The common rejection module in chronic rejection post lung transplantation. [PDF]
PLoS ONE, 2018 RATIONALE:Recent studies suggest that similar injury mechanisms are in place across different solid organ transplants, resulting in the identification of a common rejection module (CRM), consisting of 11 genes that are overexpressed during acute and, to ...
Annelore Sacreas +9 more
doaj +7 more sources
Long-term CMV monitoring and chronic rejection in renal transplant recipients [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 IntroductionCytomegalovirus (CMV) is well established to be an independent risk factor for graft loss after kidney transplantation (KTx). Monitoring for CMV in the chronic phase is not defined in the current guideline.
Shoko Ishikawa +7 more
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Defining chronic rejection in vascularized composite allotransplantation—The American Society of Reconstructive Transplantation and International Society of Vascularized Composite Allotransplantation chronic rejection working group: 2018 American Society of Reconstructive Transplantation meeting report and white paper Research goals in defining chronic rejection in vascularized composite allotransplantation [PDF]
SAGE Open Medicine, 2020 Objectives: This report summarizes a collaborative effort between the American Society of Reconstructive Transplantation and the International Society of Vascularized Composite Allotransplantation to establish what is known about chronic rejection in ...
Christina L Kaufman +11 more
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A chronic rejection model and potential biomarkers for vascularized composite allotransplantation. [PDF]
PLoS ONE, 2020 BackgroundChronic rejection remains the Achilles heel in vascularized composite allotransplantation. Animal models to specifically study chronic rejection in vascularized composite allotransplantation do not exist so far.
Flemming Puscz +7 more
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The nature of chronic rejection after lung transplantation: a murine orthotopic lung transplant study [PDF]
Frontiers in ImmunologyIntroductionChronic rejection is a major complication post-transplantation. Within lung transplantation, chronic rejection was considered as airway centred. Chronic Lung Allograft Dysfunction (CLAD), defined to cover all late chronic complications, makes
Tobias Heigl +42 more
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Activation and Regulation of Indirect Alloresponses in Transplanted Patients With Donor Specific Antibodies and Chronic Rejection [PDF]
Transplant InternationalFollowing transplantation, human CD4+T cells can respond to alloantigen using three distinct pathways. Direct and semi-direct responses are considered potent, but brief, so contribute mostly to acute rejection.
Sumoyee Basu +11 more
doaj +2 more sources
Chronic rejection models for vascularized composite tissue allotransplantation [PDF]
Scientific ReportsVascularized composite tissue allotransplantation (VCA) has transformed patients’ lives by enabling limb, face, abdominal wall, and penile transplants.
Daniel T. Fisher +11 more
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Lymphatic Reconstruction in Kidney Allograft Aggravates Chronic Rejection by Promoting Alloantigen Presentation [PDF]
Frontiers in Immunology, 2021 Chronic rejection of the renal allograft remains a major cause of graft loss. Here, we demonstrated that the remodeling of lymphatic vessels (LVs) after their broken during transplantation contributes to the antigen presenting and lymph nodes activating.
Jinwen Lin +7 more
doaj +2 more sources
Prevention of Chronic Rejection of Marginal Kidney Graft by Using a Hydrogen Gas-Containing Preservation Solution and Adequate Immunosuppression in a Miniature Pig Model [PDF]
Frontiers in Immunology, 2021 In clinical kidney transplantation, the marginal kidney donors are known to develop chronic allograft rejection more frequently than living kidney donors.
Kotaro Nishi +6 more
doaj +2 more sources
From Transplant to Reamputation: A Case Report on Chronic Rejection and Innovative Treatment in Hand Allotransplantation [PDF]
Plastic and Reconstructive Surgery, Global OpenSummary:. Vascularized composite allotransplantation provides upper limb amputation patients with functional and aesthetic restoration but is limited by the challenges of chronic rejection.
Ahmed Elsaftawy, MD, PhD +6 more
doaj +2 more sources