Results 111 to 120 of about 2,127,841 (292)

IL-6/IL-6R Signaling Blockade Alleviates Chronic Allograft Rejection by Modulating Germinal Center B Cells and Allograft Inflammation in Murine Cardiac Transplantation

Journal of Inflammation Research
Renfei Xia,1,* Xiaoyi Shi,2,* Hengcheng Zhang,3,* Wenli Zeng,1 Zhe Yang,4 Jian Xu,1 Jianning Wang,4 Yun Miao,1 Tao Liao1,4 1Department of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People’s ...
Xia R, Shi X, Zhang H, Zeng W, Yang Z, Xu J, Wang J, Miao Y, Liao T   +8 more
doaj  

Heme oxygenase-1 modulates CD62E-dependent endothelial cell–monocyte interactions and mitigates HLA-I-induced transplant vasculopathy in mice

Frontiers in Immunology
The main risk factor for developing transplant vasculopathy (TV) after solid organ transplantation is de-novo production of donor-specific antibodies (DSAs) binding to endothelial cells (ECs) within the graft’s vasculature.
Laura Schuster, Laura Schuster, Marcin Zaradzki, Henrike Janssen, Nadia Gallenstein, Melanie Etheredge, Melanie Etheredge, Ilse Hofmann, Markus A. Weigand, Stephan Immenschuh, Jan Larmann, Jan Larmann   +11 more
doaj   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Nanoscale Secondary Ion Mass Spectrometry for Quantifying Membrane Fouling: Fouling Layer Structure and Chemical Interaction

Advanced Science, EarlyView.
Nanoscale secondary ion mass spectrometry (Nano SIMS) is established as a powerful analytical tool to visualize and quantify the membrane fouling layers. ABSTRACT Membrane technology has garnered considerable attention for applications in wastewater treatment and resource recovery. Nevertheless, membrane fouling remains a major barrier, yet the lack of
Mengfei Wu, Xinhua Wang, Pin Zhao, Weilong Song, Ming Xie   +4 more
wiley   +1 more source

Immunological factors for chronic rejection and the methods for the prevention of chronic allograft nephropathy [PDF]

, 2002
For the prevention of the immunological chronic rejection, HLA-DRB1 allele matching, enough immunosuppression in the induction phase and pathological diagnosis by non-episode and protocol biopsy are the effective methods.
高原, 史郎
core  

Chronic Allograft Dysfunction—Liver

, 2008
In the United States, more than six thousand patients undergo liver transplantation (LT) annually with generally excellent outcomes reflected in patient survival o f 88% at one year and 80% at three years and graft survival o f 83% and 74%.1 Advances in ...
Lerner, Susan, Martin, Paul, Chen, Pauline   +2 more
core   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

TGF-β, IL-6, IL-17 and CTGF direct multiple pathologies of chronic cardiac allograft rejection

, 2010
Cardiac transplantation is an effective treatment for heart failure refractive to therapy. Although immunosuppressive therapeutics have increased first year survival rates, chronic rejection remains a significant barrier to long-term graft survival ...
Adam J Booth, D Keith Bishop
core   +1 more source

Automating Chemical Reasoning in High‐Throughput Phase Identification With a Probabilistic, LLM‐Guided Framework

Advanced Science, EarlyView.
Autonomous laboratories can now synthesize materials faster than experts can interpret the resulting diffraction data. A probabilistic framework combines refinement‐fit metrics with large language model‐derived chemical reasoning to rank competing phase interpretations and flag those unsuitable for autonomous use.
Olympia Dartsi, Lauren N. Walters, Amalie E. Trewartha, Steven B. Torrisi, Amanda Volk, Liam Joyce, Gerbrand Ceder, Anubhav Jain   +7 more
wiley   +1 more source

Immunoproteasome beta subunit 10 is increased in chronic antibody-mediated rejection

, 2010
Chronic active antibody-mediated rejection is a form of late rejection with a poor prognosis. To identify specific markers of this, we analyzed several microarray studies in the literature and performed mRNA profiling of 65 biopsies and 165 blood samples
Michael Mengel, Jean-Paul Soulillou, Jovanovic, Vojislav, Mai, Hoa Le, Smit, Helga, Hoa Le Mai, Jacques Dantal, Gwinner, Wilfried, Mengel, Michael, Claire Usal, Ashton-Chess, Joanna, Vojislav Jovanovic, Ludmilla Le Berre, Guillet, Marina, Dantal, Jacques, Anne Moreau, Brouard, Sophie, Yohann Foucher, Usal, Claire, Renaudin, Karine, Foucher, Yohann, Joanna Ashton-Chess, Helga Smit, Wilfried Gwinner, Marina Guillet, Richard Danger, Moreau, Anne, Soulillou, Jean-Paul, Dugast, Emilie, Racapé, Maud, Emilie Dugast, Magali Giral, Maud Racapé, Sophie Brouard, Karine Renaudin, Giral, Magali, Danger, Richard, Le Berre, Ludmilla   +37 more
core   +1 more source