antonio Infantino   +4 more
doaj   +1 more source