Results 91 to 100 of about 24,978 (221)

Severe Hypoxia Reduces Adenylyl Cyclase 6 Expression and Function in Bronchial Epithelial Cells

FASEB BioAdvances, Volume 8, Issue 4, April 2026.
Adenylyl cyclase 6 (AC6) plays an important role in the generation of cyclic adenosine monophosphate (cAMP) in the lungs. In cystic fibrosis, excessive mucus production and reduced mucociliary clearance create regions of severe hypoxia that can affect cell functions.
Ryan H. Cunnington, Nisha Singh, Marziyeh Shafizadeh, John W. Hanrahan, Shyamala Dakshinamurti, Prashen Chelikani   +5 more
wiley   +1 more source

Immunogenetic profiling to predict risk of invasive fungal diseases : where are we now? [PDF]

, 2011
Invasive fungal diseases remain nowadays life-threatening conditions affecting multiple clinical settings. The onset of these diseases is dependent on numerous factors, of which the "immunocompromised" phenotype of the patients is the more often ...
Aversa, Franco, Bistoni, Giovanni, Carvalho, Agostinho, Casagrande, Andrea, Cunha, Cristina, Rodrigues, Fernando José dos Santos, Romani, Luigina   +6 more
core   +1 more source

Late-onset isavuconazole-induced liver injury

Medical Mycology Case Reports, 2018
Antifungal agents account for approximately 3% of Drug-Induced Liver Injury (DILI) cases. Isavuconazole is a novel triazole, and experience with long-term use of it is lacking.
Felix Bongomin, Isabel Rodriguez-Goncer, Carol Lorden, Akaninyene Otu, Rohit Bazaz   +4 more
doaj   +1 more source

Інвазивний легеневий аспергільоз: сучасний стан проблеми та клінічний випадок [PDF]

, 2018
Грибы рода Aspergillus продолжают оставаться важной причиной жизнеугрожающих инфекций для пациентов с нарушениями иммунитета. В статье приведен клинический случай инвазивного легочного аспергиллеза у пациента с острой миелоидной лейкемией ...
Гашинова, К.Ю., Гуртовий, В.А., Дмитриченко, В.В., Каплан, П.Ю., Колісник, Н.С., Кужевський, І.В., Мізіна, В.М.   +6 more
core   +1 more source

Chronic cavitary pulmonary aspergillosis [PDF]

International Journal of Case Reports and Images, 2018
Aspergilloma is a fungus ball composed of hyphae, fibrin, mucus, and cellular debris found within a pulmonary cavity.The pre-existing cavities are secondary to tuberculosis,sarcoidosis, bronchial cysts, bullae, ankylosing spondylitis, neoplasm and pulmonary infarction.
openaire   +1 more source

Clinical Features and Predictive Risk Factors for Prognosis in Invasive Pulmonary Aspergillosis and Pulmonary Mucormycosis

The Clinical Respiratory Journal, Volume 20, Issue 4, April 2026.
PM patients exhibit distinctions from IPA in certain clinical characteristics, laboratory parameters, and chest radiology findings. Nevertheless, both PM and IPA patients experienced higher 30‐day mortality and ICU utilization. The combination of NLR and HbA1c with existing disease assessment tools proves effective in prognosticating the disease ...
Yu Bai, Ming Wei, Jun Liu, Xi Chen, Li Gu, Yinqun Guo   +5 more
wiley   +1 more source

Stage-specific manifestation of mold infections in bone marrow transplant recipients: Risk factors and clinical significance of positive concentrated smears [PDF]

, 1997
Potassium hydroxide-concentrated smears, prepared from sedimented remains of clinical specimens, were used to distinguish between mold infection and exogenous contamination in fungal culture-positive specimens.
Chan, TK, Chen, FFE, Chiu, EKW, Ho P, L, Ip, MSM, Liang, RHS, Siau, H, Woo, PCY, Yuen, KY   +8 more
core   +1 more source

Chronic Necrotizing Pulmonary Aspergillosis

Medicine, 1982
We conclude that chronic necrotizing pulmonary aspergillosis is a clinical entity which has not usually been recognized as one of the forms of pulmonary disease due to Aspergillus species. Patients are middle-aged, and often have some evidence of impairment of host defenses such as diabetes mellitus, a connective tissue disorder, poor nutrition ...
R E, Binder, L J, Faling, R D, Pugatch, C, Mahasaen, G L, Snider   +4 more
openaire   +2 more sources

Pulmonary nodules in chronic nonbacterial osteomyelitis—the importance of considering histoplasmosis in endemic regions: comment on the article by Hospach et al

ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Leonardo Rodrigues Campos, Luiz Fernando Brüzzi Porto, Fernanda Niskier Cukier, Geraldo do Prado Juca Filho, Flavia Martins Costa, Flavio Roberto Sztajnbok, Adriana Rodrigues Fonseca   +6 more
wiley   +1 more source

Cor pulmonale complicating chronic pulmonary aspergillosis with fatal consequences: Experience from Uganda

Medical Mycology Case Reports, 2019
Cor pulmonale is a rare complication of pulmonary aspergillosis (CPA). A 45-year-old Ugandan male with a history of recurrent community-acquired pneumonias was admitted with symptoms of progressive difficulty in breathing, chronic productive cough, non ...
Felix Bongomin, Richard Kwizera, Angella Atukunda, Bruce J. Kirenga   +3 more
doaj   +1 more source