Results 71 to 80 of about 330,247 (298)

Investigating fibrinogen levels as a biomarker for immune inflammation severity in COPD patients across GOLD stages

open access: yesJournal of the Pakistan Medical Association
Objective: To assess the association between fibrinogen levels and immune inflammation severity in patients with chronic obstructive pulmonary disease at different stages of the Global Initiative for Chronic Obstructive Lung Disease classification ...
Hamidullah   +4 more
doaj   +1 more source

Features and patterns of expression of lectin receptors in the lungs of patients with chronic obstructive pulmonary disease exacerbation and remission [PDF]

open access: yesМорфологія, 2013
Background. Chronic obstructive pulmonary disease is a widespread pathology, and the problem of its diagnostics is still of current interest. Objective. To determine the principles of lectin receptors expression and distribution in patients with chronic ...
Malofiy L.S.
doaj  

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

open access: yesAdvanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song   +9 more
wiley   +1 more source

Association between left ventricular diastolic dysfunction and severity of chronic obstructive pulmonary disease

open access: yesClinics, 2013
OBJECTIVES: The prevalence of electrocardiographic and echocardiographic abnormalities in chronic obstructive pulmonary disease according to disease severity has not yet been established.
Laura Miranda de Oliveira Caram   +7 more
doaj  

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang   +13 more
wiley   +1 more source

Association between Psoriasis and Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis.

open access: yesPLoS ONE, 2015
Psoriasis is considered a systemic inflammatory disorder. Previous studies have reported conflicting positive or negative correlations between psoriasis and chronic obstructive pulmonary disease. We performed a meta-analysis to determine whether there is
Xin Li   +8 more
doaj   +1 more source

Microbiological features of bronchial asthma and chronic obstructive pulmonary disease during remission

open access: yesКлиническая практика, 2018
Background: Bronchial asthma and chronic obstructive pulmonary disease are currently the fifth leading cause of death in the world. The combination of bronchial asthma and chronic obstructive pulmonary disease seems to be a unique disease resulting from ...
M. Yu. Smirnova-Saprytskaya   +4 more
doaj   +1 more source

Hemodynamic Effects of Aminophylline in Chronic Obstructive Pulmonary Disease [PDF]

open access: bronze, 1967
John O. Parker   +3 more
openalex   +1 more source

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

open access: yesAdvanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo   +16 more
wiley   +1 more source

Asthma and chronic obstructive pulmonary disease overlap: asthmatic chronic obstructive pulmonary disease or chronic obstructive asthma?

open access: yesTherapeutic Advances in Respiratory Disease, 2016
Asthma and chronic obstructive pulmonary disease (COPD) are different disease entities. They are both clinical diagnoses, with diagnostic tools to discriminate between one another. However, especially in older patients (>55 years) it seems more difficult
Annelies Slats, Christian Taube
doaj   +1 more source

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