Results 21 to 30 of about 1,647,688 (179)

TRPM8 Agonist (Cryosim-1) Cream for Chronic Prurigo: A Randomized, Vehicle-controlled Trial [PDF]

open access: yesActa Dermato-Venereologica
Chronic prurigo (CP) is a distressing dermatological condition lacking effective topical therapies. This randomized, double-blind, vehicle-controlled trial evaluated the efficacy and safety of Cryosim-1, a TRPM8 agonist cream, in 30 adults with CP ...
Ji Young Um   +5 more
doaj   +2 more sources

Thalidomide for the treatment of chronic refractory prurigo nodularis [PDF]

open access: yesDermatology Online Journal, 2018
Prurigo nodularis (PN) is a highly pruritic skin condition that is caused by chronic scratching. It occurs in patients with chronic itch and is characterized by multiple hyperkeratotic papules and nodules. The pathogenesis of PN is unclear, but involves a complex interplay of numerous pathways including neurogenic and inflammatory factors.
Aguh, Crystal   +3 more
openaire   +6 more sources

Biopsychosocial factors associated with prurigo nodularis in endogenous eczema

open access: yesIndian Journal of Dermatology, 2015
Background: Prurigo nodularis is a dermatological manifestation secondary to chronic scratching or picking on focal areas of the skin. Its pathogenesis remains poorly understood, and limited data has indicated its association with psychological factors ...
Choon Chiat Oh   +3 more
doaj   +2 more sources

Prurigo: review of its pathogenesis, diagnosis, and treatment [PDF]

open access: yesAnais Brasileiros de Dermatologia
Prurigo is a reactive, hyperplastic skin condition characterized by pruritic papules, plaques, and/or nodules. The temporal classification includes acute/subacute and chronic disease (≥ 6 weeks), with different clinical variants, synonymies, and ...
Paulo Ricardo Criado   +5 more
doaj   +2 more sources

Aprepitant in Anti-histamine-refractory Chronic Nodular Prurigo: A Multicentre, Randomized, Double-blind, Placebo-controlled, Cross-over, Phase-II trial (APREPRU)

open access: yesActa Dermato-Venereologica, 2019
The aim of this multicentre, randomized, double-blind, placebo-controlled, cross-over, phase-II study was to determine the antipruritic effect of aprepitant vs.
Athanasios Tsianakas   +12 more
doaj   +2 more sources

Treatment-resistant prurigo nodularis: challenges and solutions

open access: yesClinical, Cosmetic and Investigational Dermatology, 2019
Eric H Kowalski,1 Diana Kneiber,1 Manuel Valdebran,2 Umangi Patel,1 Kyle T Amber1 1Department of Dermatology, University of Illinois at Chicago, Chicago, IL, USA; 2Department of Dermatology, University of California, Irvine, Irvine, CA, USA Abstract ...
Kowalski EH   +4 more
doaj   +1 more source

Recent advances in treatment of prurigo nodularis

open access: yesDermatologica Sinica
Prurigo nodularis is a chronic skin condition which has significant negative impacts on the psychosocial function and quality of life of affected patients.
Chieh-Hsun Chen, Stephen Chu-Sung Hu
doaj   +2 more sources

Chronic Prurigo: Current Knowledge, Treatment Strategies, Future Perspectives, and Unmet Needs [PDF]

open access: yesActa Dermato-Venereologica
Ignasi Figueras   +2 more
doaj   +2 more sources

Impact of Chronic Kidney Disease Severity on the Risk of Prurigo Nodularis: A Population-Based Cohort Study

open access: yesActa Dermato-Venereologica, 2022
While dialysis is linked with prurigo nodularis, little is known about the impact of non-dialysis chronic kidney disease on prurigo nodularis. The influence of chronic kidney disease on development of prurigo nodularis was measured using the Korean ...
Hei Sung Kim   +2 more
doaj   +1 more source

The State of the Art in Chronic Prurigo Nodularis. [PDF]

open access: yesDermatol Ther (Heidelb)
Serra-Baldrich E   +6 more
europepmc   +2 more sources

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