The common rejection module in chronic rejection post lung transplantation. [PDF]
PLoS ONE, 2018 RATIONALE:Recent studies suggest that similar injury mechanisms are in place across different solid organ transplants, resulting in the identification of a common rejection module (CRM), consisting of 11 genes that are overexpressed during acute and, to ...
Annelore Sacreas +9 more
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Therapies for Chronic Allograft Rejection [PDF]
Frontiers in Pharmacology, 2021 Remarkable advances have been made in the pathophysiology, diagnosis, and treatment of antibody-mediated rejection (ABMR) over the past decades, leading to improved graft outcomes.
Min Young Kim, Daniel C. Brennan
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Prevention of Chronic Rejection of Marginal Kidney Graft by Using a Hydrogen Gas-Containing Preservation Solution and Adequate Immunosuppression in a Miniature Pig Model [PDF]
Frontiers in Immunology, 2021 In clinical kidney transplantation, the marginal kidney donors are known to develop chronic allograft rejection more frequently than living kidney donors.
Kotaro Nishi +6 more
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Long-term CMV monitoring and chronic rejection in renal transplant recipients [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 IntroductionCytomegalovirus (CMV) is well established to be an independent risk factor for graft loss after kidney transplantation (KTx). Monitoring for CMV in the chronic phase is not defined in the current guideline.
Shoko Ishikawa +7 more
doaj +2 more sources
Graft IL-33 regulates infiltrating macrophages to protect against chronic rejection. [PDF]
J Clin Invest, 2020 Alarmins, sequestered self-molecules containing damage-associated molecular patterns, are released during tissue injury to drive innate immune cell pro-inflammatory responses.
Li T +22 more
europepmc +2 more sources
Chronic rejection of human face allografts. [PDF]
Am J Transplant, 2019 Face vascularized composite allografts (FVCAs) have helped patients with severe facial disfigurement, with acute rejection now largely controlled through iatrogenic immunosuppression.
Krezdorn N +11 more
europepmc +2 more sources
Clinics, 2016 OBJECTIVE: Chronic rejection remains a major cause of graft failure with indication for re-transplantation. The incidence of chronic rejection remains high in the pediatric population.
Ana Cristina Aoun Tannuri +4 more
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Defining chronic rejection in vascularized composite allotransplantation—The American Society of Reconstructive Transplantation and International Society of Vascularized Composite Allotransplantation chronic rejection working group: 2018 American Society of Reconstructive Transplantation meeting report and white paper Research goals in defining chronic rejection in vascularized composite allotransplantation [PDF]
SAGE Open Medicine, 2020 Objectives: This report summarizes a collaborative effort between the American Society of Reconstructive Transplantation and the International Society of Vascularized Composite Allotransplantation to establish what is known about chronic rejection in ...
Christina L Kaufman +11 more
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A chronic rejection model and potential biomarkers for vascularized composite allotransplantation. [PDF]
PLoS ONE, 2020 BackgroundChronic rejection remains the Achilles heel in vascularized composite allotransplantation. Animal models to specifically study chronic rejection in vascularized composite allotransplantation do not exist so far.
Flemming Puscz +7 more
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Activation and Regulation of Indirect Alloresponses in Transplanted Patients With Donor Specific Antibodies and Chronic Rejection [PDF]
Transplant InternationalFollowing transplantation, human CD4+T cells can respond to alloantigen using three distinct pathways. Direct and semi-direct responses are considered potent, but brief, so contribute mostly to acute rejection.
Sumoyee Basu +11 more
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