Long-term CMV monitoring and chronic rejection in renal transplant recipients [PDF]
IntroductionCytomegalovirus (CMV) is well established to be an independent risk factor for graft loss after kidney transplantation (KTx). Monitoring for CMV in the chronic phase is not defined in the current guideline.
Shoko Ishikawa +7 more
doaj +2 more sources
Defining chronic rejection in vascularized composite allotransplantation—The American Society of Reconstructive Transplantation and International Society of Vascularized Composite Allotransplantation chronic rejection working group: 2018 American Society of Reconstructive Transplantation meeting report and white paper Research goals in defining chronic rejection in vascularized composite allotransplantation [PDF]
Objectives: This report summarizes a collaborative effort between the American Society of Reconstructive Transplantation and the International Society of Vascularized Composite Allotransplantation to establish what is known about chronic rejection in ...
Christina L Kaufman +11 more
doaj +2 more sources
A chronic rejection model and potential biomarkers for vascularized composite allotransplantation. [PDF]
BackgroundChronic rejection remains the Achilles heel in vascularized composite allotransplantation. Animal models to specifically study chronic rejection in vascularized composite allotransplantation do not exist so far.
Flemming Puscz +7 more
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Chronic rejection models for vascularized composite tissue allotransplantation [PDF]
Vascularized composite tissue allotransplantation (VCA) has transformed patients’ lives by enabling limb, face, abdominal wall, and penile transplants.
Daniel T. Fisher +11 more
doaj +2 more sources
Macrophages in Chronic Rejection: The Shapeshifters Behind Transplant Survival [PDF]
Background: Organ transplant offers patients a second chance at life, yet chronic rejection remains a formidable barrier to long-term success. Unlike the instantaneous storm of acute rejection, chronic rejection is a slow, unremitting process that ...
Ahmed Uosef +2 more
doaj +2 more sources
Activation and Regulation of Indirect Alloresponses in Transplanted Patients With Donor Specific Antibodies and Chronic Rejection [PDF]
Following transplantation, human CD4+T cells can respond to alloantigen using three distinct pathways. Direct and semi-direct responses are considered potent, but brief, so contribute mostly to acute rejection.
Sumoyee Basu +11 more
doaj +2 more sources
Lymphatic Reconstruction in Kidney Allograft Aggravates Chronic Rejection by Promoting Alloantigen Presentation [PDF]
Chronic rejection of the renal allograft remains a major cause of graft loss. Here, we demonstrated that the remodeling of lymphatic vessels (LVs) after their broken during transplantation contributes to the antigen presenting and lymph nodes activating.
Jinwen Lin +7 more
doaj +2 more sources
Chronic rejection of transplanted organs remains an unresolved issue in clinical organ transplantation. The macrophages play a crucial role in the development of chronic rejection.
Wei Chen +4 more
doaj +2 more sources
The nature of chronic rejection after lung transplantation: a murine orthotopic lung transplant study [PDF]
IntroductionChronic rejection is a major complication post-transplantation. Within lung transplantation, chronic rejection was considered as airway centred. Chronic Lung Allograft Dysfunction (CLAD), defined to cover all late chronic complications, makes
Tobias Heigl +42 more
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Prevention of Chronic Rejection of Marginal Kidney Graft by Using a Hydrogen Gas-Containing Preservation Solution and Adequate Immunosuppression in a Miniature Pig Model [PDF]
In clinical kidney transplantation, the marginal kidney donors are known to develop chronic allograft rejection more frequently than living kidney donors.
Kotaro Nishi +6 more
doaj +2 more sources

