Results 101 to 110 of about 781,661 (389)

Comorbidities of patients in tiotropium clinical trials : comparison with observational studies of patients with chronic obstructive pulmonary disease [PDF]

, 2015
Acknowledgments The authors are fully responsible for all content and editorial decisions made, were involved at all stages of manuscript development, and have approved the final version for publication.
Celli, Bartolome, Metzdorf, Norbert, Miravitlles, Marc, Price, David, Rabe, Klaus F, Schmidt, Hendrik   +5 more
core   +1 more source

Machine learning reveals sex differences in clinical features of acute exacerbation of chronic obstructive pulmonary disease: A multicenter cross-sectional study [PDF]

, 2023
Zhi Hong Chen, Jiajia Wang, Hanchao Wang, Yu Yao, Huojin Deng, Junnan Peng, Xinglong Li, Zhongruo Wang, Xingru Chen, Wei Xiong, Qin Wang, Tao Zhu   +11 more
openalex   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Biologics and chronic obstructive pulmonary disease [PDF]

Journal of Allergy and Clinical Immunology, 2018
The presence of airway inflammation in patients with chronic obstructive pulmonary disease (COPD) provides a rationale for biological agents targeting specific inflammatory pathways. This approach has been strikingly effective in patients with other chronic inflammatory diseases, such as rheumatoid arthritis, psoriasis, and asthma.
openaire   +2 more sources

Systematic review on inhaled corticosteroid monotherapy and its efficacy and safety in longterm treatment of patients with chronic obstructive pulmonary disease (COPD) [PDF]

--chronic obstructive pulmonary disease,COPD,corticosteroids,systematic review,chronisch obstruktive Lungenerkrankung,COPD,Kortikosteroid,systematischer ...
Buchberger, Barbara, Kossmann, Beate, Neumann, Anja, Niebuhr, Dea, Wasem, Jürgen   +4 more
core  

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD : current evidence and future prospects [PDF]

, 2019
Long-acting bronchodilators are the cornerstone of pharmacologic treatment of chronic obstructive pulmonary disease (COPD). Spiolto (R) or Stiolto (R) is a fixed-dose combination (FDC) containing two long-acting bronchodilators, the long-acting ...
Brusselle, Guy, Derom, Eric, Joos, Guy
core   +1 more source

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell type and phenotype associations

Nature Genetics, 2019
Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed a genome-wide association study in 35,735 cases and 222,076 controls from
P. Sakornsakolpat, Dmitry Prokopenko, M. Lamontagne, N. Reeve, A. Guyatt, V. Jackson, N. Shrine, D. Qiao, T. Bartz, D. Kim, Mi Kyeong Lee, J. Latourelle, Xingnan Li, J. Morrow, M. Obeidat, A. Wyss, P. Bakke, R. Barr, T. Beaty, S. Belinsky, G. Brusselle, J. Crapo, K. Jong, D. Demeo, T. Fingerlin, S. Gharib, A. Gulsvik, I. Hall, J. Hokanson, W. Kim, D. Lomas, S. London, D. Meyers, G. O'Connor, S. Rennard, D. Schwartz, P. Śliwiński, D. Sparrow, D. Strachan, R. Tal-Singer, Y. Tesfaigzi, J. Vestbo, J. Vonk, J. Yim, Xiaobo Zhou, Y. Bossé, A. Manichaikul, L. Lahousse, E. Silverman, H. Boezen, L. Wain, M. Tobin, B. Hobbs, M. Cho, C. Batini, Jinghua Zhao, M. Wielscher, S. Weiss, K. Kentistou, J. Cook, J. Hui, S. Karrasch, M. Imboden, S. Harris, J. Marten, Stefan Enroth, S. Kerr, I. Surakka, V. Vitart, T. Lehtimäki, R. Ewert, C. Gieger, G. Homuth, Peter K. Joshi, C. Langenberg, L. Lind, J. Luan, A. Mahajan, Alison D. Murray, D. Porteous, R. Rawal, Blair H. Smith, P. Timmers, O. Raitakari, M. Kähönen, O. Polašek, U. Gyllensten, I. Rudan, I. Deary, N. Probst-Hensch, H. Schulz, A. James, James F. Wilson, B. Stubbe, E. Zeggini, M. Jarvelin, N. Wareham, C. Hayward, Andrew P Morris, A. Agustí, W. Anderson, N. Bakerly, R. Bals, Kathleen C. Barnes, E. Bleecker, Russell P Bowler, C. Brightling, Marleen de Bruijne, P. Castaldi, B. Celli, H. Coxson, R. Crystal, P. D. Jong, A. Dirksen, J. Dy, M. Foreman, J. Garcia-Aymerich, P. Gevenois, Soumitra Ghosh, H. Gietema, N. Hansel, C. Hersh, E. Hoffman, N. Kalsheker, H. Kauczor, Tarja Laitinen, D. Lambrechts, Sang-Do Lee, A. Litonjua, D. Loth, S. Lutz, D. Lynch, W. Macnee, Merry-Lynn N. McDonald, J. Newell, B. Nordestgaard, Y. Oh, P. Paré, M. Pistolesi, D. Postma, M. Puhan, E. Regan, S. Rich, J. Seo, Andrea B. Short, B. Stoel, N. Sverzellati, G. Riet, E. V. Beek, B. Ginneken, C. Vogelmeier, A. Wanner, G. Washko, E. Wauters, E. Wouters, R. P. Young, L. Zeigler-Heitbrock   +156 more
semanticscholar   +1 more source

