The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Estimating the cost-effectiveness of fluticasone propionate for treating chronic obstructive pulmonary disease in the presence of missing data [PDF]
Objectives: To explore the cost-effectiveness of fluticasone propionate (FP) for the treatment of chronic obstructive pulmonary disease (COPD), we estimated costs and qualityadjusted life-years (QALYs) over 3 years, based on an economic appraisal of a ...
Spencer, Michael D. +22 more
core +1 more source
The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci +25 more
wiley +1 more source
Angiogenesis in Chronic Obstructive Pulmonary Disease [PDF]
Angiogenesis is a crucial component of lung pathophysiology, not only in cancer but also in other disorders, such as chronic obstructive pulmonary disease (COPD).
Gaetano Santulli, Alessandro Matarese
core
Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram +25 more
wiley +1 more source
Comparative Study on the Quality of Life of Chronic Obstructive Pulmonary Disease Patients [PDF]
Objective: The main goal of this study is to compare the Quality of Life (QoL) of Chronic Obstructive Pulmonary Disease (COPD) patients between three different regions: the United Arab Emirates (UAE), the United Kingdom (UK) and Morocco. Another aim of
Bihi, Imane Ben
core +3 more sources
Biologics and chronic obstructive pulmonary disease [PDF]
The presence of airway inflammation in patients with chronic obstructive pulmonary disease (COPD) provides a rationale for biological agents targeting specific inflammatory pathways. This approach has been strikingly effective in patients with other chronic inflammatory diseases, such as rheumatoid arthritis, psoriasis, and asthma.
openaire +2 more sources
Systematic review on inhaled corticosteroid monotherapy and its efficacy and safety in longterm treatment of patients with chronic obstructive pulmonary disease (COPD) [PDF]
--chronic obstructive pulmonary disease,COPD,corticosteroids,systematic review,chronisch obstruktive Lungenerkrankung,COPD,Kortikosteroid,systematischer ...
Wasem, Jürgen +4 more
core
Breathing and Breathlessness: Chronic Obstructive Pulmonary Disease in Uruguay [PDF]
An increasingly common part of being human is living with chronic health problems for which management over time, and not cure, is the goal of medical treatment.
Wainwright, M., WAINWRIGHT, MEGAN,JULIE
core
Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo +6 more
wiley +1 more source