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD [PDF]

, 2014
Dirkje S Postma,1 Nicolas Roche,2 Gene Colice,3 Elliot Israel,4 Richard J Martin,5 Willem MC van Aalderen,6 Jonathan Grigg,7 Anne Burden,8 Elizabeth V Hillyer,8 Julie von Ziegenweidt,8 Gokul Gopalan,9 David Price8,10 1University of Groningen, Department ...
Burden, A, Colice, G, Gopalan, G, Grigg, J, Hillyer, EV, Israel, E, Martin, RJ, Postma, DS, Price, D, Roche, N, van Aalderen, WMC, von Ziegenweidt, J   +11 more
core   +6 more sources

COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease.

Chronic obstructive pulmonary diseases, 2019
Background Chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity and mortality. Present-day diagnostic criteria are largely based solely on spirometric criteria.
Katherine E. Lowe, E. Regan, A. Anzueto, E. Austin, J. Austin, T. Beaty, P. Benos, Christopher J Benway, S. Bhatt, E. Bleecker, Sandeep Bodduluri, J. Bon, A. Boriek, A. Boueiz, R. Bowler, M. Budoff, R. Casaburi, P. Castaldi, J. Charbonnier, M. Cho, A. Comellas, D. Conrad, Corinne Costa Davis, G. Criner, D. Curran-Everett, J. Curtis, D. Demeo, A. Díaz, M. Dransfield, Jennifer G. Dy, A. Fawzy, M. Fleming, E. Flenaugh, M. Foreman, Spyridon Fortis, H. Gebrekristos, S. Grant, P. Grenier, T. Gu, Abhya Gupta, M. Han, N. Hanania, N. Hansel, L. Hayden, C. Hersh, B. Hobbs, E. Hoffman, J. Hogg, J. Hokanson, K. Hoth, A. Hsiao, S. Humphries, K. Jacobs, F. Jacobson, E. Kazerooni, V. Kim, W. Kim, G. Kinney, H. Koegler, S. Lutz, D. Lynch, Neil R MacIntye, B. Make, N. Marchetti, F. Martinez, D. Maselli, A. Mathews, M. McCormack, Merry-Lynn N. McDonald, C. Mcevoy, M. Moll, Sarah S Molye, S. Murray, H. Nath, J. Newell, M. Occhipinti, M. Paoletti, T. Parekh, M. Pistolesi, K. Pratte, N. Putcha, M. Ragland, J. Reinhardt, S. Rennard, R. Rosiello, J. Ross, H. Rossiter, I. Ruczinski, Raúl San José Estépar, F. Sciurba, J. Sieren, Harjinder Singh, Xavier Soler, R. Steiner, M. Strand, W. Stringer, R. Tal-Singer, B. Thomashow, Gonzalo Vegas Sánchez-Ferrero, J. Walsh, E. Wan, G. Washko, J. Michael Wells, C. Wendt, G. Westney, A. Wilson, R. Wise, A. Yen, K. Young, J. Yun, E. Silverman, J. Crapo   +111 more
semanticscholar   +1 more source